It is IMPORTANT to have cofactors when taking more than 2000 IU vitamin D average
- Decrease Calcium and Increase Magnesium when increasing vitamin D
- There is a lack of evidence of the interactions - the following are guesses based on incomplete information
Most studies are monotheraputic: e.g. supply Vitamin D, and rarely use any of the cofactors
Update 2022 taking most of my supplements as pills - average of about 3/day
Also take Magnesium Chloride as a liquid and Omega-3 as a cream
__Update 2018 - taking many supplements in ((Bulk supplementation of Vitamin D, Magnesium, Zinc, B-12, K2, Boron etc. - lower cost and
Supplements which the Founder of VitaminWiki takes - as of Aug 2017
Cofactor | How Much | Benefit Bone teeth, nails | Comments | Actual supplementation by admin of VitaminDWiki | Cents per day | |||
Calcium | <750mg | Yes | Is excess calcium harmful to health - 2010 | 0* = None: get from healthy food | 0 ¢ | |||
Magnesium | 100mg (element) | Yes | May increase response to Vitamin D by 30% Many other health benefits as well | 1/2 teaspoon of Magnesium Chloride ever 3 days Make it by adding hot water to bulk MgCl (1 to 1) also use topically on both knees nightly | ~2 ¢ | |||
Vitamin K2 | >100 ug | Yes | perhaps 100 ug/1000 IU of vitamin D | Super K - all three forms in 1 capsule | 20 ¢ | |||
Vitamin A | ? | maybe | need some, but too much is bad | 0* | 0 | |||
Boron | 10 mg | Yes | may increase D3 in blood by 25% | Daily in granola in the morning | 1 ¢ | |||
Silica | ? | Yes | Daily - Horsetail - buy in bulk Include in morning cereal | 1 ¢ | ||||
Omega-3 | 1 g or 1 Vectomega tablet | By increasing Vitamin D | helps health A LOT May increase active D | 1 Vectomega daily - VERY bioavailable | 75 ¢ | |||
Zinc | ? | ? | Needed by Vitamin D Receptor Thus results not seen in Vitamin D tests | take 30 mg tablet or liquid weekly | 3 ¢ | |||
Following are NOT cofactors | ||||||||
Poly fats | Ratio of types of fat | no | Almonds have the best fat ratio and they have Magnesium | daily mixed nuts | 5 | |||
Water | 2.5 liters/quarts | No | Help flush kidneys of any excess Calcium Perhaps only need this much Water if >10,000 IU | >1 quart per day, filtered | 0 | |||
Iodine | ?? micrograms | No | many people are deficient recently I am currently researching the topic | ~600 micrograms once a week | ~1¢ | |||
Sun | How much time varies with skin type, age, latitude, clothing, stand/lie . . | Yes | Probably better than vitamin D supplements | 30 minutes sun-nap 80 days/year UVB lamp in the winter | 0 | |||
Vitamin D | 2,000-15,000 | Yes | Proven to prevent/treat 76+ diseases | 12,000 IU avg - Winter (50,000 every 4 days) 10,000 IU avg - Summer 50,000 every 5 days) | 6 5 |
Update 2015 - Good Health is more than Vitamin D and cofactors – my view
Magnesium is probably the most important cofactor
- Virtually everyone around the world has become Magnesium deficient in the past 50 years
Magnesium is second only to Vitamin D if the % of people who are deficient - What appears to be an allergic reaction to vitamin D is often due to a lack of Magnesium
- Having more Magnesium increases vitamin D bio-availability
- Magnesium comes in many forms - with a wide range of bioavailablity - Magnesium Chloride form seems to have the best bioavailability
- Magnesium and vitamin D - wide variety of information: test for Mg requires a $700 cell test
- Recommended levels of vitamins and minerals - history RDA DRI how much Vitamin A, D, Calcium, Magnesium, Boron, etc.
