Vitamin D Intervention Clinical Trials

Intervention = provide vitamin D and see if it prevents or treats a health problem

Most are Random Controlled Clinical Trials

See also VitaminDWiki

• Vitamin D intervention – 1204 clinical trials – May 2014 update

• Overview Evidence for vitamin D

• Proof that Vitamin D Works 24 health problems as of Feb 2013

• Can Observational Studies be as good as Random Controlled Trials for Vitamin D Feb 2013

  • Interventions can be Observational Studies or Random Controlled Trials

• [(Evidence+that+the+minimum+vitamin+D+blood+level+is+30+ng+–+Nov+2012)]

• Overview Vitamin D Intervention

• Hypothesis of Vitamin D and Diseases - and strength of evidence

• All items in category Vitamin D Evidence items

• National Institute of Health - Strength of Vitamin D Evidence

• Evaluating the vitamin D evidence - Dr. Heaney Dec 2010 slide presentation

• Summary of Vitamin D trials - Grant Jan 2012

• Vitamin D also TREATS

Number of Invertention Trials listed in US

Intervene by giving vitamin D to some or all of the participants, then observe any resulting prevention and/or treatment

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Abdominal Neoplasms 1

Abdominal Obesity Metabolic Syndrome 6

Acne Vulgaris 2

Acquired Immunodeficiency Syndrome 25

Acute Chest Syndrome 1

Acute Coronary Syndrome 1

Acute Erythroblastic Leukemia 1

Acute Erythroid Leukemia 1

Acute Lymphoblastic Leukemia 4

Acute Lymphoblastic Leukemia, Childhood 2

Acute Megakaryoblastic Leukemia 1

Acute Monoblastic Leukemia 1

Acute Myeloblastic Leukemia With Maturation 1

Acute Myeloblastic Leukemia Without Maturation 1

Acute Myelocytic Leukemia 1

Acute Myeloid Leukemia, Adult 1

Acute Myelomonocytic Leukemia 1

Acute Non Lymphoblastic Leukemia 1

Adenocarcinoma 12

Adenocarcinoma of the Appendix 2

Adenocarcinoma, Mucinous 12

Adenoma 4

Adenomatous Polyps 4

Adnexal Diseases 5

Albright's Hereditary Osteodystrophy 1

Albuminuria 5

Alcohol-Induced Disorders 1

Alcohol-Related Disorders 1

Allergic Bronchopulmonary Aspergillosis 1

Alopecia 1

Alopecia Areata 1

Alzheimer Disease 3

Alzheimer Disease Familial 3

Amenorrhea 1

Anaplastic Large Cell Lymphoma 1

Anaplastic Plasmacytoma 1

Anemia 23

Anemia, Aplastic 1

Anemia, Hemolytic 4

Anemia, Hemolytic, Congenital 4

Anemia, Hypochromic 6

Anemia, Iron-Deficiency 7

Anemia, Refractory 2

Anemia, Refractory, with Excess of Blasts 2

Anemia, Sickle Cell 3

Angina Pectoris 1

Angioedema 2

Angioimmunoblastic Lymphadenopathy With Dysproteinemia 1

Anorexia 1

Anorexia Nervosa 1

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 1

Aortic Valve Stenosis 2

Aplastic Anemia 1

Apnea 1

Apraxias 1

Arterial Occlusive Diseases 13

Arteriosclerosis 13

Arteriovenous Fistula 1

Arteriovenous Malformations 1

Arteritis 1

Arthralgia 3

Arthritis 12

Arthritis, Juvenile Rheumatoid 1

Arthritis, Rheumatoid 8

Ascorbic Acid Deficiency 1

Aspergillosis 1

Aspergillosis, Allergic Bronchopulmonary 1

Asthenia 3

Asthma 21

Astrocytoma 1

Atherosclerosis 6

Atrophy 7

Autistic Disorder 2

Autoimmune Diseases 46

Autoimmune Diseases of the Nervous System 17

Avitaminosis 243

B-cell Lymphomas 1

Back Injuries 2

Back Pain 1

