More cholesterol is associated with more vitamin D – June 2013

Vitamin D status and hypercholesterolemia in Spanish general population.

Dermatoendocrinol. 2013 Jun 1;5(3):358-62. doi: 10.4161/derm.27497. Epub 2013 Dec 18.
Cutillas-Marco E 1, Prosper AF 2, Grant WB 3, Morales-Suárez-Varela MM 4.

Low serum 25-hydroxyvitamin D [25(OH)D] levels have been associated with increased prevalence of cardiovascular diseases. A possible relation between lipids and 25(OH)D might explain this association. This investigation aimed to determine the association between vitamin D and cholesterol, as well as the influence of statins on this association. This was a cross-sectional population-based study with 177 subjects aged 18-84 years. We collected demographics and data on sun exposure, sun protection habits, current medication including lipid-lowering drugs, and estimated vitamin D intake. Serum measurements included levels of 25(OH)D, parathyroid hormone (PTH), calcium, phosphorus, total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, triglycerides, and fasting glucose. The mean 25(OH)D level was 24 ± 9 ng/ml. Young age (P = 0.04) and spending more than 1 h outdoors (P = 0.04) were independently associated with higher 25(OH)D levels. The 25(OH)D concentrations correlated negatively with total cholesterol (P = 0.01) and LDL cholesterol (P = 0.04) levels.

The adjusted OR for total cholesterol > 200 mg/ml was 2.8 (range, 1.1-7.5). Receiving statins was associated with higher 25(OH)D levels (P = 0.04). In conclusion, this study supports an association between 25(OH)D levels and cholesterol. Further studies are required to explain this association.
Download the PDF from VitaminDWiki

Cholesterol category in VitaminDWiki starts with the following

52 items below in the VitaminDWiki category = Cholesterol