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Do not test UK pregnancies for low vitamin D (since 800 IU does not help) – Nov 2016

Should routine screening for vitamin D deficiency be performed in pregnancy?

Evidence-Based Practice Evidence-Based Practice Vol. 19 | No. 11 | November 2016
Abstract Should routine screening for vitamin D deficiency be performed in pregnancy?
Evidence-based answer: No. Low vitamin D levels in pregnancy are associated with worse outcomes than no vitamin deficiency; however, supplementation does not conclusively improve outcomes (SOR: B, meta-analyses of observational studies and RCTs). The Royal College of Obstetricians and Gynaecologists (RCOG) recommends against screening for vitamin D deficiency in pregnancy (SOR: C, expert opinion)

VitaminDWiki

The 2014 meta-analysis which they based their decision on generally used 800 IU of vitamin D
137 health problems associated with low vitamin D – meta-meta-analysis April 2014
Over 400 studies of Vitamin D during pregnancy have only rarely found a benefit at 800 IU.
Good benefits start at 4,000 IU – 5 times large dose than what the meta-analysis considered
If this had been aspirin instead of vitamin D the conclusion could have been:
Do not bother testing for headaches if you are only going to prescribe 1/5 of a tablet of aspirin, such a low dose does not help headaches

See also VitaminDWiki

Healthy pregnancies need lots of vitamin D has the following summary

Problem
ReducesEvidence
0. Chance of not conceiving3.4 times Observe
1. Miscarriage 2.5 times Observe
2. Pre-eclampsia 3.6 timesRCT
3. Gestational Diabetes 3 times RCT
4. Good 2nd trimester sleep quality 3.5 times Observe
5. Premature birth 2 times RCT
6. C-section - unplanned 1.6 timesObserve
     Stillbirth - OMEGA-3 4 timesRCT - Omega-3
7. Depression AFTER pregnancy 1.4 times RCT
8. Small for Gestational Age 1.6 times meta-analysis
9. Infant height, weight, head size
     within normal limits
RCT
10. Childhood Wheezing 1.3 times RCT
11. Additional child is Autistic 4 times Intervention
12.Young adult Multiple Sclerosis 1.9 timesObserve
13. Preeclampsia in young adult 3.5 timesRCT
14. Good motor skills @ age 31.4 times Observe
15. Childhood Mite allergy 5 times RCT
16. Childhood Respiratory Tract visits 2.5 times RCT

RCT = Randomized Controlled Trial

Pregnancy category starts with

719 items in Pregnancy category

 - see also

Meta-analyses of Pregnancy and Vitamin D


 Download the PDF from VitaminDWiki

Attached files

ID Name Comment Uploaded Size Downloads
7780 routine screening for vitamin D.pdf PDF 2016 admin 04 Mar, 2017 01:23 78.47 Kb 271
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