Pages tagged with "Kidney"

252 pages, most important first (overviews, then meta-analyses, then RCTs, then newest). Combine with another topic

• Overview Kidney Stones and vitamin D
• Overview Kidney and vitamin D
• Vitamin D testing typically not needed, but in 9 cases it is
• Vitamin D helps organ transplant - many studies
• 90 percent of U.S. adults have CKM syndrome - defined in 2023
• Chronic Kidney Disease needs Vitamin D - many studies
• Kidney Dialysis, low Vitamin D, low Magnesium - many studies
• Hemodialysis and Vitamin D - many studies
• Omega 3 increases vitamin D in the blood – many studies
• Peptides enhance Vitamin D's effects — what several studies have found
• Patients on Hemodialysis 3X more likely if die of heart failure if low Magnesium – meta-analysis
• Dialysis patients 23 percent more likely to live if had just 10 ng more Vitamin D – meta-analysis
• Chronic Kidney not helped much by little vitamin D (none got to a 75 nmol level) – meta-analysis
• Dialysis patients who added Vitamin D were 41 percent less likely to get infection – Meta-analysis
• Kidney stone risk varies a lot with both genetics and race – meta-analysis
• Vitamin D supplementation and fewer kidney stones – meta-analysis of RCT
• Kidney failure 1.1 X more likely if poor Vitamin D Receptor – meta-analysis
• Diabetic nephropathy (Kidney problem) 1.8 X more likely if poor Vitamin D Receptor – meta-analysis
• Vitamin D helps Diabetic Nephropathy kidneys – meta-analysis
• Chronic Kidney Disease mortality is 60 percent less likely if good vitamin D – meta-analysis
• Chronic Kidney disease not helped much by vitamin D provided you ignore dose size – meta-analysis
• Kidney cancer 22 percent less likely if high vitamin D – meta-analysis
• Kidney stones associated with higher vitamin D (but not agree how much 20-100 ng) – meta-analysis
• Vitamin D reduced risk of death of Chronic Kidney Disease by 30 percent: Meta-analysis
• Standard and artificial vitamin D both help Chronic Kidney Disease – meta-analysis
• Each 10 ng increase in vitamin D decreased kidney disease death by 14 percent
• Chronic Kidney Disease meta-analysis of vitamin D
• Meta-analysis finds vitamin D helps chronic kidney disease
• Fracture 4X less likely following kidney transplant if high-dose Vitamin D (100,000 every 2 weeks) – RCT
• Vitamin D treatment of Chronic Kidney Disease: monthly better than daily – RCT
• Hyperparathyroidism resulting from CKD eliminated by 8,000 IU of vitamin D daily for 12 weeks– RCT 2018
• Diabetic nephropathy (Kidney) treated by 50,000 IU of vitamin D weekly – RCT
• Urate (kidney stones, gout) reduced by Calcium – RCT
• Hemodialysis not helped by weekly vitamin D2 – RCT
• 4X reduction in bone fractures following Kidney Transplant with monthly Vitamin D (100,000 IU) - RCT
• Chronic Kidney Disease reduced with 3600 IU vitamin D (50000 twice a month)– RCT
• Osteoporosis interactions with gut, brain, liver and kidney (not just joints)
• 5X less risk of Kidney cancer if good ratio of Vitamin D binding protein to circulating vitamin D
• Hypothesis: Vitamin D Binding Protein limits vitamin D benefits outside of kidney too
• Kidney failure 1.7X more likely - Vitamin D Binding Protein
• Kidney Cancer 4X more likely if poor Vitamin D Binding Protein (5X in previous study)
• 35 tissues activate Vitamin D locally (Kidney not required)
• Last in health, last in funding: Native American's double burden
• Time-release form of active vitamin D granted a patent for chronic kidney disease
• Peritoneal Dialysis removes protein, Vitamin D, magnesium, etc.
