Respiratory infections reduced by 63 percent with 4000 IU vitamin D daily - RCT

Highlights of Report in Swedish translated by Google

• Peter Bergman and his colleagues are fortunate to have 140 patients in daily treatment for one year with either vitamin D (4000 IU) or a placebo.

• The study was double-blind: neither the patients - all of which were susceptible to infections - nor caregivers knew who belonged to which group before the trial was over.

• The results show that vitamin D reduced patient discomfort.

• The probability of requiring treatment with antibiotics during the study period was63 % lower in the vitamin D group compared with the placebo group, and the incidence of fungal infections, including respiratory, decreased.

  Chart from 2015 publication

Note: if takes ~100 days for the vitamin D levels to plateau (thus, no benefit is expected until then)

Respiratory tract infection eliminated in 36 percent of people

Types of Respiratory Infections

Vitamin D did particularly well with

• Moraxella catharralis

• Staphylococcus aureus

• Pseudomona aeruginosa

• Fungal infection

Adverse effects: fewer with vitamin D than with placebo

Suspect that Vitamin D caused the reduction in:

• Gastrointestinal

• Cardiovascular

• Infections

The RTI aspects

📄 Download the English 2012 PDF from VitaminDWiki

📄 Download the English 2015 PDF from VitaminDWiki

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See also VitaminDWiki

• VitaminDWiki RTI studies26 as of Sept 2021

• 4,000 IU of Vitamin D - many pages

• Respiratory Tract Infection risk reduced 2X by Vitamin D loading doses – meta-analysis Jan 2021

• Lower Respiratory Tract Infection in Infants reduced 5.9 X by daily 600 IU of vitamin D (China) - March 2020

• Respiratory tract infections in childhood – vitamin D is needed, no consensus of how much – Oct 2015

• Vitamin D and Respiratory Tract Infections – meta-analysis with charts June 2013

• Vitamin D response time is 3-6 months, not much benefit in first 4 months – RCT July 2017

• Vitamin D in respiratory diseases – Spring 2017

• Respiratory Tract Infection visits 2.5 less likely with vitamin D: Pregnancy 2000 IU, Infant 800 IU – RCT Oct 2014

• All items in Breathing and Vitamin D items

• Hypothesis: Respiratory problems will decrease with increased vitamin D – Jan 2012

• Respiratory Virus risk reduced 35 percent by Vitamin D (14,000 IU weekly) – RCT Oct 2018

• Respiratory diseases helped by vitamin D if initially have low level – RCT review Jan 2015

• Common cold incidence reduced by two thirds (500 IU for IBD with low vitamin D) – RCT Jan 2019

• Vitamin D does not reduce Infectious Disease when not enough is given – March 2015

• Inflammatory diseases: review of vitamin D, with many tables – May 2014 which has the following summary table

See also web

• Prevention of New Respiratory Episodes in Children with Recurrent Respiratory Infections: An Expert Consensus Statement - Nov 2020

  • 1,000 IU of vitamin D was not enough for recurrent RTI

  • 📄 Download the PDF from VitaminDWiki

• Human Metapneumovirus Infection in Hospitalised Children with Acute Lower Respiratory Tract Infection in Hangzhou, China 2013

  • Has a chart showing a very strong relationship with season of low Vitamin D at 30 degrees North latitude in China
  • 
  • Note RTI in Middle East peaks in the summer, not winter, because they stay away from the hot hot sun.