ADHD reduced by just 3,000 IU of Vitamin D and methylphenidate for just 12 weeks – RCT

Created February 2018

The Impact of Vitamin D Supplementation on Attention-Deficit Hyperactivity Disorder in Children

Annals of Pharmacotherapy https://doi.org/10.1177/1060028018759471

Hatem Hamed Elshorbagy, MD shorbagy732000@yahoo.com, Naglaa Fathy Barseem, MD, Waleed Elsayed Abdelghani, MD, ...

| | | | | | --- | --- | --- | --- | | Test | Before | After | P Value (smaller is more likely) | | Categories completion | 3.5 | 4.8 | .085 | | Conceptual level | 49 | 83 | .086 | | Inattention | 66 | 55 | .037 | | Hyperactivity | 80 | 57 | .001 | | Impulsivity | 79 | 57 | .001 | | Oppositional | 63 | 52 | .025 | --- 1. VitaminDWiki ADHD and Vitamin D Deficiency category listing has items along with related searches * ADHD 2 times more likely if poor Omega-6 to Omega-3 ratio – meta-analysis May 2016 * Deficiencies of Vitamin D, Iron, Magnesium, and Zinc all associated with ADHD – Sept 2014 Can imagine far better ADHD reduction if 1. Supplementation lasts for > 12 weeks *     some children take 25 weeks to get the full benefit of Vitamin D 1. include some of the following: Omega-3, Magnesium, Zinc, Iron 1. The dose size varies with weight, nutrient deficiency 1. Those children with gut problems are given gut-friendly Vitamin D Perhaps in the future we can prevent ADHD with proper nutrition for mother and/or child --- 1. Wikipedia Methylphenidate = Ritalin -"in 2013 global methylphenidate consumption increased to 2.4 billion doses, a 66% increase from the year before" ADHD

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Background: The role of nutrients and dietary factors in attention-deficit hyperactivity disorder (ADHD) remains unclear.

Objectives: The primary objective was to evaluate the serum vitamin D level in children with a diagnosis of ADHD. The secondary objective was to detect the effect of vitamin D supplementation on cognitive function in those with vitamin D deficiency.

Methods: A total of 50 children with ADHD and 40 healthy controls were included in the study. We measured the serum level of vitamin D. Patients with vitamin D deficiency were subdivided into 2 groups: one with vitamin D supplementation and the other without vitamin D supplementation. Further assessment and follow-up of children with ADHD was done. The Wisconsin Card Sorting Test, Conners’ Parent Rating Scale, and Wechsler Intelligence Scale for Children were performed at baseline and follow-up in all cohorts with an ADHD diagnosis.

Results: The diagnosis of vitamin D deficiency was significantly greater in children with ADHD compared with the control group (P < 0.05). Children with ADHD had significantly (P = 0.0009) lower values of serum vitamin D (17.23 ± 8.98) than the control group(31.47 ± 14.42). The group receiving vitamin D supplementation demonstrated improvement in cognitive function in the conceptual level, inattention, opposition, hyperactivity, and impulsivity domains.

Conclusion: Vitamin D supplementation in children with ADHD may improve cognitive function.

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Tags: ADHD Intervention