Loading...
 
Toggle Health Problems and D

Omega-3 helps muscles – Aug 2019

The Influence of Omega-3 Fatty Acids on Skeletal Muscle Protein Turnover in Health and Disease

Front. Nutrition doi: 10.3389/fnut.2019.00144
Chris McGlory1*, Philip Calder2 and Everson A. Nunes3
1 McMaster University, Canada
2 University of Southampton, United Kingdom
3 Federal University of Santa Catarina, Brazil

VitaminDWiki

Items in both categories Omega-3 and Sports are listed here:



Vitamin D and Omega-3 category starts with

409 Omega-3 items in category Omega-3 helps with: Autism (7 studies), Depression (28 studies), Cardiovascular (34 studies), Cognition (52 studies), Pregnancy (44 studies), Infant (34 studies), Obesity (14 studies), Mortality (7 studies), Breast Cancer (5 studies), Smoking, Sleep, Stroke, Longevity, Trauma (12 studies), Inflammation (18 studies), Multiple Sclerosis (9 studies), VIRUS (12 studies), etc
CIlck here for details

 Download the PDF from VitaminDWiki

Image

Image


Ingestion of omega-3 fatty acids is known to exert favourable health effects on a number of biological processes such as improved immune profile, enhanced cognition, and optimised neuromuscular function. Recently, data have also emerged demonstrating a positive influence of omega-3 fatty acid intake on skeletal muscle. For instance, there are reports of clinically-relevant gains in muscle size and strength in healthy older persons with omega-3 fatty acid intake as well as evidence that omega-3 fatty acid ingestion alleviates the loss of muscle mass and prevents decrements in mitochondrial content during periods of muscle-disuse. Cancer cachexia that is characterized by a rapid involuntary loss of lean mass, has also been shown to be attenuated by omega-3 fatty acid provision.
The primary means by which omega-3 fatty acids alter positively impact skeletal muscle mass is via incorporation of eicosapentaenoic acid (EPA; 20:5n-3) and docosahexaenoic acid (DHA; 22:6n-3) into membrane phospholipids of the sarcolemma and intracellular organelles. Enrichment of EPA and DHA in these membrane phospholipids is linked to enhanced rates of muscle protein synthesis, decreased expression of factors that regulate muscle protein breakdown, and improved mitochondrial respiration kinetics.
However, exactly how incorporation of EPA and DHA into phospholipid membranes alters these processes remains unknown. In this review, we discuss the interaction between omega-3 fatty acid ingestion and skeletal muscle protein turnover in response to nutrient provision in younger and older adults. Additionally, we examine the role of omega-3 fatty acid supplementation in protecting muscle loss during muscle-disuse and in cancer cachexia, and critically evaluate the molecular mechanisms that underpin the phenotypic changes observed in skeletal muscle with omega-3 fatty acid intake.


Created by admin. Last Modification: Monday November 11, 2019 15:55:16 GMT-0000 by admin. (Version 6)
Omega-3 helps muscles – Aug 2019        
8562 visitors, last modified 11 Nov, 2019,
Printer Friendly Follow this page for updates

Attached files

ID Name Comment Uploaded Size Downloads
12589 Omegs-3 muscle.jpg admin 06 Sep, 2019 74.12 Kb 584
12588 Muscle week.jpg admin 06 Sep, 2019 28.65 Kb 517
12587 Omega-3 muscle.pdf admin 06 Sep, 2019 612.47 Kb 668