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Increased risk of atopic dermatitis with low vitamin D during pregnancy perhaps due to poor methylation – Oct 2018

Prenatal 25-hydroxyvitamin D deficiency affects development of atopic dermatitis via DNA methylation.

J Allergy Clin Immunol. 2018 Oct 20. pii: S0091-6749(18)31477-5. doi: 10.1016/j.jaci.2018.10.010.
Cho HJ1, Sheen YH2, Kang MJ3, Lee SH3, Lee SY4, Yoon J5, Jung S4, Lee SH3, Kim YH4, Yang SI6, Lee E7, Seo JH8, Ahn K9, Kim KW10, Suh DI11, Won HS12, Lee MY12, Kim SH13, Choi SJ14, Kwon JY15, Jun JK16, Kwon SO17, Oh SY18, Hong SJ19.

Due to the hypomethylation and consequently increased expression of oxidative stress-promoting genes in severely vitamin D-deficient fetus, the resulting offspring is predisposed to subsequent AD development and its severity.

Publisher wants $39 for the PDF, no response by Sci-hub on Oct 24, 2018

See also VitaminDWiki

Atopic Dermatitis Overview in VitaminDWiki

Inflamation AND Skin

Methylation and Epigenetics

Created by admin. Last Modification: Wednesday October 24, 2018 16:57:10 GMT-0000 by admin. (Version 5)