Lower vitamin D in blood causes Alzheimer's Disease (Mendelian gene analysis) – Dec 2019

• Many other studies have found Vitamin D to be associated with Alzheimer's Disease
• This study found that genes which result in lower blood level of vitamin D are associated with Alzheimer's Disease

This study appears to ignore the 7 additional genes which can further decrease the amount of Vitamin D actually getting to the brain

• Alzheimer’s is associated with all 7 of the genes which restrict vitamin D from getting to tissues – Sept 2018
• 8 genes associated with both Alzheimer’s and lowish Vitamin D – May 2019
• Resveratrol improves health (Vitamin D receptor, etc.) - many studies
  • Resveratrol INCREASES the Vitamin D getting from the blood to the cells
• 16 articles are in both Cognition and Vitamin D Receptor categories
• 9 articles are in both Cognition and Vitamin D Genes categories

• Alzheimer’s Disease risk is 1.3X higher if Vitamin D deficient – meta-analysis Nov 2019
• Risk of Dementia and Alzheimer's reduced by higher levels of Vitamin D – meta-analysis Feb 2018
  Risk of Alzheimer's decreases as Vitamin D increases

Overview Alzheimer's-Cognition and Vitamin D starts with

• FACT: Cognitive decline is 19X more likely if low vitamin D
• FACT: Dementia is associated with low vitamin D levels.
• FACT: Alzheimer’s Dementia 2.3X more likely in elderly if low vitamin D – Dec 2022
• FACT: Dementia is associated with low vitamin D - many studies
• FACT: Alzheimer's Disease is 4X less likely if high vitamin D
• FACT: Every single risk factor listed for Alzheimer's Disease is also a risk factor for low vitamin D levels
• FACT: Elderly cognition gets worse as the elderly vitamin D levels get even lower (while in senior homes)
• OBSERVATION: Reports of increased vitamin D levels result in improved cognition
• OBSERVATION: Alzheimer’s patients 3X more likely to have a malfunctioning vitamin D receptor gene – 2012
• OBSERVATION: Alzheimer's Disease has been seen to halt when vitamin D was added.
• OBSERVATION: Alzheimer’s is associated with all 7 of the genes which restrict vitamin D
• OBSERVATION: 39 vitamin D and Alz. or Cognition intervention trials as of Sept 2018
• OBSERVATION: 2 Meta-analysis in 2012 agreed that Alzheimer's Disease. associated with low vitamin D
• OBSERVATION: 50X increase in Alzheimer's while decrease in vitamin D
• OBSERVATION: Vitamin D reduces Alzheimer’s disease in 11 ways
• OBSERVATION: Alzheimer’s cognition improved by 4,000 IU of vitamin D
• OBSERVATION: Plaque removed in mice by equiv. of 14,000 IU daily
• OBSERVATION: DDT (which decreases Vit D) increases risk of Alzheimer's by up to 3.8X
• OBSERVATION: 2% of people have 2 copies of the poor gene reference: Alz Org
• OBSERVATION: Genes do not change rapidly enough to account for the huge increase in incidence
• OBSERVATION: End of Alzheimer's videos, transcripts and many studies protocol has been very successful
  • It adjusts Vitamin D, B-12, Iron, Omega-3, food, etc, and can now be done at home.
• FACT: Vitamin D is extremely low cost and has very very few side effects
• CONCLUSION: Everyone concerned about cognitive decline or Alzheimer's Disease should take vitamin D
• PREDICTION MET: By 2024 Omega-3 and high dose Vitamin D will be found to reverse Alzheimer's in humans
  There are 13+ Alzheimer’s meta-analyses in VitaminDWiki
  There are 97+ Alzheimer’s studies in VitaminDWiki
  Dementia is associated with low vitamin D - many studies 50+ studies
  16+ studies in both categories Cognitive and Omega-3