Bacterial Infections 19

Barrett Esophagus 1

Basal Ganglia Diseases 3

Behavioral Symptoms 5

Berger Disease 2

Beta-Thalassemia 1

Birth Weight 8

Blood Coagulation Disorders 5

Blood Coagulation Disorders, Inherited 1

Blood Protein Disorders 3

Body Weight 59

Body Weight Changes 2

Bone Cancer 1

Bone Demineralization, Pathologic 1

Bone Diseases 147

Bone Diseases, Developmental 1

Bone Diseases, Endocrine 1

Bone Diseases, Metabolic 134

Bone Marrow Diseases 8

Bone Neoplasms 1

Bone Resorption 4

Brain Diseases 14

Brain Diseases, Metabolic 1

Brain Diseases, Metabolic, Inborn 1

Breast Cancer, Male 1

Breast Diseases 31

Breast Neoplasms 32

Breast Neoplasms, Male 1

Bronchial Diseases 22

Bronchial Neoplasms 2

Bronchiolitis 1

Bronchiolitis Obliterans 1

Bronchitis 1

Bronchopulmonary Dysplasia 2

Burns 3

Calcinosis 15

Calcium Metabolism Disorders 58

Calculi 3

Camurati-Engelmann Disease 1

Carcinoma 11

Carcinoma in Situ 1

Carcinoma, Basal Cell 1

Carcinoma, Bronchogenic 2

Carcinoma, Ductal, Breast 1

Carcinoma, Hepatocellular 1

Carcinoma, Intraductal, Noninfiltrating 1

Carcinoma, Lobular 1

Carcinoma, Non-Small-Cell Lung 3

Cardiomegaly 7

Cardiomyopathies 2

Cardiovascular Abnormalities 1

Central Nervous System Diseases 16

Cerebral Infarction 1

Cerebrovascular Disorders 2

Charcot-Marie-Tooth Disease 1

Chest Pain 1

Chickenpox 1

Child Development Disorders, Pervasive 2

Child Nutrition Disorders 1

Cholangiocarcinoma 1

Chromosome Aberrations 1

Chromosome Disorders 1

Chronic Disease 3

Chronic Lymphocytic Leukemia 2

Chronic Myeloid Leukemia 2

Chronic Myelomonocytic Leukemia 4

Chronic Myeloproliferative Disorders 4

Coagulation Protein Disorders 1

Cognition Disorders 7

Colitis 3

Colitis, Ulcerative 3

Collagen Diseases 1

Colonic Diseases 16

Colonic Diseases, Functional 1

Colonic Neoplasms 7

Colonic Polyps 4

Colorectal Neoplasms 13

Common Cold 3

Congenital Abnormalities 7

Conjunctival Diseases 2

Conjunctivitis 2

Conjunctivitis, Allergic 1

Connective Tissue Diseases 18

Constriction, Pathologic 2

Corneal Diseases 1

Coronary Artery Disease 10

Coronary Disease 9

Critical Illness 2

Crohn Disease 12

Cross Infection 1

Cutaneous Lupus Erythematosus 1

Cutaneous T-cell Lymphoma 1

Cystadenocarcinoma 2

Cystic Fibrosis 7

Cysts 3

Death 3

Death, Sudden 1

Death, Sudden, Cardiac 1

Deficiency Diseases 246

Deglutition Disorders 1

Delirium 7

Delirium, Dementia, Amnestic, Cognitive Disorders 7

Dementia 7

Demyelinating Autoimmune Diseases, CNS 16

Demyelinating Diseases 17

Depression 6

Depressive Disorder 6

Dermatitis 8

Dermatitis, Allergic Contact 1

Dermatitis, Atopic 4

Dermatitis, Contact 3

Developmental Disabilities 2

Di Guglielmo's Syndrome 1

Diabetes Complications 9

Diabetes Mellitus 83

Diabetes Mellitus, Type 1 12

Diabetes Mellitus, Type 2 43

Diabetic Angiopathies 1

Diabetic Nephropathies 8

Diabetic Retinopathy 1

Diarrhea 2

Diffuse Scleroderma 1

Digestive System Abnormalities 1

Digestive System Diseases 56

Digestive System Neoplasms 18

Dilatation, Pathologic 3

Disease Progression 7

Disease Susceptibility 1

DNA Virus Infections 2

Dry Eye Syndromes 1

Dyslipidemias 6

Dyssomnias 1

Eating Disorders 1

Eccentrochondrodysplasia 1