• Vitamin D decreases incidence of disease
• Glutathione fights: Diabetes, Alz, PD, NAFLD, Kidney, UC, IBD, HIV, Fatigue, etc,
• Childhood Dialysis - 64% death rate if very low vitamin D
• Vitamin d levels were restored from hemodialysis by 70,000 IU weekly total in 4 weeks
• Heart problems 5X worse for chronic kidney patients low on vitamin D
• Difficult to estimate Vitamin D in a cell (Kidney in this case)
• Metformin appears to activate the Vitamin D Receptor (more D to kidney cells, etc,)
• Glutathione fights Alz, Park, Cardio, Liver, COPD. Asthma, etc
• Top 10 health problems worse since COVID-19
• Magnesium Depletion Score predicts increased risk of various health problems
• Chronic Kidney Disease increases risk of Parkinson's Disease by 4X (both fought by Vitamin D)
• Kidney dysfunction associated with low vitamin D
• Kidney may not be required to activate Vitamin D
• Death after surgery for chronic kidney disease 2.3 X more likely if low Vitamin D
• New case of diabetes 2X more likely after kidney transplant if low Vitamin D
• Vitamin D, minerals (Mg, Ca, K, Phosphate, Na, Fe, Zn, Cl, Se) and health – 15 studies 2024
• Kidney disease with sepsis: mortality reduced 40% by Vitamin D (dose not specified)
• How vitamin D benefits normal organs and Long-COVID organs
• People with Sepsis and Kidney injury and who got vitamin D were much more likely to survive
• Vitamin D is the 3rd best predictor of bleeding after hemodialysis
• Obese person with a cancer is 1.7 X higher risk of subsequent Kidney Cancer (low vitamin D)
• Vitamin D would probably help both CKD and Kidney transplant (PDF behind paywall)
• Vitamin D can be activated in many tissues - no Kidney needed
• DNA analysis of genes (Polygenic risk) shows increased risk of 9 health problems (all 9 fought by Vitamin D)
• Bone biomarkers increased equally by daily, weekly, or monthly Vitamin D (CKD in children in this case)
• Hemodialysis with low vitamin D increases risk of 2 health problems by 10 percent
• Kidney Dialysis often filters out Vitamin D, a problem for vegetarians and others
• Vitamin D is needed during Dialysis – initially only 29 pcnt tested, extensive education raised it to 32 pcnt
• 2.8X more likely to die of hemodialysis if low on vitamin D
• Peritoneal dialysis probably consumes a lot more vitamin D than haemodialysis
• Poor cognition 2X more likely in Hemodialysis Patients if low Vitamin D
• The potential role of vitamin D binding protein in kidney disease: a comprehensive review
• Kidney
• 26 health factors increase the risk of COVID-19 – all are proxies for low vitamin D
• Kidney Dialysis clinics reluctant to add vitamin D treatment as they are not reimbursed
• 1 in 10 have Chronic Kidney Disease (but only 5% are aware of it) – review
• Fructose reduces blood levels of active vitamin D
• Chronic Kidney disease 15 X more likely if Vitamin D deficient (Chinese males)
• Vitamin D3 becomes Calcidiol which becomes Calcitriol
• Vitamin D activation is mainly done by the tissues, not the Liver and Kidneys
• Brain cells can probably activate Vitamin D without liver or kidney (at least in rats)
• Kidney patients who happened to be getting high-dose Calcitriol were 9X less likely to die of COVID-19
• Need at least 80 ng of vitamin D if have chronic kidney disease
• More than 30 ng of vitamin D is sometimes needed (Kidney needs 50 ng)
• Vitamin K2 MK- 7 not as available if have Chronic Kidney Disease
• 4X more Chronic Kidney disease patients are now using vitamin D
• Calcitriol (active Vitamin D) prevents and treats COVID (with Chronic Kidney Disease in this case)
• All children with Chronic Kidney Disease had low Vitamin D (Pakistan hospital)
• Hemodialysis patients (CKD) helped by weekly 50,000 IU of vitamin D
• Hemodialysis deaths less likely if take vitamin D, especially if highest dose vitamin D
• Kidney disease helped by active or high dose Vitamin D
• Lowering Calcium Risk when having High Dose Vitamin D3 – Cawley
• Kidney Inflammation not reduced by 30 ng Vitamin D (many health problems need 50 ng)
• Inflammatory diseases: review of vitamin D, with many tables
• Kidney Inflammation: both prevented and reduced by Vitamin D – review
• Inflammation and Vitamin D in Chronic Kidney Disease
• Hypothesis: Magnesium might prevent and treat Chronic Kidney Disease
• Diabetics 5X more-likely to get CKD if have very low Vitamin D
• Poor kidneys rarely get enough or the right form of vitamin D
• Chronic Kidney Disease study not aware of appropriate forms of vitamin D
• Low magnesium if poor kidney, poor gut, cancer, cancer drugs
• Inflammation of blood vessels (vasculitis): low Vitamin D and 22 X more likely to have kidney problems
• Fully-activated Vitamin D (Calcitriol) is produced inside and outside of the kidneys
• Kidney not essential for Vitamin D3 activation – fungi can do it
• 1,000 IU of vitamin D provides little benefit (Kidney transplant in this case)
• Modified release active Vitamin D (calcifediol ) for those with poor Kidney function (USD 10,000 per year)
• More people with Chronic Kidney Disease are now getting Vitamin D prescriptions (India)
• Gave vitamin D, decided that heavier needed more (kidney disease in this case)
• Kidney transplant rejection 1.8X more likely if low vitamin D
• Kidney transplant worked better if initially have high level of vitamin D
• Chance of Acute Kidney Injury during next 20 years increased 35 percent if single low Vitamin D measurement
• Kidney Stones are related to poor genes – example of CYP24A1 (Vitamin D)
• Kidney stones Vitamin D myth from medical book - 2010
• For COVID-19: Vitamin C use might cause kidney stones, but Vitamin D will not
• Hemodialysis associated with very poor mRNA response (wonder if low vitamin D)
• Dialysis patients with low vitamin D were 2.7 X more likely to die of heart problems
• Kidney transplant patients advised to avoid the sun, then 90% have very low vitamin D levels
• Calcitriol (active Vitamin D) recommended after kidney transplant
• Even with vitamin D supplementation Kidney transplant patients were deficient
• Various forms of Vitamin D help with Glomerulonephritis (a kidney disease)
• Vitamin D testers have different test results if there is chronic kidney disease
• Peritoneal Dialysis nicely treated by active vitamin D
• Standard oral vitamin D is not a good way to supplement if have Chronic Kidney Disease
• Chronic Kidney Disease Patients need Vitamin K
• Kidney diseases and COVID-19 – probably helped by Vitamin D etc.
