Loading...

Toggle Health Problems and D

Gut problems more likely if low vitamin D (IBD: 1.6, UC: 2.3) – meta-analysis Aug 2015

Association Between Inflammatory Bowel Disease and Vitamin D Deficiency: A Systematic Review and Meta-analysis.

Inflammatory Bowel Diseases: doi: 10.1097/MIB.0000000000000546
Del Pinto, Rita MD; Pietropaoli, Davide DDS, PhD; Chandar, Apoorva K. MBBS, MPH; Ferri, Claudio MD; Cominelli, Fabio MD, PhD

Background: Vitamin D plays a role in several immune-mediated diseases, but its association with inflammatory bowel disease (IBD) is unclear. We conducted a systematic review and meta-analysis to assess the association between IBD and vitamin D deficiency.

Methods: We searched electronic databases from inception to December 2014 for observational studies reporting the presence of vitamin D deficiency (defined as serum 25-hydroxycholecalciferol [25(OH)D] level of <=20 ng/mL) in IBD patients and having a control group without IBD. Odds ratios (ORs) were combined using a random-effects model. Meta-regression was performed using latitude as a moderator. Study quality was assessed using the Newcastle-Ottawa scale.

Results: Out of 816 citations, 14 eligible studies were identified, comprising 1891 participants (938 IBD cases and 953 controls). Meta-analysis showed that patients with

IBD had 64% higher odds of vitamin D deficiency when compared with controls (OR = 1.64; 95% confidence interval, 1.30-2.08; I2 = 7%; P < 0.0001).
Patients with ulcerative colitis had more than double the odds of vitamin D deficiency when compared with normal controls (OR = 2.28; 95% confidence interval, 1.18-4.41; I2 = 41%; P = 0.01).

Latitude did not influence the association between IBD and vitamin D deficiency (P = 0.34). Generalizability of our results might be limited as we summarized unadjusted ORs, because of nonavailability of adjusted ORs in individual studies.

Conclusions: IBD is significantly associated with having higher odds of vitamin D deficiency. Well-designed randomized controlled trials and longitudinal studies are needed to further explain the role of vitamin D in IBD pathogenesis and its therapy.

See also VitaminDWiki

Overview Gut and vitamin D
Meta-analysis of Vitamin D category listing has 667 items along with related searches

The TOP articles in Gut and Vitamin D are

Gut problems more likely if low vitamin D (IBD: 1.6, UC: 2.3) – meta-analysis Aug 2015

7406 visitors, last modified 31 Oct, 2015,

Printer Friendly Follow this page for updates

Links to this page
- Ulcerative Colitis significantly reduced by 480,000 IU loading dose of nano Vitamin D – RCT July 2019 Ulcerative Colitis relapse 25 percent more likely if vitamin D level is lower than 35 ng – June 2016 IBD in Canadian children increasing 7% per year - Nov 2016

This page is in the following categories (# of items in each category)

Meta-analysis of Vitamin D 651 Gut 199

Edit

“One pill every two weeks fights diabetes, cancers, heart failure, and 21 other diseases.”

Click for details

Health Problems and D

15,500+ pages in VitaminDWiki
Topic (# in topic)

Acne (20+ studies)

Attention Deficit Hyperactivity Disorder/ADHD (52+)

Alcohol (29+)

Allergy (120+) Overview

Amyotrophic Lateral Sclerosis/ALS (30+)

Alzheimer's (81+) Overview

Ankylosing Spondylitis (20+)

Antibiotics/Probiotics (92+) Overview

Asthma (145+) Overview

Atopic Dermatitis Overview (18+)

Autism (163) Overview

Vit. D Receptor (14+)

Transgender (19+)

Autoimmune (204+)

Systemic Sclerosis (10+)

Back Pain (44+)

Lumbar Degeneration (14+)

Bipolar Disorder (16+)

Bone - Health (313+)

BMD, Bone loss (55+)

Breathing (453+)

Hay Fever (20+)

Pneumonia (50+)

Respiratory (82+)

Burns/Wounds (30+)

Cancer (293+) Overview

After diagnosis (113+)

Bladder (28+)

Bone (8+)

Breast (259+) Overview

Child (16+)

Colon (145+) Overview

Endometrial (5+)

