Do not test UK pregnancies for low vitamin D (since 800 IU does not help)

Should routine screening for vitamin D deficiency be performed in pregnancy?

Evidence-Based Practice Evidence-Based Practice Vol. 19 | No. 11 | November 2016

Abstract Should routine screening for vitamin D deficiency be performed in pregnancy?

Evidence-based answer: No. Low vitamin D levels in pregnancy are associated with worse outcomes than no vitamin deficiency; however, supplementation does not conclusively improve outcomes (SOR: B, meta-analyses of observational studies and RCTs). The Royal College of Obstetricians and Gynaecologists (RCOG) recommends against screening for vitamin D deficiency in pregnancy (SOR: C, expert opinion)

The 2014 meta-analysis which they based their decision on generally used 800 IU of vitamin D 137 health problems associated with low vitamin D – meta-meta-analysis April 2014 Over 400 studies of Vitamin D during pregnancy have only rarely found a benefit at 800 IU. Good benefits start at 4,000 IU – 5 times large dose than what the meta-analysis considered If this had been aspirin instead of vitamin D the conclusion could have been: Do not bother testing for headaches if you are only going to prescribe 1/5 of a tablet of aspirin, such a low dose does not help headaches See also VitaminDWiki * 3,800 IU Vitamin D during pregnancy did not help much – RCT Jan 2017 * Gestational Diabetes treated with 50,000 IU every two weeks – RCT Sept 2016 * Preeclampsia reduced by Vitamin D (50,000 IU bi-weekly) and Calcium – Oct 2015 * Preterm birth rate reduced by 43 percent with adequate Vitamin D supplementation – meta-analysis Feb 2017 1. Healthy pregnancies need lots of vitamin D has the following summary {include} 1. Pregnancy category starts with {include} 1. Meta-analyses of Pregnancy and Vitamin D {category}

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Tags: Pregnancy