Eclampsia 2

Eczema 3

Edema 1

Embolism 1

Embolism and Thrombosis 1

Emergencies 1

Endocrine Gland Neoplasms 5

Endocrine System Diseases 156

Endometriosis 1

Enterovirus Infections 9

Epilepsy 1

Esophageal Diseases 2

Exanthema 4

Eye Diseases 6

Facial Dermatoses 2

Facies 2

Fallopian Tube Cancer 1

Fallopian Tube Neoplasms 1

Fatigue 3

Fatty Liver 4

Fatty Liver, Alcoholic 1

Fecal Incontinence 1

Femoral Fractures 4

Femur Head Necrosis 1

Fetal Diseases 3

Fetal Growth Retardation 3

Fever 1

Fibrosis 7

Fistula 1

Flushing 1

Follicular Lymphoma 1

Food Hypersensitivity 1

Fractures, Bone 36

Fractures, Stress 1

Fractures, Ununited 1

---

Gait Apraxia 1

Gait Disorders, Neurologic 1

Galactorrhoea-Hyperprolactinaemia 1

Ganglion Cysts 3

Gastroenteritis 15

Gastrointestinal Diseases 56

Gastrointestinal Neoplasms 18

Gaucher Disease 1

Gaucher Disease Type 1 1

Genetic Diseases, Inborn 22

Genetic Diseases, X-Linked 3

Genetic Predisposition to Disease 1

Genital Diseases, Female 9

Genital Diseases, Male 25

Genital Neoplasms, Female 2

Genital Neoplasms, Male 22

Giant Cell Arteritis 1

Gingival Diseases 2

Gingivitis 1

Glioblastoma 1

Glioma 1

Glomerulonephritis 3

Glomerulonephritis, IGA 2

Glucose Intolerance 12

Glucose Metabolism Disorders 92

Gonadal Disorders 7

Gram-Positive Bacterial Infections 16

Growth Disorders 3

Head and Neck Neoplasms 4

Headache 3

Headache Disorders 2

Headache Disorders, Primary 2

Heart Arrest 1

Heart Diseases 35

Heart Failure 16

Heart Valve Diseases 2

Helminthiasis 1

Hematologic Diseases 32

Hematologic Neoplasms 1

Hemoglobinopathies 4

Hemolysis 4

Hemophilia 1

Hemophilia A 1

Hemophilia A, Congenital 1

Hemophilia B 1

Hemorrhagic Disorders 5

Hemostatic Disorders 5

Hepadnaviridae Infections 1

Hepatitis 9

Hepatitis A 9

Hepatitis B 1

Hepatitis B, Chronic 1

Hepatitis C 8

Hepatitis C, Chronic 7

Hepatitis, Chronic 8

Hepatitis, Viral, Human 9

Hereditary Neuropathy With Liability to Pressure Palsy 1

Hereditary Sensory and Motor Neuropathy 1

Herpes Zoster 1

Herpesviridae Infections 1

Hip Fractures 4

Hip Injuries 4

HIV Infections 25

HIV Seropositivity 2

Hot Flashes 1

Hypercalcemia 13

Hypercalciuria 4

Hypercholesterolemia 2

Hyperemia 1

Hyperglycemia 12

Hyperinsulinism 36

Hyperkinesis 1

Hyperlipidemias 5

Hyperparathyroidism 81

Hyperparathyroidism, Primary 8

Hyperparathyroidism, Secondary 64

Hyperphosphatemia 2

Hyperplasia 2

Hyperprolactinemia 1

Hypersensitivity 34

Hypersensitivity, Delayed 1

Hypersensitivity, Immediate 30

Hypertension 22

Hypertension, Pregnancy-Induced 2

Hyperthyroidism 2

Hypertriglyceridemia 2

Hypertrophy 9

Hypertrophy, Left Ventricular 7

Hypocalcemia 9

Hypogonadism 2

Hypoparathyroidism 5

Hypophosphatemia 3

Hypophosphatemia, Familial 2

Hypophosphatemic Rickets 2

Hypophosphatemic Rickets, X-Linked Dominant 2

Hypotrichosis 1

Idiopathic Adolescent Scoliosis 1

Idiopathic Myopathy 1

Immunoblastic Lymphadenopathy 1

Immunologic Deficiency Syndromes 19

Immunoproliferative Disorders 12

Infant Nutrition Disorders 1

Infant, Newborn, Diseases 10

Infant, Premature, Diseases 2

Infarction 1

Infertility 4

Infertility, Male 1

Inflammation 38

