- Assessment of the Relation Between Asthma Severity and Serum Vitamin D Levels: A Cross-Sectional Study
- Similar previous studies in VitaminDWiki
- It appears that severe asthmatics have poor guts, which results in less vitamin D getting into the body
- See also VitaminDWiki
- Overview Asthma and Vitamin D contains
Assessment of the Relation Between Asthma Severity and Serum Vitamin D Levels: A Cross-Sectional Study
Cureus 15(10): e46826. DOI: 10.7759/cureus.46826
Navjot Kaur • Vipul Kumar • Jagjot Singh • Hritvik Jain • Paras Paras • Nirmaljeet Kaur • Ashwani K. Sareen
The more severe the Asthma, the lower the vitamin D level
Introduction
Vitamin D3’s importance for bone health in children and its potential role beyond musculocutaneous health is an ongoing area of research. This study assesses vitamin D3 deficiency prevalence in asthmatic children and its correlation with asthma cases and healthy controls.
Methods
This cross-sectional study was conducted in a tertiary care hospital in Punjab, India among children between 5 and 15 years of age. Fifty children diagnosed with “bronchial asthma” who were under follow-up in the asthma clinic in outpatient and inpatient patients were enrolled as cases. Age-matched 50 healthy controls who presented for routine check-ups were enrolled in the control group. Demographic details were noted and clinical examination was done in all the cases. 25-(OH) vitamin D levels were estimated and compared in all cases and controls. The study also analyzed the relationship between 25-(OH) vitamin D levels with asthma control and severity.
Results
The study showed that serum vitamin D3 level was significantly decreased in asthmatic children (24.62 ± 14.95 ng/ml) as compared with the healthy control group (32.08 ± 12.22 ng/ml). Also, serum vitamin D3 level was significantly decreased in children with uncontrolled asthma (12.06 ± 4.68 ng/ml) as compared to children with well-controlled asthma (44.82 ± 10.48 ng/ml).
Conclusion
The findings showed that low serum levels were observed more in asthmatic children as compared to healthy children. A correlation was also found between vitamin D3 levels and asthma severity, its control, and the number of acute exacerbations in the last year.
Download the PDF from VitaminDWiki
Similar previous studies in VitaminDWiki
The worse the bronchial asthma, the lower the vitamin D – Jan 2017
Vitamin D levels vs bronchial asthma
The worse the asthma in children, the lower their vitamin D level - Feb 2019
It appears that severe asthmatics have poor guts, which results in less vitamin D getting into the body
Wheezing and asthmatic children have weaker Vitamin D responses - May 2022
Asthma and the risk of gastrointestinal disorders: a Mendelian randomization study - March 2022
https://doi.org/10.1186/s12916-022-02283-7 FREE PDF
"It was found that people with asthma are three times more likely to have gastroesophageal reflux than healthy people [11]. Additionally, it could be shown that the risk of asthma in subjects with IBS is twice the risk in persons without the disease "
Solution: Use a gut-friendly form of Vitamin D
See also VitaminDWiki
Severe asthmatics willing to pay 5180 dollars for relief, Vitamin D needed costs only 45 dollars – Sept 2023
Poor response to Asthma inhaler if poor Vitamin D Receptor – Dec 2019
Overview Asthma and Vitamin D contains
- VitaminDWiki pages containing ASTHMA in title (164 as of Nov 2024)
- Asthma attacks reduced in half if Vitamin D level higher than 42 nanograms – RCT May 2014
- Started with 100,000 IU loading dose and has standard-of-care Asthma drug
- Asthma may be treated by Vitamin D if more than 40 ng for 12 months – Sept 2018
- Those with Asthma or COPD had half the response to Vitamin D – March 2020
- Those with Asthma need larger doses to get the same response.
- Probably need gut-friendly Vitamin D
- CDC funded study: 1.3 X Asthma risk if vaccination contained aluminum – Sept 2022
- Asthma occurrence rate reduced 3X by Vitamin D – 8 study meta-analysis - Aug 2021
- Asthma in child 2.3 X more likely if both parents asthmatic (unless add Vitamin D) – VDAART Nov 2018
- Adult-onset asthma 2X more likely if low vitamin D and not hyperallergenic – May 2018
- Children had poor lung function if mothers had low vitamin D while pregnant – Nov 2022
- 26 health factors increase the risk of COVID-19 – all are proxies for low vitamin D
- CDC list of high-risk for COVID-19 includes Asthma
- Child Asthma increased 2.1 X by antibiotics, Child milk allergy increased 4.4 X by PPI – April 2018
- Asthmatic children taking Corticosteroids had 2X more vitamin D intake, but lower levels – July 2017
- Traffic pollution increases asthma unless supplement with Vitamin D (mice) June 2018
- Childhood asthma problems eliminated for months by 600,000 IU of Vitamin D injection – June 2017
- Proof that Vitamin D Works 92 health problems prevented/treated as of Nov 2020
- Asthma has been proven to be treated by Vitamin D in at least 4 random controlled trials
- Childhood asthma still reduced 4 months after 800 IU of Vitamin D daily - RCT Feb 2016
- Respiratory Disease exacerbations (Asthma, CF, COPD) may be treated by Vitamin D – July 2019
- Women with asthma 35X more likely to be vitamin D deficient – Oct 2013
- If high vitamin D during pregnancy the child is 5X less likely to get asthma
- Asthma is treated by Vitamin D – now they are trying to understand why – Feb 2015
- Increase in vitamin D deficiency may partially explain increases in asthma and allergies – Jan 2015
- Why deficiencies in vitamin D and magnesium are linked to asthma Magnesium allows muscles to relax
- Babies 3.6X more likely to go to hospital for asthma if asthmatic mother had low vitamin D while pregnant – June 2019
- The worse the bronchial asthma, the lower the vitamin D – Jan 2017 has the following chart
click on the chart to see the study