Practical Vitamin D Supplementation Using Machine Learning
J Bone Metab. 2020 May;27(2):111-117. doi: 10.11005/jbm.2020.27.2.111
Tyler Fugere 1, Zhongning Jim Chen 1, Issam Makhoul 1
Women with breast cancer.
Wrongly considered than 20 ng was a high enough level of vitamin D
Need more to get to 30 ng of 40 ng
Need more if overweight or obese
Unclear how long for the vitamin D levels to plateau
There may be a on-line calculator - investigating
- One pill every two weeks gives you all the vitamin D most adults need
- Every 2 weeks Diabetes + Heart Failure + Chronic Pain + Depression + Autism + Breast Cancer + Colon Cancer + Prostate Cancer + Preeclampsia + Premature Birth + Falls + Cognitive Decline + Respiratory Tract Infection + Influenza + Tuberculosis + Chronic Obstructive Pulmonary Disease + Lupus + Inflammatory Bowel Syndrome + Urinary Tract Infection + Poor Sleep + Weight Loss + Growing Pain (22 problems)
18 additional Health Problems fought when taking 50,000 IU Vitamin D weekly
- 50,000 IU Vitamin D weekly provided enough benefit for combat sport athletes – March 2020
- Vitamin D supplementation guidelines (adults – 50,000 IU per week) – Feb 2017
- Authors: Pawel Pludowski, Michael F. Holick, William B., Grant, .... Sunil J. Wimalawansa
- AI: Exciting opportunity for Vitamin D Researchers
- Intervention - non daily category listing has
271 items along with related searches - Better than Daily category listing has
33 items along with related searches - IBS diarrhea treated by weekly 50,000 IU of Vitamin D – RCT March 2020
- Optimal vitamin D supplementation strategies (D3 - weekly or monthly) – Feb 2017
- VitaminDWiki pages containing "50,000" in title 163 as of Dec 2021
Download the PDF from VitaminDWiki
Background: Patients with breast cancer are at increased risk of developing osteoporosis. Maintaining normal levels of vitamin D may decrease the risk of osteoporosis, and vitamin D levels must be corrected in patients who develop osteoporosis before beginning bone modifying agents. Therefore, it is important to correct insufficient vitamin D levels in a timely manner. In clinical practice, current guidelines for replacement regimens often fail to rapidly correct vitamin D levels. The goal of this study was to review data in order to predict what replacement regimen(s) were most effective at repleting vitamin D levels.
Methods: For this retrospective cohort study, data was collected from medical records of 2,164 female patients with breast cancer with Institutional Review Board approval. Total level change per week was the primary outcome and was compared for the most commonly used vitamin D replacement regimens adjusted for age, race, body mass index, creatinine clearance, endocrine therapy, and initial level.
Results: Higher weekly doses of vitamin D supplementation had a more significant impact on the rate of correction compared to lower daily doses. Generalized linear model was used to develop an online calculator that predicts time to vitamin D level correction adjusted for significant patient characteristics for 5 common replacement regimens as well as no intervention.
Conclusions: When choosing a vitamin D replacement regimen for patients with vitamin D deficiency, we recommend clinicians use the online calculator to ensure that the chosen regimen will enable the patient to reach vitamin D sufficiency in a timely manner.
Title change made Aug 2021 caused the visitor count to reset.
There have actually been8081 visitors to this page since it was originally made
50,000 IU Vitamin D weekly was the most popular for Breast Cancer - May 2020(Cached) Printer Friendly Follow this page for updates6721 visitors, last modified 20 Jan, 2022, This page is in the following categories (# of items in each category)Attached files
ID Name Uploaded Size Downloads 13950 Predict chart.jpg admin 24 Jun, 2020 30.96 Kb 595 13949 Machine learning to predict Vitamin D.pdf admin 24 Jun, 2020 394.91 Kb 552 - Better than Daily category listing has