Inflammatory Bowel Diseases 15

Influenza, Human 6

Insulin Resistance 48

Intestinal Diseases 31

Intestinal Neoplasms 13

Intestinal Polyps 2

Intrahepatic Cholangiocarcinoma 1

Iron Metabolism Disorders 6

Irritable Bowel Syndrome 1

Ischemia 12

Joint Diseases 14

Juvenile Osteoporosis 1

Keratitis 1

Keratoconjunctivitis 1

Keratoconjunctivitis Sicca 1

Kidney Calculi 2

Kidney Diseases 127

Kidney Failure, Chronic 100

Lacerations 1

Lacrimal Apparatus Diseases 1

Latent Tuberculosis 1

Leg Injuries 4

Lentivirus Infections 18

Leukemia 12

Leukemia, B-Cell 2

Leukemia, B-cell, Chronic 2

Leukemia, Erythroblastic, Acute 1

Leukemia, Lymphocytic, Chronic, B-Cell 2

Leukemia, Lymphoid 6

Leukemia, Megakaryoblastic, Acute 1

Leukemia, Monocytic, Acute 1

Leukemia, Myelogenous, Chronic, BCR-ABL Positive 2

Leukemia, Myeloid 3

Leukemia, Myeloid, Acute 1

Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative 2

Leukemia, Myelomonocytic, Acute 2

Leukemia, Myelomonocytic, Chronic 4

Lipid Metabolism Disorders 6

Lipid Metabolism, Inborn Errors 1

Lipidoses 1

Liver Cancer 2

Liver Diseases 15

Liver Diseases, Alcoholic 1

Liver Neoplasms 2

Localized Scleroderma 1

Lung Diseases 53

Lung Diseases, Fungal 1

Lung Diseases, Interstitial 1

Lung Diseases, Obstructive 28

Lung Injury 2

Lung Neoplasms 4

Lupus Erythematosus, Cutaneous 1

Lupus Erythematosus, Systemic 7

Lupus Nephritis 1

Lymphatic Diseases 9

Lymphoblastic Lymphoma 1

Lymphoma 8

Lymphoma, B-Cell 1

Lymphoma, Extranodal NK-T-Cell 1

Lymphoma, Follicular 1

Lymphoma, Large B-Cell, Diffuse 1

Lymphoma, Large-cell 1

Lymphoma, Large-Cell, Anaplastic 1

Lymphoma, Non-Hodgkin 3

Lymphoma, Small Cleaved-cell, Diffuse 2

Lymphoma, T-Cell 1

Lymphoma, T-Cell, Cutaneous 1

Lymphoma, T-Cell, Peripheral 1

Lymphoproliferative Disorders 12

Lysosomal Storage Diseases 1

Lysosomal Storage Diseases, Nervous System 1

Macular Degeneration 1

Magnesium Deficiency 1

Malabsorption Syndromes 2

Malaria 4

Malnutrition 254

Melanoma 5

Melanoma, Familial 2

Menopause 10

Menopause, Premature 1

Menstruation Disturbances 2

Mental Disorders 18

Mental Disorders Diagnosed in Childhood 2

Mental Retardation 1

Metabolic Diseases 159

Metabolic Syndrome X 8

Metabolism, Inborn Errors 4

Metal Metabolism, Inborn Errors 3

Migraine Disorders 2

Mood Disorders 4

Mouth Diseases 4

Mouth Neoplasms 1

Movement Disorders 3

Mucopolysaccharidosis IV 1

Multiple Myeloma 3

Multiple Sclerosis 16

Multiple Sclerosis, Relapsing-Remitting 5

Muscle Cramp 1

Muscle Weakness 2

Muscular Atrophy 7

Muscular Diseases 4

Musculoskeletal Diseases 160

Mycobacterium Infections 16

Mycoses 1

Myelodysplastic Syndromes 6

Myelodysplastic-Myeloproliferative Diseases 4

Myelodysplastic/myeloproliferative Disease 4

Myeloproliferative Disorders 4

Myocardial Ischemia 10

Myositis 1

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Nasal Polyps 1

Nasopharyngeal Carcinoma 1

Nasopharyngeal Neoplasms 1

Necrosis 6

Neoplasm Metastasis 78

Neoplasm, Residual 1

Neoplasms, Basal Cell 1

Neoplasms, Cystic, Mucinous, and Serous 4

Neoplasms, Germ Cell and Embryonal 6

Neoplasms, Glandular and Epithelial 11

Neoplasms, Nerve Tissue 6

Neoplasms, Neuroepithelial 1

