Stroke
Stroke Category highlights - includes post-stroke
items in stroke category - see also Overview Stroke and vitamin D,
Overview Hypertension and Vitamin D Overview Cardiovascular and vitamin D
Stroke more likely if low Vitamin D
Stroke 74% less likely if high vitamin D (7,295 women 20-50 years old) – July 2017
Stroke is 13.5 X more likely if low vitamin D and high blood pressure – March 2015
Ischemic stroke 17 X more likely if low vitamin D – April 2017
Ischemic Stroke 3X more likely if Vitamin D Receptor gene change (Fok 1) – Jan 2014
Post-Stroke worse if low Vitamin D
Poor Acute Ischemic Stroke 4X more likely if low Vitamin D - Nov 2023
Stroke risks increased if low Vitamin D: Death 3.6 X, recurrence 5.5 X – Meta-analysis Nov 2019
Stroke outcome at 3 months was 3X worse if bad stroke and low vitamin D – Jan 2020
Death after Ischemic Stroke 2.5 X more likely if less than 10 ng of Vitamin D – May 2019
Vascular dementia (after strokes) 32X more likely in Hypertensives with low vitamin D – Oct 2015
Depression following a stroke is 2.7 X more likely if low vitamin D – Sept 2018
Stroke incidence not associated with low Vitamin D (but stroke outcome is) – Aug 2019
Post-Stroke better if add Vitamin D
Post-stroke Vitamin D supplementation helped in 11 ways – May 2023
Improved recovery from ischemic stroke with Vitamin D (300,000 IU injection) – RCT June 2018
Better outcome following Ischemic stroke if injected with 600,000 IU of vitamin D – RCT Feb 2017
Stroke patients need more than 2,000 IU of vitamin D (found this time in Japan) – RCT June 2019
Post-Stroke better if Vitamin D actually gets to cells
Resveratrol fights Parkinson, Alzheimers, Diabetes, Cardiovascular, ALS, Stroke, etc.– Nov 2018
Stroke rehabilitation (and prevention) requires Vitamin D actually getting to cells – March 2020
studies in both categories of Depression and Stroke
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Post-Stroke depression is 3.5X more-likely if vitamin D deficient - meta-analysis - Aug 2024
Vitamin D Deficiency in the Acute Phase of Stroke May Predict Post-stroke Depression: A Systematic Review and Meta-Analysis
Journal of Geriatric Psychiatry and Neurology https://doi.org/10.1177/08919887241275044
It says PDF is behind a paywall, but also says that it is available via creative common liscnse
Yongjun Tan, PhD, Xiaojun Jing, MD, […], and Qin Yang, PhD https://orcid.org/0000-0003-4040-1661 zhanghuapro@hospital.cqmu.edu.cn+4
To conduct the association between vitamin D levels in the acute phase of stroke and post-stroke depression (PSD) in stroke patients.
Methods
Five international databases (PubMed, Web of Science, Embase, Ovid MEDLINE(R), Cochrane Library) and one Chinese database (Wanfang Data) were searched for observational studies in any language reporting on PSD and vitamin D levels tested in the acute phase of stroke in stroke patients from inception to May 2024. Data extraction and study quality assessment were conducted by two authors independently. Qualitative and quantitative analyses of data were performed. The meta-analysis was registered in the PROSPERO database (CRD42023398581).
Results
We included 7 studies containing 3537 participants in the systematic review and meta-analysis. All studies that met the inclusion and exclusion criteria were conducted in China. Vitamin D levels in the acute phase of stroke were lower in PSD patients compared with non-PSD patients (weighted mean difference = −14.97 nmol/L; 95% confidence interval = −19.54, −10.40).
Stroke patients with vitamin D deficiency (<50 nmol/L) had an increased risk of PSD compared with stroke patients with vitamin D sufficiency (≥75 nmol/L) ( odds ratio = 3.59 ; 95% confidence interval = 2.05, 6.27). However, the association between vitamin D insufficiency (50-75 nmol/L) and PSD were not statistically significant (odds ratio = 4.15; 95% confidence interval = 0.87, 19.78).
Conclusion
Vitamin D deficiency in the acute phase of stroke may be a risk factor for PSD.
20 Most-visited pages in the Stroke category in VitaminDWiki
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All Stroke items
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VitaminDWiki - studies in both categories Depression and Stroke
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Stroke is associated with categories: Cardiovascular 14, Cognitive 13, Hypertension 10, Depression 9, Intervention 7, Mortality 6, Diabetes 5, Skin - Dark 5, Virus 5, Injection 4, Vitamin D Receptor 4,
Detailed Associations with the Stroke Category
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