- Vitamin D3 and many co-factors in one pill
Notes as of April 2013
- It is OK to take lots of vitamin D for a month or two (Even 50,000 IU daily for a month)
- The first cofactor to consider to take would be Mg - as <1% of people get allergic reactions to vitamin D due to being very low on Mg
- Cofactors in a nutshell: Calcium 500, Magnesium 500, Vitamin K-2 100 (or more)
- Probably the milligrams of most cofactors, as well as IU Vitamin D, should vary with the weight
Looked at more than 100 suppliers of vitamin D liquid and solid co-factors Dec, 2010 - Feb 2011
- Daily dose sometimes < 30 cents
Adequate amount of most co-factors and LOW cost:
SOLID: 2 or 3 pills per day: Strontium Osteo, ABC to Z (2x), etc. for about 35 cents per day
LIQUID: Osteo Density: 21 cents per day
SOLID summary
This is a small portion of the spreadsheet (attached at bottom of this page)
None of the solid (or liquid) co-factors are perfect
Jarrow Bone-Up ULTRA has 2X more vitamin D3 and vitamin K2 than the non ultra version - continues to lack vitamin A
Vitamin A can perhaps be skipped (get it in food), or is very low cost to get as a separate pill
LIQUID Summary CLICK HERE for details on another page
The lowest cost, Osteo Density, also happens to have a fairly good set of co-factors
Units* | Trimedica | Source of Life | Osteo Density | OsteoCalm | Liquid Multi | Ionic Fizz | Good Amt. | |
Calcium | mg | 1200 | 250 | 750 | 367 | 600+ | 250 | 1300** |
Magnesium | mg | 600 | 125 | 300 | 133 | 300 | 300 | 400 |
Vitamin K | mcg | - | 150 | 100 (K1) | 67 (K2) | 80 | 45 | 120 |
Vitamin A | IU | - | 10,000 | - | 5000 | 200 | 250 | 3000 |
Boron | mcg | 50 | - | 2000 | 1000 | 1000 | 500 | 4000 |
Silica | mg | - | - | 100 | 2 | - | 60 | - |
Strontium | mg | - | - | - | 100 | - | - | - |
Daily cost | cents | - | 81 | 21 | 72 | 72 | 42 | - |
* Units of measure: mg = milligram = 0.001 gram, mcg = microgram = 0.000,001 gram, IU = International Unit
** 1300 mg Calcium only if taking less than 2000 IU of vitamin D, much less Calcium otherwise
POWDER
- Ionic Fizz Swanson $25 15 oz 60 servings per package $0.42 per day
CLICK HERE for Fizz ingredients on another page
See also VitaminDWiki
- How much vitamin D and other nutrients do I take Vit A, C, D3, K2: Mg, Iodine, Sulfate, . .
- Overview Calcium and vitamin D
- All items in category Calcium and vitamin D
228 items - Overview Magnesium and vitamin D
- All items in category Magnesium and vitamin D
368 items - Vitamin K and Vitamin D
- All items in category Vitamin K and vitamin D
156 items - All items in category Supplementing vitamin D
106 items - Review of nutrients for bone health – 2012 with author's recommendation for each
- 5000 IU Vitamin D3 with some co-factors expensive but simple, Added April 2012
- It takes more than just Vitamin D to build bones Blog post - March 2012
- Nutrients for Bone Health - 2006
- Vitamin D and Vitamin K for bones and heart - LEF Sept 2010
- 10,000 IU vitamin D plus 1200 mg Calcium MS trial April 2010
- Postmenopausal women should supplement vitamins C D K and Calcium – June 2010
- Boron increases vitamin D in the blood 24% increase with just 6 mg/day
- 10 mg of Boron daily increased Vitamin D and other levels – Dec 2010 does not say how much vitamin D level increased
- Recommended levels of vitamins and minerals - history RDA DRI including vitamins A and K, Calcium and Magnesium
- Masterjohn on relationships between Vitamin A D and K – Dec 2010
- When taking vitamin D, be sure to also take some vitamin A – Nov 2011
- Vitamin K2 is a vitamin D co-factor includes Dr. Colgan Strong Bones: Calcium, Magnesium, Strontium, Silicon, Boron Vitamins K and D3
- Calcium citrate and more than 800 IU of vitamin D to treat Osteoporosis – Mar 2011
Includes problems with excess Calcium at end of page- How you might double the benefit of your vitamin D
co-factors, take vitamin D in evening, right form/kind of vitamin D, . . . .- Hypothesis: increased breast cancer if not enough magnesium – Sept 2010
- Healthy bones need Ca, Silicon, Vitamins B, C, D, and K – Dec 2012
- Need to adjust cofactors if take 50,000 IU of vitamin D weekly – Nov 2013
- Vitamin D bioavailability: State of the art – Oct 2014
- Must balance co-factors when increasing vitamin D has the following graph
See also web
- Co-factors June 2012 includes many links, including mineral balancing
- Zinc—One of the Best Supplements to Help Fight Cold and Flu Mercola Dec 2012
Deficiency due to monocropping, ACE inhibitors, thiazide diuretics, and acid-reducing drugs, diets low in bioavailable zinc and high in phytic acid - Zinc Mercola Sept 2013
12% of Americans do not get minimum, and perhaps 40% of seniors, also some % of vegitarians (best bioavailable zinc comes from meat)
used to get enough from food - but not much is lost in the food chain, including initial plant growth
many easy tests for low zinc, including a taste test in your home (quick look at internet - take a Zinc Sulfate solution, and if you do not notice bitter taste you do not have enough zinc) - Poor Vitamin D Absorption Is Usually Not the Problem Easy Immune Health July 2014?
Vitamin K, Vitamin A, Magnesium, Calcium - it also has the following graphic
CLICK HERE for LIQUID details
SOLID details in spreadsheet and RTF files attached to the bottom of this page
short URL for this page = http://is.gd/cofactors
See also ZINC
- Zinc and Vitamin D category listing has
89 items along with related searches - Comment by a person: The Vit D Receptor has a tiny zinc finger on the end of it, so if we don't get enough zinc we can't activate our VDR's
Cofactors from a single source - $1.40/day - Found May 2015
Bone Renewal Amazon
$40 for 30 days os serviings (5)- 2 breakfast, 3 dinner
Low cost cofactors for vitamin D146417 visitors, last modified 31 Jul, 2023, This page is in the following categories (# of items in each category)Attached files
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