• Adding Vitamin D decreased kidney deaths by 4x
• Chronic Kidney Disease decreases Vitamin D in 4 ways
• Vitamin D deficiency associated with increased risk of many health problems in 58,000,000 Americans
• Kidney Stones
• Those Dialysis patients with low vitamin D were 75% more likely to die
• Majority of blacks on dialysis were vitamin D deficient
• Blacks have 4X more Kidney disease than whites – probably due to low vitamin D
• Sudden kidney infection in children was 9X more likely if poor Vitamin D receptor
• Chronic Kidney Disease (stage 3) slowed by 30 ng of Vitamin D and Calcitriol
• HFCS or fructose decreases Calcium and vitamin D if have CKD
• Chronic Kidney Disease patients need more than 20 ng of Vitamin D – workshop conclusion
• UVB increases vitamin D even if poor kidney by changing CYP27B1 genes in skin
• CYP27B1 gene decreases kidney production of active vitamin D
• 2.4 times more likely to die if have Chronic Kidney Disease and low vitamin D
• Diabetic kidney problems in children last longer if low vitamin D
• Half as much chronic kidney disease infection if supplement with Vitamin D – 2018
• Mutations in CYP24A1 gene (vitamin D) associated with kidney problems
• Better Cancer survival if higher vitamin D a decade earlier (esp. Melanoma, Kidney, Prostate)
• Chronic kidney treatment by Vitamin D lacks consensus: type, how much
• Diabetic Nephropathy – active vitamin D helps
• Kidney problems reduces Vitamin K. which causes cardiovascular problems
• Dialysis patients with higher levels of vitamin D were better
• Kidney Stones risk increased 1.3 X to 2 X by antibiotics, especially children
• UV is one of the ways to increase Vitamin D levels, even with poor kidney
• Just 2 doses of Vitamin D resulted in many benefits (Chronic Kidney Disease)
• Skin directly benefits from the sun – no liver, kidney needed to create Vitamin D
• Low Vitamin D when entering ICU is deadly (acute kidney injury in this case)
• Chronic Kidney Disease and Vitamin D Analogs – commentary
• Depression in Chronic Kidney Disease is predicted to be 6 times more likely if low vitamin D
• 7100 IU (50000 weekly) restored vitamin D levels for those with Chronic Kidney Disease
• 50 percent of Chronic Kidney Disease treatments in Germany include vitamin D
• Less Pneumonia in those having more activated vitamin D (kidneys working)
• Chronic Kidney disease in 20 percent of seniors in Taiwan
• Lung cells activate Vitamin D, without liver or kidney
• 4X fewer malignancies after kidney transplant if got active vitamin D – Prospective Score
• Low vitamin D associated with hemodialysis problems
• X-ray contrast agents can injure kidney in low vitamin D rats
• Vitamin D for kidney disease – use native or active form
• Vitamin D3 vs serum D3 (Calcitriol, HyD)
• End stage kidney disease almost 3X more likely for blacks – 2009
• Kidney stone production REDUCED in rats when Vitamin D and Calcium was added
• Skin can create and activate vitamin D – kidney not needed
• Immune system and vitamin D (from kidney doctor’s point of view)
• Kidney failure – still debating what form of vitamin D to use
• Kidney stones (Calcium) associated with lower vitamin D this time
• Kidney stones independant of vitamin D levels in range 20-100 ng
• Psoriasis is associated with kidney disease, heart problems, diabetes, etc
• Chronic Kidney Disease not treated by 1400 IU of vitamin D
• Kidneys, Vitamin D and Calcium
• Yet again, 1 gram of Calcium increases Kidney stones with vitamin D
• Every child with kidney problems (ideopathic nephrotic syndrome) had low vitamin D
• Chronic kidney with low vitamin D: 90 percent of pediatric nephrologists now recommend more D
• Magnesium reduced calcitriol (active vitamin D) artery calcification in CKD by 50 percent
• Hemodialysis low vitamin D status was normalized with 28500 IU avg daily
• With CKD should measure the active form of vitamin D
• Active vitamin D treats Chronic Kidney Disease by stimulating Klotho production
• Not as much active vitamin D if poor kidney function and low vitamin D
• Kidney Cancer differences with skin color probably due to vitamin D differences
• Vitamin D, the autonomic nervous system, and cardiovascular risk - Editorial
