Severe sleep apnea increased chance by 4.8 X of cancer death: low vitamin D

Sleep Apnea Tied to Increased Cancer Risk NYT May 2012

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University of Wisconsin School of Medicine and Public Health

. . over 22 years, found that severe breathing problems at night increase the likelihood of dying from cancer by 4.8 times, compared to people who had no such breathing issues.

People with moderate apnea were found to have double the risk of dying .

Spanish Sleep Network,

Following 5,200 people over seven years, the study tracked oxygen depletion and found, for example, that people whose oxygen levels dipped below 90 percent, for up to 12 percent of the total time asleep, had a 68 percent greater likelihood of developing cancer , than people who did not have breathing difficulties at night.

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The past has shown that

• Sleep apnea is associated with low vitamin D

• Sleep apnea is associated with obesity, which is also associated with low vitamin D

• Sleep apnea is associated with diabetes, which is also associated with low vitamin D

• Sleep apnea is associated with hypertension, which is also associated with low vitamin D

• Sleep apnea is associated with heart attacks and strokes, which are also associated with low vitamin D

  • Example: Sleep Apnea and heart attack clinical trial
• Cancer is associated with low vitamin D

This article adds the following: Sleep apnea is associated with dying of Cancer

Hypothesis: Sleep Apnea association with Cancer is due to low vitamin D, not low level of oxygen.

Diseases which become related due to vitamin D deficiency has the following graphic and references

• Associations seen so far (as of 2011)

• Statins ==> many diseases associated with low vitamin D   update Jan 2012

• Parkinson's ==> osteoporosis

• Skin wrinkles ==>fragile bones

• Dental problems==> depression (pregnancy)

• Pregnancy ==> dental problems

• Smoking ==> weak bones

• Prostate Cancer ==> Osteoporosis

• No molar ==> 12X increase in Breast Cancer

• Obesity ==> Diabetes

• Diabetes ==> Rheumatoid Arthritis

• Low vitamin D for various reasons ==> 9X Suicide

• Immune System disease (CVID) ==> osteoporosis

• Psorasis ==> Metabolic Syndrome on the web

Predicted possible associations (not yet reported)

• Watching TV or reading books ==> myopia

• Lung cancer ==>

• HIV ==>

• Diabetes ==> Depression

• Surgery ==>cognitive problems which last for many months

• Disease ==> Insomnia

• Several diseases now associated with aging (but may be due to low vitamin D) ==>cognitive decline

• US truckers die 16 years earlier - partially due to vitamin D deficiency

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See also web

• Other diseases associated with sleep apnea
  • Diabetes, Gastroesophageal Reflux Disease (GERD), Polycystic Ovary Syndrome (PCOS) 30X association, Chronic Problems in the Upper Airways, Atrial Fibrillation
  • Pulmonary hypertension, Kidney failure, Peripheral nerve damage, Seizures, epilepsy, and other nerve disorders. Headaches, Eye disorders,

• Is obstructive sleep apnea associated with ADHD? Aug 2011

• Truckers have problems with Sleep Apnea as well

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Additional references provided by Dr. Grant

• Bozkurt NC, Cakal E, Sahin M, Ozkaya EC, Firat H, Delibasi T. The relation of serum 25-hydroxyvitamin-D levels with severity of obstructive sleep apnea and glucose metabolism abnormalities. Endocrine. 2012 Jun;41(3):518-25.

• Grant WB. Ecological studies of the UVB–vitamin D–cancer hypothesis; review. Anticancer Res. 2012;32(1):223-36. in VitaminDWiki