Ann Transl Med . 2023 Feb 15;11(3):152. doi: 10.21037/atm-22-6515.
Hailiang Zhao1,2#, Min Wang1#, Xiaojuan Peng1,3#, Lu Zhong1#, Xiongxiu Liu1, Ying Shi1, Yuting Li1, Yanfang Chen1, Shaohui Tang1 tangshaohui206@163.com.
- 1 Department of Gastroenterology, The First Affiliated Hospital, Jinan University, Guangzhou, China;
- 2 Department of Gastroenterology, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China;
- 3 Department of Endocrinology, Liuzhou People’s Hospital, Liuzhou, China
Mortality
Cancers
Cardiovascular Disease
Cognitive
Allergic
Other
Background: Omega-3 polyunsaturated fatty acids are known to be associated with numbers of health benefits, and which can be uptake from fish. The aim of this study was to evaluate the current evidence of associations between consumption of fish and diverse health outcomes. Here, we performed an umbrella review to summarize the breadth, strength, and validity of the evidence derived from meta-analyses and systematic reviews of fish consumption on all health outcomes.
Methods: The methodological quality of the included meta-analyses and the quality of the evidence were assessed by the Assessment of Multiple Systematic Reviews (AMSTAR) and the grading of recommendations, assessment, development, and evaluation (GRADE) tools, respectively. The umbrella review identified 91 meta-analyses with 66 unique health outcomes, of which
- 32 outcomes were beneficial,
- 34 showed nonsignificant associations
- and only one was harmful (myeloid leukemia).
Results: A total of 17 beneficial associations
- [all-cause mortality, prostate cancer mortality, cardiovascular disease (CVD) mortality,
- esophageal squamous cell carcinoma (ESCC), glioma, non-Hodgkin lymphoma (NHL), oral cancer,
- acute coronary syndrome (ACS), cerebrovascular disease,
- metabolic syndrome,
- age-related macular degeneration (AMD),
- inflammatory bowel disease (IBD),
- Crohn’s disease (CD),
- triglycerides, vitamin D, high-density lipoprotein (HDL)-cholesterol, and multiple sclerosis (MS)],
and eight nonsignificant associations [colorectal cancer (CRC) mortality, esophageal adenocarcinoma (EAC), prostate cancer, renal cancer, ovarian cancer, hypertension, ulcerative colitis (UC), and rheumatoid arthritis (RA)] were evaluated as moderate/high quality of evidence. According to dose-response analyses, consumption of fish, especially fatty types, seems generally safe at one-two servings per week and could exert protective effects.
Conclusions: Fish consumption is often associated with a variety of health outcomes, both beneficial and harmless, but only about 34% of the associations were graded as based on a moderate/high quality of evidence, and additional multicenter high quality randomized controlled trials (RCTs) with a large sample size are needed to verify these findings in the future.
