Vitamin D Intervention Clinical Trials - Feb 2013

Intervention = provide vitamin D and see if it prevents or treats a health problem
Most are Random Controlled Clinical Trials

See also VitaminDWiki

• Vitamin D intervention – 1204 clinical trials – May 2014 update
• Overview Evidence for vitamin D
• Proof that Vitamin D Works 24 health problems as of Feb 2013
• Can Observational Studies be as good as Random Controlled Trials for Vitamin D Feb 2013
  Interventions can be Observational Studies or Random Controlled Trials
• Evidence that the minimum vitamin D blood level is 30 ng – Grant Nov 2012
• Overview Vitamin D Intervention
• Hypothesis of Vitamin D and Diseases - and strength of evidence
• All items in category Vitamin D Evidence 60 items
• National Institute of Health - Strength of Vitamin D Evidence
• Evaluating the vitamin D evidence - Dr. Heaney Dec 2010 slide presentation
• Summary of Vitamin D trials - Grant Jan 2012
• Vitamin D also TREATS

Number of Invertention Trials listed in US

Intervene by giving vitamin D to some or all of the participants, then observe any resulting prevention and/or treatment

Intervention Trials listed at WHO

Newly listed at WHO for approximately previous 11 months ending Feb 2013
Vitamin D Levels in Patients With Central Retinal Vein Occlusion- a Prospective Controlled Study
Effect of low caloric diet with and without vitamin D supplementation in non alcoholic fatty liver
DIABGAD - Trial to Preserve Insulin Secretion in Type 1 Diabetes Using GAD-Alum (Diamyd) in Combination With Vitamin D and Ibuprofen
Vitamin D and Cardiac Autonomic Tone in Hemodialysis
Development of Non-invasive Method for Quantifying Vitamin D Levels in the Body Using Spectroscopy
Vitamin D supplements to prevent depression and poor physical function in persons over 60 years
The Effect of Inactive and Active Vitamin D on Serum Sclerostin/dickkopf1 Levels
Assessing the Effects of Alfacalcidol Intake on Expression of Involed Gene in Metabolism in Obese Subjects
EFFECT OF VITAMIN D3 SUPPLEMENTATION ON INSULIN SENSITIVITY IN PREDIABETES.
Vitamin D and Mammographic Breast Density
Vitamin D Treatment and Hypogonadism in Men
DO-HEALTH / Vitamin D3 - Omega3 - Home Exercise - Healthy Ageing and Longevity Trial
Effect of vitamin D supplementation on primary hypertension: a randomized clinical trial
Vitamin D Supplementation in Patients With Diabetes Mellitus Type 2
The Genetics Behind Vitamin D Status (VitDgen)
Vitamin D for Women at Increased Risk of Developing Ovarian, Fallopian, or Primary Peritoneal Cancer
Comparison of the efficacy of two regimens of Vitamin D supplementation in preventing vitamin D deficiency among preterm infants.
Effect of Vitamin D Supplementation on Endothelial Function in Obese Adolescents
A clinical trial to evaluate combination of 4 cardiovascular drugs and aspirin and Vitamin D supplementation in subjects for cardiovascular diseases
Efficacy of oral Vitamin D therapy in children with Vitamin D deficiency
The effect of vitamin D supplementation in Non Alcoholic Fatty Liver Disease treatment
Duration of Vitamin D Stores After Prolonged Vitamin D Substitution
?Vitamin D as add-on treatment for relapsing-remitting multiple sclerosis: an unicentric, randomized, double-blinded, placebo-controlled clinical trial?
Effect of Vitamin D Supplementation on Glucose Tolerance in Subjects at Risk for Diabetes With Low Vitamin D.
Dose-related Effects of Vitamin D3 on Immune Responses in Patients With Clinically Isolated Syndrome
Gestational diabetes and vitamin D
Effect of High-Dose Vitamin D on Bone Density in Osteogenesis Imperfecta
Vitamin D3 in Pediatric SLE
a study to evaluate the role of vitamin-D supllementation in teatment of patints with type 2 diabetes
The effect of vitamin D on breast density in women older than 40 years
Postoperative treatment with Vitamin D for patients with a history of Bariatric Surgery in C and U County.
The effect of vitamin D supplementation on blood pressure in hypertensive patients with vitamin D deficiency
A Randomized, Parallel, Double-blind, Placebo-controlled Study of Vitamin D as Prophylactic Treatment for Migraine
Immune Reconstitution in Tuberculosis Disease
Immune Reconstitution in HIV Disease (IREHIV)
Clinical Trial to Determine the Efficacy of Vitamin D for Acne Therapy
The Effect of Hypovitaminosis D and Vitamin D Supplementation on Fracture Nonunion Rates
Bioavailability of Vitamin D in Children and Adolescents With Crohn's Disease
The Effect of Oral Vitamin D Versus Narrow-Band UV-B Exposure on the Lipid Profile
DRISK Study
A Study of Vitamin D supplementation in breastfeeding young children
High Dose Preoperative Cholecalciferol Supplementation and Perioperative Vitamin D Status
Serum Vitamin D Levels and Peripheral Neuropathy Among Multiple Myeloma Patients
Effect of Vitamin D Supplementation on Coronary Calcification and Parathyroid Hormone in CKD Patients