Gastric (9+)

Leukemia (19+)

Liver (17+)

Lung (55+) Overview

Lymphoma (26+)

Mg and Cancer (13+)

Melanoma (43+)

Multiple Myeloma (10+)

Metastatic (17+)

Other (66+)

Ovarian (26+)

Palliative Care (10+)

Pancreatic (58+)

Prostate (103+) Overview

Skin (121+) Overview

Survive (37+)

Thyroid (7+)

Cardiovascular (529+) Overview

Atherosclerosis (56+)

Atrial Fibrillation (20+)

Heart Failure (47+)

HRV (10+)

Omega-3 (38+)

Statins (80+)

Carpal Tunnel Syndrome (12+)

Cerebral Palsy (6+)

Cholesterol (52+) Overview

Chronic Fatigue (7) Overview

Cognitive (389+) Overview

Anesthesia ==> Cog

Brain (103+)

Delirium (9+)

Dementia (50+)

Mental Illness (300+)

Mental Stress (10+)

Colds/flu Overview

Concussions (25+)

Chronic obstructive pulmonary disease/COPD (17+)

COVID-19 (1300+)

Cystic Fibrosis (52+)

Dental (116+)

Fluoridation (16)

Periodontitis (32+)

Depression (268+)

Anxiety ( 11+)

Omega-3 (29)

SAD (9)

Diabetes (551+) Overview

Hemodialysis (41+)

Magnesium (27+)

Meta-analyses (39+)

Metabolic Syndrome + Mg

Neuropathy (15+)

Prediabetes (30+)

Red Meat (4+)

Retinopathy (8+)

Type 1 Diabetes (46+)

Vitamin D Receptor (23+)

Zinc (5+)

Diseases general (93+)

Ear (17+)

Otitis Media (10+)

Endometriosis (8+)

Falls/Fractures (258+) Overview

Fatigue, Chronic Overview

Fertility/Sperm (142+)

Erectile Dysfunction (12+)

In Vitro Fert. (18+)

Testosterone (14+)

Fibromyalgia Overview

Fractures Overview

Ankle (16+)

Bone & Stress Fractures

Bone Mineral Density (28+)

Children (16+)

Hip Fractures (68+)

Vertigo (22+)

Genetics (343+)

CYP24A1 (31+)

CYP24R1 (25+)

CYP27B1 (62+)

Epigenetics (18+)

Telomere (12+)

Vit D Binding (177+)

Vit D Receptor (517+)

Cancer in VDR (79+)

Gestational Diabetes (34+)

Gout (13+)

Gut (207+) Overview

Bariatric (15+)

Celiac (7+)

Clostridium difficile (9+)

Crohn's (38+)

IBD (28+)

IBS (18+)

Ulcerative Colitis (12+)

Hair (20+)

Alopecia Areata (8+)

Health - general (109+)

Human Immunodeficiency Virus/HIV (45+) Overview

Hives (10+)

Hypertension (165+) Overview

Pregnancy (41+)

Hyperparathyroid Overview

Immunity (273+)

Inflammation (175+)

CRP (19+)

Infection (141+)

Influenza Overview

Kidney (230+) Overview

Chronic Kidney (63+)

Dialysis (39+)

Kidney Stones (29+) Overview

Leprosy (16+)

Liver (102+) Overview

Hepatitis-B (12+)

Hepatitis-C (13+)

NAFLD (27+)

Lyme Disease (9+)

Lupus (78+)

Mental Illness (20+)

Mental Stress (5+)

Metabolic Syndrome (106+) Overview

Mortality (296+)

Multiple Sclerosis (412+) Overview

Genetics and Receptor (32+)

Virus (16+)

Muscle (113+)

Handgrip (12+)

Sarcopenia (30+)

Muscular Dystrophy (9+)

Myopia (17+)

Obesity (442+)Overview

Child & Youth (60+)

Vitamin D Receptor (16+)

Virus and Obesity (25+)

Weight Loss (31+)

Osteoarthritis (61+) Overview

Knee (26+)

Osteoporosis (220+) Overview

BMD (26+)

Pain - chronic (167+) Overview

Magnesium (13+)

Pancreatitis (20+)

Parkinson's (117+) Overview

Pneumonia (22+)