Neoplasms, Plasma Cell 3

Neoplasms, Second Primary 3

Neoplastic Processes 5

Nephritis 3

Nephrolithiasis 3

Nerve Compression Syndromes 1

Neuritis 1

Neurobehavioral Manifestations 2

Neurodegenerative Diseases 6

Neuroectodermal Tumors 6

Neuroendocrine Tumors 5

Neuroepithelioma 6

Neurologic Manifestations 15

Neuromuscular Diseases 4

Neurotoxicity Syndromes 2

Nevus 5

Nevus, Pigmented 5

Nonalcoholic Steatohepatitis 4

Nutrition Disorders 285

Obesity 55

Obesity, Morbid 2

Obstetric Labor Complications 2

Obstetric Labor, Premature 2

Optic Nerve Diseases 1

Optic Neuritis 1

Oral Cancer 1

Orthomyxoviridae Infections 3

Osteitis 3

Osteitis Deformans 3

Osteoarthritis 5

Osteoarthritis, Knee 4

Osteochondrodysplasias 1

Osteogenesis Imperfecta 1

Osteomalacia 4

Osteonecrosis 1

Osteoporosis 103

Osteoporosis, Postmenopausal 18

Osteoporotic Fractures 2

Otorhinolaryngologic Diseases 7

Otorhinolaryngologic Neoplasms 1

Ovarian Cancer 2

Ovarian Cysts 3

Ovarian Diseases 5

Ovarian Neoplasms 2

Overnutrition 47

Overweight 50

Pain 17

Pancreatic Cancer 1

Pancreatic Diseases 10

Pancreatic Neoplasms 1

Pancreatitis 2

Pancreatitis, Chronic 2

Pancytopenia 1

Paraproteinemias 3

Parasitic Diseases 2

Parasomnias 2

Parathyroid Diseases 79

Parathyroid Neoplasms 1

Paresis 2

Parkinson Disease 3

Parkinsonian Disorders 3

Pathological Conditions, Anatomical 26

Pediatric Crohns Disease 1

Penile Induration 1

Periodontal Diseases 3

Periodontitis 1

Peripheral Arterial Disease 1

Peripheral Nervous System Diseases 3

Peripheral T-cell Lymphoma 1

Peripheral Vascular Diseases 1

Peritoneal Diseases 1

Peritoneal Neoplasms 1

Peyronie Disease 1

Pharyngeal Diseases 3

Pharyngeal Neoplasms 1

Pharyngitis 1

Phosphorus Metabolism Disorders 4

Picornaviridae Infections 12

Pituitary Diseases 1

Pityriasis 1

Pityriasis Rosea 1

Plasmacytoma 1

Pneumonia 4

Pneumonia, Bacterial 1

Poisoning 2

Polycystic Ovary Syndrome 3

Polymyalgia Rheumatica 1

Polymyositis 1

Polyneuropathies 1

Polyps 6

Postoperative Complications 1

Pre-Eclampsia 2

Precancerous Conditions 6

Precursor Cell Lymphoblastic Leukemia-Lymphoma 4

Prediabetic State 10

Pregnancy Complications 8

Prehypertension 2

Preleukemia 6

Premature Birth 1

Premenstrual Syndrome 1

Primary Ovarian Insufficiency 1

Prostatic Diseases 22

Prostatic Neoplasms 22

Proteinuria 10

Protozoan Infections 2

Pruritus 2

Pseudohypoparathyroidism 1

Pseudopseudohypoparathyroidism 1

Psoriasis 10

Psychomotor Disorders 1

Psychotic Disorders 18

Pulmonary Aspergillosis 1

Pulmonary Disease, Chronic Obstructive 8

Pure Red Cell Aplasia 1

Quality of Life 15

Rectal Diseases 12

Rectal Neoplasms 4

Recurrence 4

Red-Cell Aplasia, Pure 1

Renal Insufficiency 105

Renal Insufficiency, Chronic 105

Renal Osteodystrophy 5

Renal Tubular Transport, Inborn Errors 2

Respiration Disorders 9

Respiratory Hypersensitivity 23

Respiratory Insufficiency 1

Respiratory Sounds 1

Respiratory Tract Diseases 68

Respiratory Tract Infections 31

Respiratory Tract Neoplasms 4

Retinal Degeneration 1

Retinal Diseases 3

Retinal Vein Occlusion 1

Retroviridae Infections 18

Rheumatic Diseases 12

Rhinitis 2

Rhinitis, Allergic, Seasonal 1

Rickets 39

