Association between Vitamin D and Dental Caries in a Sample of Canadian and American Preschool-Aged Children
by Tiffany L. Williams 1,Joseph Boyle 2,Betty-Anne Mittermuller 3,4,Caroline Carrico 1 andRobert J. Schroth 3,4,5,6,7,*ORCID
Nutrients 2021, 13(12), 4465; https://doi.org/10.3390/nu13124465
Background: Inadequate vitamin D levels may increase the risk of caries during childhood. The purpose of this study was to investigate the association between 25-hydroxyvitamin D (25(OH)D) status and severe early childhood caries (S-ECC) in preschool children.
Methods: Data were obtained from children <72 months of age in two case–control studies in Winnipeg, Manitoba and Richmond, Virginia. Serum analysis assessed 25(OH)D, calcium and parathyroid concentrations. Data on demographics, dental history and oral hygiene were obtained via questionnaires. Bivariate and multiple logistic regression analyses were performed to assess the relationships between demographic and biological variables and S-ECC. A p-value of ≤0.05 was significant.
Results: Data were available for 200 children with S-ECC and 144 caries-free controls. Children with S-ECC had significantly lower 25(OH)D levels than those who were caries-free (p < 0.001), and children with deficient 25(OH)D levels were 10 times more likely to have S-ECC (p < 0.001). Multiple logistic regression revealed that having higher 25(OH)D and calcium concentrations (p = 0.019 and p < 0.0001, respectively), as well as being breastfed in infancy (p < 0.001), were significantly and independently associated with lower odds of S-ECC, while dental insurance (p = 0.006) was associated with higher odds of S-ECC.
Conclusions: This study provides additional evidence of an association between nutritional status, specifically vitamin D and calcium levels, and S-ECC.
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Caries 3.5X more likely at age 8 if <20n/ml of vitamin D (Spain) - Sept 2021
VitaminDWiki - Dental category
Some Dental studies
- Vitamin D cut dental caries in half 80 years ago – meta-analysis 2013 80 years ago
- Caries (tooth decay) and Vitamin D - 23+ studies
- Periodontitis reduced by Vitamin D - many studies
- Risk of Oral Surgery reduced by Vitamin D – scoping review Nov 2021
- Some Dental Malocclusions 5X more likely if low vitamin D – June 2021
- Grinding teeth while sleeping (sleep bruxism) 6 X more likely if low vitamin D – Jan 2021
- Early tooth decay 1.9 X more likely if a poor Vitamin D receptor – July 2017
7 Intervention AND Dental studies 19 items listed in BOTH Dental and Infant or Child 7 listed in BOTH Dental and Vitamin D Receptor
Pages listed in BOTH Dental and Infant or Child
- Childhood Dental Caries about 2X more likely if Vitamin D is less than 20 ng – review April 2024
- Early Childhood Caries 1.4 times more likely if 20-30 ng of Vitamin D – meta-analysis Jan 2024
- Caries in deciduous teeth about 2X more likely if low vitamin D – Review Nov 2023
- Severe infant caries 10X higher risk if low vitamin D (under 14 ng) - Dec 2021
- Virtually all infants in Poland got 400 IU of Vitamin D daily (not enough, non-daily is better) – April 2021
- More dental caries in children who have less than 30 ng of Vitamin D – Review Sept 2020
- Teeth from 19th century London indicate that most children were Vitamin D Deficient - Oct 2019
- Half as many tooth enamel defects in child if 2400 IU Vitamin D in late pregnancy – RCT Aug 2019
- Half as many teeth problems if higher cord blood level of vitamin D – March 2019
- No tooth decay in children with adequate Vitamin D (small study) – June 2018
- Early tooth decay 1.9 X more likely if a poor Vitamin D receptor – July 2017
- Severe childhood dental problems 2.4 X more likely if breastfed for more than two years (low vitamin D) – June 2017
- Dental Caries risk in children cut in half if more than 20 nanogram of Vitamin D – Nov 2015
- Teeth enamel problems (MIH) 11 percent less likely with just 4 ng more vitamin D – Dec 2014
- 3X fewer infant dental caries if good level of vitamin D while pregnant – April 2014
- Severe tooth decay in children unless supplemented with Vitamin D drops – Oct 2013
- UVB added in classroom reduced cavities, increased height, increased academics. etc
- Dental caries cut in half by vitamin D, review of 24 old clinical trials – Nov 2012
- Children with severe caries were 2X more likely to have inadequate vitamin D – July 2012
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