Table of contents
- Vitamin D Supplementation and Allergic Diseases during Childhood: A Systematic Review and Meta-Analysis
- See in VitaminDWiki - Allergy - Overview Overview Asthma and Vitamin D
- VitaminDWiki -
80 studies in both categories Breathing and Infant/Child
Vitamin D Supplementation and Allergic Diseases during Childhood: A Systematic Review and Meta-Analysis
Nutrients 2022, 14(19), 3947; https://doi.org/10.3390/nu14193947
by Qinyuan Li et al ChinaWe performed a systematic review and meta-analysis to investigate the effects of vitamin D (VitD) supplementation on children with allergic diseases. MEDLINE, Embase, Web of Science, the Cochrane library, and three Chinese databases were searched up to 15 August 2022. Randomized controlled trials (RCTs) comparing a VitD supplementation versus a placebo for children with allergic diseases were included. Thirty-two RCTs with 2347 participants were included.
- VitD supplementation did not reduce the risk of asthma exacerbations in children compared with placebo overall (risk ratio (RR) = 0.84, 95% confidence interval (CI): 0.65 to 1.08, p = 0.18), but
- reduced the risk of asthma exacerbation in children with baseline serum 25(OH)D of <10 ng/mL compared with placebo (RR = 0.48, 95% CI: 0.28 to 0.83, p = 0.009).
- VitD supplementation significantly reduced Scoring Atopic Dermatitis or the Eczema Area and Severity Index scores in children with atopic dermatitis compared with placebo (standard mean difference = −0.5, 95% CI: −0.87 to −0.12, p = 0.009).
- VitD supplementation also reduced the symptom-medication score in children with allergic rhinitis compared with placebo (mean (standard deviation): 43.7 (3.3) vs. 57.8 (4.4), p = 0.001).
In conclusion, VitD supplementation did not reduce asthma exacerbation risk in children overall but may reduce asthma exacerbation risk in children with serum 25(OH)D concentration < 10 ng/mL. VitD supplementation reduces the severity of atopic dermatitis and symptoms of allergic rhinitis in children
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About half of the studies used <2,000 IU doses daily
Third study found that Infants needed 1600 IU of vitamin D – JAMA RCT May 2013
Need even larger doses for heavier (older) patients and those who are not healthy
See in VitaminDWiki - Allergy - Overview Overview Asthma and Vitamin D
VitaminDWiki -
80 studies in both categories Breathing and Infant/Child This list is automatically updated
- 3X reduction in respiratory infections in children taking more than 800 IU of Vitamin D weekly – Nov 2024
- Risk of childhood pneumonia reduced 30% by high Vitamin D - Oct 2024
- Bronchopulmonary dysplasia, in a third of preemies, 87% reduced risk for just 1 ng higher Vitamin D level – Oct 2024
- Infant respiratory distress reduced by Vitamin D – meta-analysis July 2024
- Vitamin D levels are low during Recurrent Wheezing - Feb 2024
- Obese asthmatic children Vitamin D - 50,000 IU then 8,000 IU daily - RCT Jan 2024
- France has injected 200,000 infants with RSV vaccine, based on no long-term data - Here we go again - Dec 2023
- Respiratory infections in children 6 X more likely if low Vitamin D (avg of 2 studies) - Aug 2023
- Prevention of allergies, eczema, asthma, in children – Vitamin D during pregnancy is a principal solution – July 2023
- Respiratory infection, children and Vitamin D - many studies
- Asthma by age 7 if wheezing before preschools and poor vitamin D Receptor - May 2023
- 3% fewer respiratory problems in children if single 100K vitamin D in 3rd trimester – May 2023
- Chronic tonsillitis virtually eliminated in children by Vitamin D (50,000 IU weekly) – RCT May 2023
- RSV kills 100,000 children annually around the world (Vitamin D can help)– May 2022
- Small doses of Vitamin D do not reduce childhood breathing allergies – meta-analysis Oct 2022
- Vitamin D reduces childhood allergic airway diseases (confirmed by metabolomics this time) – May 2022
- Wheezing and asthmatic children have weaker Vitamin D responses - May 2022
- Croup (due to viruses) has surged with Omicron - March 2022
- Allergy medications may be improved by Vitamin D (6X for birch pollen in this case) – Aug 2021
- Infant Respiratory Infections not reduced by mothers taking small amount of vitamin D (28,000 weekly)– RCT July 2021
- Recurrent RTI treatment success: Conventional 71 pcnt, Vitamin D 96 pcnt – March 2021
- The 6 percent of infants hospitalized for ARI are 2.2 X more likely to be Vitamin D deficient – April 2021
- Acute pneumonia in children 3X less likely if greater than 30 ng of vitamin D – Jan 2021
- Preemie Respiratory Distress Syndrome is 5X more likely if low vitamin D – Dec 2020
- Recurrent Wheezing in children is associated with low Vitamin D – several studies
- Respiratory viral infection (RSV) and low vitamin D - many studies
- Lower Respiratory Tract Infection in Infants reduced 5.9 X by daily 600 IU of vitamin D (China) - March 2020
- Gene that predicts wheezing is associated with low vitamin D – Oct 2019
- Bronchiolitis in children associated with both pollution and low solar – July 2019
- Allergic Rhinitis in infants treated by 1,000 IU vitamin D daily – June 2019
- Asthmatic children 5X more likely to have a poor Vitamin D Receptor – June 2019
- Babies 3.6X more likely to go to hospital for asthma if asthmatic mother had low vitamin D while pregnant – June 2019
- Childhood Asthma somewhat reduced by 2400 IU vitamin D late in pregnancy (néed more, earlier) March 2019
- Respiratory Distress Syndrome in preemies 5 X more likely if poor vitamin D receptor – Feb 2019
- Black infant recurrent wheezing rate dropped from 42 percent to 31 percent with just 400 IU of vitamin D – RCT Dec 2018
- Asthma in child 2.3 X more likely if both parents asthmatic (unless add Vitamin D) – VDAART Nov 2018
- Immature lungs in immature newborns – Vitamin D helps – Sept 2018
- Bronchiolitis had 1.3 X longer hospitalization if low Vitamin D (1016 infants) – Sept 2018
- Pneumonia in Egyptian Children 3.6 X more likely if poor Vitamin D Receptor – Aug 2018
- Childhood pneumonia not treated by 100,000 IU of vitamin D – Cochrane (need more, inhaled) – July 2018
- Pneumonia is increasing (now 1 in 6 child deaths), more vitamin D studies needed – June 2018
- Childhood Respiratory Health hardly improved with 600 IU of vitamin D (need much more) – May 2018
- Indoor pollution is a problem with obese black asthmatic children – May 2018
- Both parents smoke – child’s vitamin D level was 30 percent lower and worse asthma – May 2018
- Allergic rhinitis in children reduced somewhat during pollen season by just 1,000 IU of vitamin D – RCT Jan 2018
- Half the risk of Influenza -A in infants taking 1200 IU of vitamin D for 4 months – RCT Jan 2018
- Rapid newborn breathing (transient tachypnea) associated with low vitamin D – Dec 2017
- Preemies with poor lungs (Respiratory distress syndrome) have low levels of vitamin D – Nov 2017
- Risk of infant Asthma cut in half if mother supplemented Vitamin D to get more than 30 ng – RCT Oct 2017
- Respiratory infection in infant was 7 X more likely if low cord Vitamin D – March 2017
Small doses of Vitamin D do not reduce childhood breathing allergies – meta-analysis Oct 2022Printer Friendly Follow this page for updates1889 visitors, last modified 18 Oct, 2022, This page is in the following categories (# of items in each category)