Vitamin D In Older People
Pharmacokinetics of Vitamin D in Multiple Sclerosis and in Health
Immunological response of vitamin D
The effect of vitamin D on epilepsy
Vitamin D supplementation to reduce CardioVascular risk factors
Vitamin D as an add-on Therapy With Pegylated Interferon and Ribavirin for Chronic Hepatitis c
Effects of Vitamin D and Calcium Supplementation on Inflammatory Biomarkers and Adypocytokines in Diabetic Patients
A Phase 2A Dose-ranging and Pharmacokinetic Study of an Oral Vitamin D Compound (DP001) in Secondary Hyperparathyroidism
Pilot Trial to preserve residual insulin secretion in children and adolescents with recent onset Type 1 diabetes by using GAD-antigen (Diamyd) therapy in combination with Vitamin D and Ibuprofen .
Safety and Efficacy of CTAP101 Capsules to Treat Secondary Hyperparathyroidism in Stage 3 or 4 CKD and Vitamin D Insufficiency
Swiss Study on Vitamin D and Calcium in Nursing Homes
Vitamin D and Preeclampsia
Vitamin D, Cardiovascular Disease, and African Americans
Vitamin D, Steroids, and Asthma in African American Youth
vitamin D and calcium Supplementation reduces the complication of letrozole in breast cancer patients
25-Hydroxyvitamin D Levels and the Risk of Stroke
The International Polycap Study 3 (TIPS-3)
Optimising Vitamin D Status in Older People (VDOP)
Multicenter, randomized, double-blind, placebo controlled, parallel group trial to evaluate the effect of Vitamin D supplementation for fall prevention
Vitamin D3 Supplementation for Heart Failure Patients
Bone Health and Vitamin D Status
The VALDIATE-D Study
Vitamin D Loading Dose in Advanced Lung Cancer
Vitamin D Deficiency and Postoperative Hypocalcemia
Maternal Vitamin D Status and Neonatal Bone Strength
Sunlight Exposure and Vitamin D Status of Children of South Asian Ethnicity Living in the UK
Wheezing in Black Preterm Infants: Impact of Vitamin D Supplementation Strategy
Vitamin D Supplementation for Extremely Preterm Infants
Effect of Omega-3 Fatty Acid on Vitamin D Activation
To study the effects of CollagenCal? in the management of Osteoporosis in women.
Hepatitis immunisation and vitamin D supplementation
Vitamin D supplementation in the obese
Vitamin D Supplementation in Polymorphic Light Eruption
To study levels of calcium, phosphorous and vitamin in body fluids before and after a 12 weeks course of pioglitazone, an anti diabetic agent, in pateints with diabetes
Clinical Trial of Phenylbutyrate and Vitamin D in Tuberculosis (TB)
The effect of vitamin D on the glycemic control and non-alcoholic fatty liver disease
Testosterone Pellets Plus Vitamin D and E Versus Vitamin D and E Alone for the Treatment of Peyronie's Disease
Biochemical Efficacy and Safety Trial of vitamin D (BEST-D)
The Effect of Vitamin D Repletion in Patients With Hepatocellular Carcinoma on the Orthotopic Liver Transplant List
Vitamin D Supplementation in Overweight/Obese African American Adults and Youth (D-SUNNY)
Vitamin D During Pregnancy
Is Treatment of Vitamin D Deficiency Associated With Resolution of Statin-Induced Muscular Symptoms
The effect of Friso Premature on growth, sleep characteristics, Nutritional status parameters and inflammatory markers.
Cholecalciferol and Flu Vaccine in Treating Healthy Participants
Effect of Vitamin D supplementation in HIV-infected children, adolescents and young adults with hypovitaminosis D.
Optimizing Vitamin D in the Elderly
Randomized double-blind intervention trial to assess the efficacy of vitamin D3 supplementation vs placebo in reducing hepatic steato-inflammation and cardio-metabolic
  risk profile in patients affected by type 2 diabetes and non-alcoholic fatty liver disease (NAFLD/NASH)
Vitamin D supplementation in polymorphic light eruption: Randomized double-blinded placebo-controlled trial - Vitamin D and PLE
Study to evaluate the pharmacokinetic of vitamin D in patients with obesity after bariatric surgery
The efficacy and safety analysis of Peg-IFN/RBV/Vitamin D3 therapy for liver cirrhosis with hepatitis c persistent infection: RCT Study
Effect of Bazedoxifene to osteoporotic patients under active vitamin D treatment
Metabolic Syndrome and Insulin Resistance at Allina
Efficacy of Different Regimens of Vitamin D Supplementation in Preterm Infants- A Randomized Double Blind Trial
Phase III Clinical Trial of DP-R206 and Bonvia In Postmenopausal Women With Osteoporosis
Impact of Vitamin D Supplementation on Cardiometabolic Risk Factors [The Daily D Health Study]
Open Label Clinical Trial of Vitamin D in Children With Autism

UK etc

22 Clinical Trials as of Feb 2013

EU

222 Clinical Trails as of Feb 2013

India

no vitamin D trials listed Feb 2013

Australia/NZ

no vitamin D trials listed Feb 2013

Japan etc

52 for Vitamin D (do not use quotes = "Vitamin D")
Has options to search elsewhere in the world, but they do not appear to work

Germany

7 vitamin D intervention trials listed Feb 2013