Pollution (31+)

Pregnancy (920+) Overview

Breastfed (38+)

Caesarean (15+)

Depression (21+)

Dark Skin (30+)

Gestational Diabetes (41+)

In Vitro Fert. (18+)

Iodine (21+)

Low Birth Weight (23+)

Magnesium (30+)

Miscarriage (31+)

Multiple Sclerosis (13+)

Omega-3 before and during (49+)

PCOS (15+)

Preeclampsia (55+)

Preterm (125+)

Preterm - Omega-3 (13+)

Stillbirth (8+)

Prostate - BPH (16+)

Psoriasis (72+)

Respiratory Tract Infection/RTI (8+)

Restless Legs Syndrome (15+)

Rheumatoid Arthritis (117+) Overview

Juvenile RA (9+)

Rickets (127+) Overview

Sarcopenia (28+)

Schizophrenia Overview

Sepsis (201+)

Sickle Cell (20+) Overview

Skin (122+) Overview

Aging

Atopic Dermatitis(27+)

Hives

Vitiligo (8+)

Sleep (101+)

Sleep Apnea(12+)

Smoking (83+)

Spinal Cord (21+)

Spinal Surgery (13+)

Statins (40+)

Stroke (131+) Overview

Cognitive Impairment (15+)

Depression (9+)

Ischemic (21+)

Thyroid/Parath. (82+) Overview

PTH (34+)

Trauma/Surgery (352+)

Bariatric surgery (12+)

Bone surgery (23+)

ICU & Loading Dose (69+)

Need Vit D (69+)

Ortho. & Hip (69+)

Sepsis (41+)

Transplant (31+)

Traumatic Brain Injury (24+)

Tuberculosis (125+) Overview

Urinary Tract Infection (15+)

Virus (1400+)

All studies

Bird Flu

Cardiovascular (19+)

Cancers after VAX (17+)

Child - years after VAX (11+)

Cognitive (10+)

Dengue (27+)

Epstein-Barr Virus (20+)

Excess Deaths (23+)

Hepatitis (29+)

Herpes or Shingles (13+)

Ivermectin (35+)

Long-COVID (72+)

Magnesium (60+)

Masks (11+)

Meta-analyses (40+)

Omega-3 (14+)

Pfizer (20+)

RSV (12+)

Ultraviolet light (16+)

Vaccination (198+)

Vitamin D (650+)

Vitamin D Receptor (31+)

Vitamin K

Zinc (32+)

Vision (112+)

Cataracts (13+)

Diabetic Retinopathy (8+)

Dry Eye (12+)

Glaucoma (8+)

Macular Degeneration (20+)

Myopia (20+)

Uveitis (10+)

People and Low Vitamin D

Infant/Child (854+)

Allergy (36+)

Cancer (13+)

Cerebral Palsy (15+)

Down Syndrome (5+)

Fracture, low energy (10+)

Growing Pains (10+)

Pneumonia (25+)

Preemie (25+)

Puberty early if low D (9+)

Respiratory (21+)

RSV (25+)

Tonsils (9+)

Vaccination (10+)

Virus (42+)

Military (27+)

Veterans (17+)

Prisoners (14+)

Seniors (430+) Overview

Aging (38+)

Essential Tremor (4+)

Frailty (20+)

Longevity (47+)

Nursing Homes (19+)

Sarcopenia (25+)

Urinary incontinence (15+)

Vertigo (22+)

Skin - Dark (460+) Overview

Pregnancies (30+)

Sports (277+) Overview

Exercise (68+)

Muscle (138+)

Traumatic Brain Inj. (24+)

Women (196+) Overview

Endometriosis (25+)

Incontinence (16+)

Menopause (17+)

PCOS

Premenstrual Syndrome (20+)

Uterine Fibroid (13+)

Yeast Infection

Youth (175+)

Early Puberty (15+)

Locations

World (14+)

Aust NZ (68+)

Africa (28+)

Europe (233+)

India (65+)

Iceland (40+)

Middle East (154+)

Orient (77+)

Russia (12+)

Scotland (20+)

Far from Equator (124+)

Click here to search the site
A list includes 290+ pages having many studies
# of studies as of Dec 11, 2024
short URL for this page = is.gd/dhealth