High Dose Vitamin D Supplementation Is Associated With a Reduction in Depression Score Among Adolescent Girls: A Nine-Week Follow-Up Study.
J Diet Suppl. 2017 Jul 31:1-10. doi: 10.1080/19390211.2017.1334736. [Epub ahead of print]
Depression has been found to be independently reduced by Vit D, Magnesium, Omega-3, and St. John's Wort in a variety of studies
Search Google for depression (gut OR digestion) 23,800,000 hits as of Sept 2017
- Example 1 Depression linked with bad digestion
- Example 2 Where There Is Mental Illness, There Is Poor Digestion
- It is likely that many of the depressed girls had poor guts and thus poor response to vitamin D.
- This study probably would have been much more successful if it had used a gut-friendly form of Vitamin D, for longer than 9 weeks, along with some combination of Magnesium, Omega-3, and St. John's wart
Vitamin D
- Depression category listing has
268 items along with related searches - Anti-depression medication about as good as big increase in vitamin D – meta-analysis of flawless data April 2014
- Much less depression if higher than 43 ng of vitamin D – Oct 2012
- Just 1500 IU of Vitamin D significantly helps Prozac – RCT March 2013
- Senior Depression and Vitamin D – review March 2016
Magnesium
- Depression is associated with low Magnesium – meta-analysis April 2015
- Depression greatly reduced by taking 250 mg of Magnesium Chloride daily for 6 weeks– RCT June 2017
Omega-3
- How Omega-3 Fights Depression – LEF July 2016
- Depression treated somewhat by Omega-3 (St. John's Wort better) – RAND org reviews 2015
- Depression substantially decreased with Omega-3 – Sept 2015
Note: Increasing Omega-3 increases the amount of vitamin D getting to the cells
Items in both categories Depression and Intervention:
- Depression cost-effectively reduced by 50,000 IU of Vitamin D monthly (Iranian teens) – July 2023
- Infants getting an additional 800 IU of vitamin D for 2 years had 60% fewer psychiatric symptoms at age 7 – RCT May 2023
- Anxiety and Depression decreased in senior prediabetics with weekly 25,000 IU of Vitamin D – RCT Sept 2022
- Depression decreased by Vitamin D (12th study in VitaminDWiki) – RCT Nov 2022
- Overweight needed more EPA (4 grams) to fight depression – RCT Aug 2022
- Omega-3 did not prevent depression (they failed to reduce Omega-6, which blocks Omega-3) – RCT Dec 2021
- Weekly Vitamin D plus daily Magnesium is great (reduced depression in obese women in this case) – July 2021
- Depression in psychiatric youths reduced 28 percent after just 1 month of vitamin D – RCT Feb 2020
- Yet another study confirms Depression is treated by weekly Vitamin D (50,000 IU)– RCT Dec 2019
- Depression decreased after vitamin D (50,000 IU weekly to elderly in the case) – RCT Oct 2019
- Vitamin D - no cure for depression (when you use only 1200 IU) – Aug 2019
- Depression reduced in Diabetics with 3 months of 4,000 IU of vitamin D – RCT July 2019
- Vitamin D treatment of diabetes (50,000 IU every 2 weeks) augmented by probiotic – RCT June 2018
- Women had better sexual desire, orgasm and satisfaction after Vitamin D supplementation – Feb 2018
- Vitamin D depression RCT canceled: too many were taking Vitamin D supplements, etc. Feb 2018
- Depression in adolescent girls reduced somewhat by 50,000 IU weekly for 9 weeks – July 2017
- Perinatal depression decreased 40 percent with just a few weeks of 2,000 IU of vitamin D – RCT Aug 2016
- Just 1500 IU of Vitamin D significantly helps Prozac – RCT March 2013
- Reduced depression with single 300,000 IU injection of vitamin D – RCT June 2013
- 40,000 IU vitamin D weekly reduced depression in many obese subjects – RCT 2008
- 50,000 IU Vitamin D weekly Improves Mood, Lowers Blood Pressure in Type 2 Diabetics – Oct 2013
Download the PDF from VitaminDWikiSubset of Table 4. Effects of vitamin D on depression scores.
Before After p value Mild depression 16 15 .002 Moderate depression 23 20 .001 Severe depression 33 26 .001 25 (OH) vitamin D 6.7 ng 35 ng .001
Bahrami A1,2, Mazloum SR3, Maghsoudi S4, Soleimani D5, Khayyatzadeh SS5, Arekhi S2, Arya A2, Mirmoosavi SJ6,7, Ferns GA8, Bahrami-Taghanaki H7, Ghayour-Mobarhan M9.Although vitamin D deficiency is known to be a risk factor for some psychological disorders, there have been few studies on the effects of vitamin D supplementation on their symptoms. Depression and aggression are common mental disorders and are associated with disability and disease burden. We aimed to evaluate the effectiveness of high-dose vitamin D supplementation on depression and aggression scores in adolescent girls. Nine hundred forty adolescent girls received vitamin D3 at a dose of 50,000 IU/week for 9 weeks. Anthropometric parameters and blood pressure were measured using standard protocols at the baseline and at the end of the study. Depression score was evaluated using the Beck Depression Inventory-II and aggression was evaluated using the Buss-Perry Aggression Questionnaire at baseline and at the end of the study. Comparison among the four categories of depression score (normal, mild, moderate, and severe) revealed no significant differences in demographic and anthropometric parameters at baseline. After 9 weeks of vitamin D supplementation, there was a significant reduction on mild, moderate, and severe depression score. However, vitamin D supplementation had no significant effect on aggression score. Our results suggest that supplementation with vitamin D may improve depressive symptoms among adolescent girls, as assessed by questionnaire, but not aggression score. Formal, larger, randomized controlled studies are required to confirm this effect on cases with different degrees of depression.
PMID: 28759290 DOI: 10.1080/19390211.2017.1334736
Depression in adolescent girls reduced somewhat by 50,000 IU weekly for 9 weeks – July 2017Printer Friendly Follow this page for updates7331 visitors, last modified 18 Sep, 2017, This page is in the following categories (# of items in each category)