• Itchy skin (pruritus) due to kidney disease was treated with topical vitamin D
• Dialysis patients need real vitamin D – Editorial
• Some form of vitamin D may be the lowest cost treatment for CKD – Spanish
• Vitamin D status unrelated to fractures with Kidney disease (should not be a surprise) – 2015
• Vitamin D and bicarbonate perhaps synergistically reduce muscle loss
• 1700 IU of vitamin D not enough to help hemodialysis patients
• 25,0000 IU vitamin D weekly only raised 60 percent on hemodialysis above 30 ng
• Table of outcomes for seniors vs vitamin D level
• Vitamin D and chronic kidney disease
• Blacks have low vitamin D and have 50 percent more kidney failure
• Kidney failure and vitamin D deficiency vicious cycle
• Vitamin D level can be high, but little benefit: due to kidney, genes, low Magnesium etc.
• Preterm infants, kidney, rickets and vitamin D intake: is it time for rewriting the history
• Vitamin D and Chronic Kidney Disease
• Vitamin D receptor activation and Chronic Kidney Disease
• Application to FDA for use of active Vitamin D for hemodialysis patients
• Chronic Kidney Disease patients need more vitamin D and phosphate
• Vascular calcification in chronic kidney disease
• Most Chronic Kidney Disease patients restored their vitamin D levels with just 1,000 IU
• Kidney patients need some form vitamin D – the question is, which form
• 2000 IU vitamin D3 was not enough for children with chronic kidney disease
• Protective cardiovascular and renal actions of vitamin D and sex hormones
• Chronic Kidney Disease clinical trials of UV in Germany
• Vitamin D3 far better than D2 for hemodialysis
• Virtually all black dialysis patients with low albumin are vitamin D deficient in the winter
• Dialysis patients with less than 15 ng of vitamin D did not feel well
• Paricalcitol better than vitamin D2 for Chronic Kidney disease
• Postmenopausal vitamin D benefits to blood pressure and kidney – Review
• Comparing Vitamin D and analogs for kidney patients
• Vitamin D tester falsely said half of hemodialysis patients had less than 30 ng
• Telomeres longer for dialysis patients having higher levels of vitamin D
• Death from acute kidney injury 84 percent more likely if have low vitamin D
• Vitamin D and Kidney Disease - 2009
• Kidney disease requires magnesium
• For those with kidney disease, diabetes is strongly associated with low vitamin D – 2012
• Chronic Kidney disease and low vitamin D in disadvantaged populations
• Lack of cubilin in kidney decreases vitamin D in the body
• CYP24A1 gene, kidney disease, and vitamin D
• Chronic Kidney – only 1 in 3 doctors said kids need more than 30 ng of vitamin D
• 5700 IU of vitamin D helped half with chronic kidney disease if not having dialysis
• Chronic kidney disease associated with higher levels of vitamin K1
• Chronic kidney disease and PTH – Calcium – Phosphate – Vitamin D
• Kidney Conference had many Vitamin D papers
• Perhaps Vitamin D3 is better than D2 for Chronic Kidney Disease
• Chronic Kidney disease with low vitamin D causes health problems
• Seniors with poorly functioning kidneys had lower levels of vitamin D
• Chronic Kidney Disease stage not associated with vitamin D levels
• Some children with kidney disease cannot stand too much vitamin D
• Clinical measures identify vitamin D deficiency in dialysis
• Death rate increased 3X for chronic kidney disease if low vitamin D
• Kidney aging-inevitable or preventable
• Use of vitamin D in chronic kidney disease patients.
• 33 percent more likely to die of chronic kidney disease if less than 15 ng vitamin D
• People with kidney disease moved faster after adding vitamin D
• Hydroxylated vitamin D goes away faster than standard D in Kidney patents
• Cyclosporine etc. probably increase the need for vitamin D
• Kids with new kidneys were both short and low on vitamin D
• Wearable dialysis device being tested which also converts vitamin D
• Kidney and Vitamin D – Heaney
• Chronic Kidney disease and vitamin D deficiency
• Editorial on Vitamin D deficiency– Current Drug topics
• Cochrane review finds that Vitamin D helps with kidney
• D3 increased blood levels but doxercalciferol (an artificial D3) did not