RNA Virus Infections 33

Roussy Levy Syndrome 1

Rupture 1

Sarcopenia 8

Schizophrenia 3

Schizophrenia and Disorders with Psychotic Features 3

Scleroderma, Diffuse 1

Scleroderma, Localized 1

Scleroderma, Systemic 1

Sclerosis 16

Scoliosis 1

Scurvy 1

Seasonal Affective Disorder 1

Sebaceous Gland Diseases 2

Seizures 1

Sepsis 2

Sexually Transmitted Diseases 18

Sexually Transmitted Diseases, Viral 18

Shock 2

Short Bowel Syndrome 1

Sickle Cell Anemia 3

Sideroblastic Anemia Pyridoxine-refractory Autosomal Recessive 2

Signs and Symptoms, Digestive 2

Signs and Symptoms, Respiratory 2

Sinusitis 2

Skin Diseases 60

Skin Diseases, Eczematous 8

Skin Diseases, Genetic 4

Skin Diseases, Papulosquamous 10

Skin Diseases, Vascular 3

Skin Manifestations 1

Skin Neoplasms 3

Sleep Apnea Syndromes 1

Sleep Apnea, Obstructive 1

Sleep Disorders 2

Sleep Disorders, Intrinsic 1

Sleep-Wake Transition Disorders 1

Small Cell Lung Carcinoma 1

Spastic Paraplegia Epilepsy Mental Retardation 1

Sphingolipidoses 1

Spinal Cord Diseases 2

Spinal Cord Injuries 2

Spinal Curvatures 1

Spinal Diseases 1

Spinal Fractures 4

Spinal Injuries 2

Stomatognathic Diseases 6

Stress, Psychological 1

Stroke 1

Substance-Related Disorders 3

Syndrome 53

Synovial Cyst 3

Systemic Inflammatory Response Syndrome 2

Systemic Scleroderma 1

Systemic Vasculitis 1

Tauopathies 3

Testicular Diseases 1

Thalassemia 1

Thoracic Neoplasms 4

Thrombosis 1

Thyroid Diseases 3

Thyroid Neoplasms 2

Thyroid Nodule 1

Tissue Adhesions 1

Tonsillitis 1

Toxemia 2

Trauma, Nervous System 2

Tuberculosis 16

Tuberculosis, Pulmonary 8

Ulcer 3

Urinary Calculi 2

Urinary Incontinence 1

Urinary Retention 2

Urination Disorders 9

Urogenital Neoplasms 24

Urolithiasis 4

Urologic Diseases 130

Urological Manifestations 10

Urticaria 2

Vaginal Diseases 1

Vaginitis 1

Vaginosis, Bacterial 1

Vascular Diseases 42

Vascular Malformations 1

Vasculitis 1

Venous Thromboembolism 1

Venous Thrombosis 1

Ventilator-Induced Lung Injury 2

Virus Diseases 35

Visceral Steatosis 2

Vitamin D Deficiency 249

Water-Electrolyte Imbalance 18

Wegener Granulomatosis 1

Weight Loss 8

Williams Syndrome 1

Wounds and Injuries 24

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Intervention Trials listed at WHO

Newly listed at WHO for approximately previous 11 months ending Feb 2013

Vitamin D Levels in Patients With Central Retinal Vein Occlusion- a Prospective Controlled Study

Effect of low caloric diet with and without vitamin D supplementation in non alcoholic fatty liver

DIABGAD - Trial to Preserve Insulin Secretion in Type 1 Diabetes Using GAD-Alum (Diamyd) in Combination With Vitamin D and Ibuprofen

Vitamin D and Cardiac Autonomic Tone in Hemodialysis

Development of Non-invasive Method for Quantifying Vitamin D Levels in the Body Using Spectroscopy

Vitamin D supplements to prevent depression and poor physical function in persons over 60 years

The Effect of Inactive and Active Vitamin D on Serum Sclerostin/dickkopf1 Levels

Assessing the Effects of Alfacalcidol Intake on Expression of Involed Gene in Metabolism in Obese Subjects

EFFECT OF VITAMIN D3 SUPPLEMENTATION ON INSULIN SENSITIVITY IN PREDIABETES.