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Omega-3 helps with: Autism (| 9 |
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studies), Cognition (| 48 |
studies), Pregnancy (| 39 |
studies), Infant (| 31 |
studies), Obesity (| 13 |
studies), Mortality (| 5 |
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studies), Inflammation (| 18 |
studies), Multiple Sclerosis (| 9 |
studies), VIRUS (| 12 |
studies), etc
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36+ VitaminDWiki pages with FISH in the title
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Items found: 36
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Eating Fish – 17 health benefits (Omega-3 and perhaps Vitamin D) – umbrella review Feb 2023 |
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27 Feb, 2023 |
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Less muscle loss associated with eating more fish (Omega-3, Vitamin D, Magnesium, etc) – Jan 2020 |
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30 Jan, 2020 |
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Eating fish improves cognition (Omega-3 fish during pregnancy in this case) - Oct 2019 |
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06 Nov, 2019 |
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Fish in school lunches added 36 IU of vitamin D and raised blood level in winter by 2 ng – Oct 2015 |
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03 Oct, 2019 |
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Multiple Sclerosis 40 percent less likely if consume tinned fish (Vitamin D and Omega-3) – Sept 2019 |
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30 Sep, 2019 |
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The False Promise of Fish Oil Supplements (nope) Aug 2019 |
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22 Aug, 2019 |
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Pre-Multiple Sclerosis 40 percent less likely if eat canned fish – Aug 2019 |
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22 Aug, 2019 |
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ADHD children eat less fatty fish (Omega-3 again) – May 2019 |
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19 Jun, 2019 |
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Breast Cancer reduced 20 percent by fish (Omega-3) – meta-analysis Feb 2019 |
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05 Mar, 2019 |
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Farmed fish have 2X less Omega-3, 4X less Vitamin D – May 2017 |
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18 Nov, 2018 |
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Fish consumption (Omega-3) reduced death rates (421,000 people, 16 years) - July 2018 |
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21 Jul, 2018 |
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Menopause 3 years later in women eating fatty fish (Omega-3) – April 2018 |
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07 May, 2018 |
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Another Nail in the Coffin for Fish Oil Supplements (nope) – JAMA April 2018 |
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18 Apr, 2018 |
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Fish oil increased Vitamin D levels, krill oil decreased them – RCT Jan 2018 |
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27 Jan, 2018 |
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Vitamin D levels in Alaska are decreasing – does less fish mean less health – Aug 2017 |
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05 Sep, 2017 |
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Importance of Vitamin D and fish rarely mentioned during midwife-led prenatal booking visits – July 2017 |
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07 Aug, 2017 |
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Fish (Omega-3, Vitamin D) as Medicine for Rheumatoid Arthritis – June 2017 |
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21 Jun, 2017 |
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High level of Mercury in umbilical cord was 2.9 times more likely if eat fish instead of vitamin D supplements – March 2017 |
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04 Mar, 2017 |
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Fatty Fish in diet increases vitamin D level a few nanograms – meta-analysis Sept 2015 |
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10 Dec, 2016 |
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Alaskan natives now eat far less fish and have far lower levels of vitamin D – July 2016 |
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29 Jul, 2016 |
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Hypothesis - oil spill reduces sunlight to plankton which reduces Vitamin D to fish - June 2016 |
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05 Jul, 2016 |
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Multiple Sclerosis risk reduced 46 percent by Omega-3 derived from fish (1 gram) – Sept 2015 |
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13 Mar, 2016 |
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Popular supplements 1 Vitamin D, 2 fish oil, 3 CoQ10, 4 multivitamins 5 probiotics - Feb 2016 |
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27 Feb, 2016 |
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Vitamin A and dioxin-like compounds in fish liver, etc may block vitamin D – July 2012 |
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31 May, 2015 |
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Japanese men eating small fish were 32 percent less likely to get diabetes – Aug 2011 |
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06 Mar, 2015 |
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Supplements survey: Fish oil 1st, Vitamin D 4th, Magnesium 6th, Calcium 7th - March 2015 |
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01 Mar, 2015 |
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Farmed fish not have enough vitamin D to increase levels – RCT Feb 2014 |
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27 Jan, 2015 |
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Greenlanders – higher vitamin D if eat more Inuit foods (fatty fish, etc) – Aug 2013 |
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15 Aug, 2014 |
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Elderly 3X more likely to have 30 ng of vitamin D if frequently eat fatty fish, eggs – Aug 2013 |
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15 Aug, 2014 |
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More vegetables or fish, less Cancer – June 2014 |
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15 Jul, 2014 |
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Health professionals: about 10X more were using Vitamin D, fish oil, folic acid by 2006 – March 2014 |
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13 Jun, 2014 |
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Off topic: Healthcare Needs Insurance Companies Like a Fish Needs a Bicycle |
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09 Nov, 2012 |
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A fish a day keeps the doctor away – Japan 2002 |
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04 May, 2011 |
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Fish need vitamin D and C for their bones – Dec 2010 |
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09 Jan, 2011 |
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Fish oil and vitamin D reduced breast cancer in rats – June 2010 |
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07 Jul, 2010 |
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Some fish can see in UV – Feb 2010 |
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05 Jul, 2010 |