- Effects of an 8-week high-dose vitamin D supplementation on fatigue and neuropsychiatric manifestations in post-COVID syndrome: A randomized controlled trial
- VitaminDWiki - 50,000 IU of Vitamin D - many studies
- VitaminDWiki – Additional health problems fought by 50,000 IU weekly
- VitaminDWiki – Long-COVID is now the biggest COVID concern - many studies
Effects of an 8-week high-dose vitamin D supplementation on fatigue and neuropsychiatric manifestations in post-COVID syndrome: A randomized controlled trial
Psychiatry Clin Neurosci. 2024 Jul 28. doi: 10.1111/pcn.13716 PDF is behind a paywall – but references are not behind paywall
Veevarin Charoenporn 1 2 3, Parunkul Tungsukruthai 3, Pitchapa Teacharushatakit 4, Sirashat Hanvivattanakul 4, Kusuma Sriyakul 3, Sophida Sukprasert 3, Chuntida Kamalashiran 3, Sucharat Tungsukruthai 5, Thammanard Charernboon 1 6
Aim: This study evaluated the effectiveness of high-dose vitamin D supplementation in alleviating fatigue and neuropsychiatric symptoms in post-COVID syndrome.
Methods: In an 8-week, double-blind, randomized, placebo-controlled trial, 80 patients with post-COVID fatigue or neuropsychiatric symptoms were enrolled. Participants were randomly assigned to receive either 60,000 IU of vitamin D weekly (n = 40) or a placebo (n = 40) for 8 weeks. Clinical outcomes were assessed using the 11-item Chalder Fatigue Scale (CFQ-11); 21-item Depression, Anxiety, and Stress Scale (DASS-21); Pittsburgh Sleep Quality Index (PSQI); Addenbrooke's Cognitive Examination III (ACE); and Trail Making Test A and B (TMT-A and TMT-B). Baseline and 8-week measurements of inflammatory markers, including interleukin 6 (IL-6) and C-reactive protein (CRP), were also collected.
Results: Significant improvements were found in the vitamin D group for
- CFQ (coefficient -3.5, P = 0.024),
- DASS-anxiety (-2.0, P = 0.011), and
- ACE (2.1, P = 0.012).
No significant differences were observed in PSQI, DASS-depression, TMT, IL-6, or CRP levels. The incidence of adverse events was comparable between groups, with no serious adverse events reported.
Conclusion: High-dose vitamin D supplementation may benefit patients with post-COVID syndrome by reducing fatigue, alleviating anxiety, and improving cognitive symptoms, with minimal side effects.
VitaminDWiki - 50,000 IU of Vitamin D - many studies
VitaminDWiki – Additional health problems fought by 50,000 IU weekly
ADHD, Anxiety, Asthma, Autism, Back Pain, BPH (prostate), Cancer - Breast, Cancer - Colon, Cancer - Prostate, Cardiovascular, Chronic Obstructive Pulmonary Disease, Cognitive Decline, Colds, COVID, Depression, Diabetes, Endometriosis, Falls, Fibromyalgia, Hashimoto's Thyroiditis, Hay Fever, Heart Failure, Hives, Hypertension – Pulmonary, Immune System, Infant, Inflammatory Bowel Syndrome, Influenza, Kidney Disease, Knee-Pain, Lupus, Migraine, Multiple Sclerosis, Muscles - women, Obesity, Pain - Chronic, Pain - Growing, PMS, Preeclampsia, Premature Birth, Respiratory Tract Infection, Schizophrenia, Sleep-Poor, Sleep Apnea, Smoking, Sports Performance, Stroke, Surgery, Tonsilitis, Tuberculosis, Ulcerative Colitis, Ulcers – Venous, Urinary Tract Infection click here for proof
VitaminDWiki – Long-COVID is now the biggest COVID concern - many studies