Vitamin D and Mammographic Breast Density

Vitamin D Treatment and Hypogonadism in Men

DO-HEALTH / Vitamin D3 - Omega3 - Home Exercise - Healthy Ageing and Longevity Trial

Effect of vitamin D supplementation on primary hypertension: a randomized clinical trial

Vitamin D Supplementation in Patients With Diabetes Mellitus Type 2

The Genetics Behind Vitamin D Status (VitDgen)

Vitamin D for Women at Increased Risk of Developing Ovarian, Fallopian, or Primary Peritoneal Cancer

Comparison of the efficacy of two regimens of Vitamin D supplementation in preventing vitamin D deficiency among preterm infants.

Effect of Vitamin D Supplementation on Endothelial Function in Obese Adolescents

A clinical trial to evaluate combination of 4 cardiovascular drugs and aspirin and Vitamin D supplementation in subjects for cardiovascular diseases

Efficacy of oral Vitamin D therapy in children with Vitamin D deficiency

The effect of vitamin D supplementation in Non Alcoholic Fatty Liver Disease treatment

Duration of Vitamin D Stores After Prolonged Vitamin D Substitution

?Vitamin D as add-on treatment for relapsing-remitting multiple sclerosis: an unicentric, randomized, double-blinded, placebo-controlled clinical trial?

Effect of Vitamin D Supplementation on Glucose Tolerance in Subjects at Risk for Diabetes With Low Vitamin D.

Dose-related Effects of Vitamin D3 on Immune Responses in Patients With Clinically Isolated Syndrome

Gestational diabetes and vitamin D

Effect of High-Dose Vitamin D on Bone Density in Osteogenesis Imperfecta

Vitamin D3 in Pediatric SLE

a study to evaluate the role of vitamin-D supllementation in teatment of patints with type 2 diabetes

The effect of vitamin D on breast density in women older than 40 years

Postoperative treatment with Vitamin D for patients with a history of Bariatric Surgery in C and U County.

The effect of vitamin D supplementation on blood pressure in hypertensive patients with vitamin D deficiency

A Randomized, Parallel, Double-blind, Placebo-controlled Study of Vitamin D as Prophylactic Treatment for Migraine

Immune Reconstitution in Tuberculosis Disease

Immune Reconstitution in HIV Disease (IREHIV)

Clinical Trial to Determine the Efficacy of Vitamin D for Acne Therapy

The Effect of Hypovitaminosis D and Vitamin D Supplementation on Fracture Nonunion Rates

Bioavailability of Vitamin D in Children and Adolescents With Crohn's Disease

The Effect of Oral Vitamin D Versus Narrow-Band UV-B Exposure on the Lipid Profile

DRISK Study

A Study of Vitamin D supplementation in breastfeeding young children

High Dose Preoperative Cholecalciferol Supplementation and Perioperative Vitamin D Status

Serum Vitamin D Levels and Peripheral Neuropathy Among Multiple Myeloma Patients

Effect of Vitamin D Supplementation on Coronary Calcification and Parathyroid Hormone in CKD Patients

Vitamin D In Older People

Pharmacokinetics of Vitamin D in Multiple Sclerosis and in Health

Immunological response of vitamin D

The effect of vitamin D on epilepsy

Vitamin D supplementation to reduce CardioVascular risk factors

Vitamin D as an add-on Therapy With Pegylated Interferon and Ribavirin for Chronic Hepatitis c

Effects of Vitamin D and Calcium Supplementation on Inflammatory Biomarkers and Adypocytokines in Diabetic Patients

A Phase 2A Dose-ranging and Pharmacokinetic Study of an Oral Vitamin D Compound (DP001) in Secondary Hyperparathyroidism

Pilot Trial to preserve residual insulin secretion in children and adolescents with recent onset Type 1 diabetes by using GAD-antigen (Diamyd) therapy in combination with Vitamin D and Ibuprofen .

