Depression twice as common in Diabetics (both have low vitamin D)

Created September 2018

Understanding depression in type 2 diabetes: a biological approach in observational studies

F1000Research 2018, 7(F1000 Faculty Rev):1283 Last updated: 15 AUG 2018 [version 1; referees: 2 approved]

Thomas van Sloten1-3, Miranda Schram

Strangely the word vitamin does not occur even once in the PDF * Depression 2X more common among diabetics, both associated with low vitamin D – 2014 * Vitamin D treatment of diabetes (50,000 IU every 2 weeks) augmented by probiotic – RCT June 2018 beck depression inventory (-2.8  vs. -0.9, P = 0.01), * 50,000 IU Vitamin D weekly Improves Mood, Lowers Blood Pressure in Type 2 Diabetics – Oct 2013 * Hypothesis: Vitamin D is the link between Osteoporosis, Obesity, and Diabetes – April 2014 * Low vitamin D is associated with most types of depression: Seasonal Affective Disorder. manic depression, bipolar disorder, dysthymia, pregnancy, Seniors, Suicide Items in both categories Diabetes and Depression are listed here: {category}

📄 Download the PDF from VitaminDWiki

Depression is twice as common in type 2 diabetes as in the general population and is associated with adverse health outcomes. Growing evidence suggest that type 2 diabetes and depression share biological mechanisms. This brief commentary discusses current understanding of shared biological pathways, focussing on hyperglycaemia, (micro)vascular dysfunction, and low-grade inflammation. Although there is accumulating evidence that these pathways are involved in the link between type 2 diabetes and depression, direct evidence of their temporal associations is lacking because of a paucity of longitudinal studies that focus on the pathobiology of both type 2 diabetes and depression.

Tags: Depression Diabetes