Wondering about tuberculosis and Vitamin D in Australia – Nov 2013

Vitamin D and Vitamin D and tuberculosis: hope or hype?

Med J Aust 2013; 199 (10): 648-649. Doi: 10.5694/mja13.11174
Anna P Ralph, MPH, FRACP, PhD, Clinical Research Fellow1
Robyn M Lucas, MB ChB, PhD, FAFPHM, Associate Professor2
1 Global and Tropical Health, Menzies School of Health Research, Darwin, NT.
2 National Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT.

It may be worthwhile to test for and treat vitamin D deficiency in latent infection, but not in active TB

No abstract outside of the paywall

References:

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  • 2. MacLachlan JH, Lavender CJ, Cowie BC. Effect of latitude on seasonality of tuberculosis, Australia, 2002-2011. Emerg Infect Dis 2012; 18: 1879-1881.
  • 3. Ralph AP, Lucas RM, Norval M. Vitamin D and solar ultraviolet radiation in the risk and treatment of tuberculosis. Lancet Infect Dis 2013; 13: 77-88.
  • 4. Liu PT, Stenger S, Li H, et al. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 2006; 311: 1770-1773.
  • 5. Ralph AP, Kelly PM, Anstey NM. L-arginine and vitamin D: novel adjunctive immunotherapies in tuberculosis. Trends Microbiol 2008; 16: 336-344.
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  • 15. Talat N, Perry S, Parsonnet J, et al. Vitamin D deficiency and tuberculosis progression. Emerg Infect Dis 2010; 16: 853-855.
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  • 17. Royal College of Pathologists of Australasia. Use and interpretation of vitamin D testing. Position statement. May 2013. http://www.aims.org.au/documents/item/347 (accessed Sep 2013).
  • 18. Perterlik M. Vitamin D insufficiency and chronic diseases: hype and reality. Food Funct 2012; 3: 784-794.
  • 19. Michaëlsson K, Baron JA, Snellman G, et al. Plasma vitamin D and mortality in older men: a community-based prospective cohort study. Am J Clin Nutr 2010; 92: 841-848.
  • 20. Dror Y, Giveon SM, Hoshen M, et al. Vitamin D levels for preventing acute coronary syndrome and mortality: evidence of a nonlinear association. J Clin Endocrinol Metab 2013; 98: 2160-2167.
  • 21. Nielsen NO, Skifte T, Andersson M, et al. Both high and low serum vitamin D concentrations are associated with tuberculosis: a case-control study in Greenland. Br J Nutr 2010; 104: 1487-1491.
  • 22. Cannell J. Why should you keep your vitamin D level around 50 ng/ml? Vitamin D Council Newsletter 2011, 23 Sep.

See also VitaminDWiki

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