Safety and Efficacy of CTAP101 Capsules to Treat Secondary Hyperparathyroidism in Stage 3 or 4 CKD and Vitamin D Insufficiency

Swiss Study on Vitamin D and Calcium in Nursing Homes

Vitamin D and Preeclampsia

Vitamin D, Cardiovascular Disease, and African Americans

Vitamin D, Steroids, and Asthma in African American Youth

vitamin D and calcium Supplementation reduces the complication of letrozole in breast cancer patients

25-Hydroxyvitamin D Levels and the Risk of Stroke

The International Polycap Study 3 (TIPS-3)

Optimising Vitamin D Status in Older People (VDOP)

Multicenter, randomized, double-blind, placebo controlled, parallel group trial to evaluate the effect of Vitamin D supplementation for fall prevention

Vitamin D3 Supplementation for Heart Failure Patients

Bone Health and Vitamin D Status

The VALDIATE-D Study

Vitamin D Loading Dose in Advanced Lung Cancer

Vitamin D Deficiency and Postoperative Hypocalcemia

Maternal Vitamin D Status and Neonatal Bone Strength

Sunlight Exposure and Vitamin D Status of Children of South Asian Ethnicity Living in the UK

Wheezing in Black Preterm Infants: Impact of Vitamin D Supplementation Strategy

Vitamin D Supplementation for Extremely Preterm Infants

Effect of Omega-3 Fatty Acid on Vitamin D Activation

To study the effects of CollagenCal? in the management of Osteoporosis in women.

Hepatitis immunisation and vitamin D supplementation

Vitamin D supplementation in the obese

Vitamin D Supplementation in Polymorphic Light Eruption

To study levels of calcium, phosphorous and vitamin in body fluids before and after a 12 weeks course of pioglitazone, an anti diabetic agent, in pateints with diabetes

Clinical Trial of Phenylbutyrate and Vitamin D in Tuberculosis (TB)

The effect of vitamin D on the glycemic control and non-alcoholic fatty liver disease

Testosterone Pellets Plus Vitamin D and E Versus Vitamin D and E Alone for the Treatment of Peyronie's Disease

Biochemical Efficacy and Safety Trial of vitamin D (BEST-D)

The Effect of Vitamin D Repletion in Patients With Hepatocellular Carcinoma on the Orthotopic Liver Transplant List

Vitamin D Supplementation in Overweight/Obese African American Adults and Youth (D-SUNNY)

Vitamin D During Pregnancy

Is Treatment of Vitamin D Deficiency Associated With Resolution of Statin-Induced Muscular Symptoms

The effect of Friso Premature on growth, sleep characteristics, Nutritional status parameters and inflammatory markers.

Cholecalciferol and Flu Vaccine in Treating Healthy Participants

Effect of Vitamin D supplementation in HIV-infected children, adolescents and young adults with hypovitaminosis D.

Optimizing Vitamin D in the Elderly

Randomized double-blind intervention trial to assess the efficacy of vitamin D3 supplementation vs placebo in reducing hepatic steato-inflammation and cardio-metabolic

   risk profile in patients affected by type 2 diabetes and non-alcoholic fatty liver disease (NAFLD/NASH)

Vitamin D supplementation in polymorphic light eruption: Randomized double-blinded placebo-controlled trial - Vitamin D and PLE

Study to evaluate the pharmacokinetic of vitamin D in patients with obesity after bariatric surgery

The efficacy and safety analysis of Peg-IFN/RBV/Vitamin D3 therapy for liver cirrhosis with hepatitis c persistent infection: RCT Study

Effect of Bazedoxifene to osteoporotic patients under active vitamin D treatment

Metabolic Syndrome and Insulin Resistance at Allina

Efficacy of Different Regimens of Vitamin D Supplementation in Preterm Infants- A Randomized Double Blind Trial

Phase III Clinical Trial of DP-R206 and Bonvia In Postmenopausal Women With Osteoporosis

Impact of Vitamin D Supplementation on Cardiometabolic Risk Factors [The Daily D Health Study]

Open Label Clinical Trial of Vitamin D in Children With Autism

UK etc

22 Clinical Trials as of Feb 2013

EU

222 Clinical Trails as of Feb 2013

India

no vitamin D trials listed Feb 2013

Australia/NZ

no vitamin D trials listed Feb 2013

Japan etc

52 for Vitamin D (do not use quotes = "Vitamin D")

Has options to search elsewhere in the world, but they do not appear to work

Germany

7 vitamin D intervention trials listed Feb 2013