Vitamin D shows in vivo efficacy in a placebo-controlled, double-blinded, randomised clinical trial on canine atopic dermatitis
VetRecord – BMJ, http://dx.doi.org/10.1136/vr.104492
Christoph J Klinger1 klingerchristoph@icloud.com, Stefan Hobi1, Cornelia Johansen1, Hans-Joachim Koch2, Karin Weber1 and Ralf S Mueller1
1 – Clinic of Small Animal Medicine, Ludwig Maximilian University, Munich, Germany
2 – Tierärztliche Klinik Birkenfeld, Birkenfeld, Germany
Veterinary was the very first category made in VitaminDWiki 8 years ago
Farm animal doctors are paid to keep their patients healthy, vs human doctors are paid to treat sick patients
Doctors for farm animals appeared to be about 10 years ahead of doctors for humans
Vets routinely prescribe 3X more Vitamin D than the govt recommends – because it keeps their animals healthy
Items in both categories Skin and Inflamation are listed here:
- Atopic Dermatitis not helped by small weekly doses of Vitamin D (8K 2y-6y.16K 12y-18y) – RCT March 2024
- Eczema (Atopic Dermatitis) treated by 1,600 IU Vitamin D (again) – Meta-analysis Aug 2019
- Increased risk of atopic dermatitis with low vitamin D during pregnancy perhaps due to poor methylation – Oct 2018
- Atopic dermatitis treated by Vitamin D (in dogs too) - RCT Feb 2018
- Eczema (Atopic Dermatitis) treated by 1600 IU of vitamin D – meta-analysis Dec 2016
- Atopic Eczema might be helped by Vitamin D – Review May 2015
- Dermatologists still not convienced that Vitamin D reduces atopic dermatitis – Review Dec 2013
- Eczema 25 percent more likely if low vitamin D– July 2013
- Atopic dermatitis dramatically reduced in Iran with 1600 IU of vitamin D – RCT March 2012
- Atopic Dermatitis and Eczema - many studies
- Atopic dermatitis worse for those with low vitamin D – Nov 2010
Veterinary
- Veterinary and Vitamin D category listing has
151 items along with related searches - Companion animals (dog, cats) need vitamin D too – March 2016
- Rickets increasing in dogs
- Dogs with Cancer have low vitamin D, same as humans – Sept 2017
- Dogs, like humans, need vitamin D for many reasons – Jan 2018
- Hospitalized cats 8X more likely to die if low vitamin D (Vit. D helps humans too) – May 2015
Atopic dermatitis (AD) in dogs is among the most common skin diseases in small animal practice. It is an inflammatory disease based on a genetic predisposition to develop hypersensitivity against environmental and food allergens and typical clinical signs up exposure. Treatment sometimes can be difficult and associated with adverse effects. Previous studies evaluating cholecalciferol as treatment for human AD have shown promising results. With canine AD being a good animal model for its human counterpart, it was hypothesised that cholecalciferol might have beneficial clinical effects in dogs, too. In this randomised, placebo-controlled, double-blinded eight-week cross-over study, 23 client-owned dogs received either systemic cholecalciferol (n=16), a vitamin D receptor analogue (n=8) or placebo (n=13). Blood samples for ionised calcium were obtained regularly during the study, and Canine Atopic Dermatitis Extent and Severity Index and pruritus scores, blood levels of vitamin D metabolites, measurements of skin pH and transepidermal water loss were determined before and after.
Pruritus and lesion scores decreased significantly in the cholecalciferol group versus placebo. No differences in water loss or skin pH were observed. An increase in serum 25-hydroxycholecalciferol strongly correlated with a reduction in pruritus. Systemic cholecalciferol may be a viable treatment option for canine AD.Printer Friendly Follow this page for updates5003 visitors, last modified 09 Aug, 2019,