Simple vitamin D supplementation - daily, weekly, or monthly - Sept 2023


Supplementing Vitamin D in Different Patient Groups to Reduce Deficiency

Nutrients 2023, 15(17), 3725; https://doi.org/10.3390/nu15173725

  • Pawel Pludowski ORCID Department of Biochemistry, Radioimmunology and Experimental Medicine, The Children’s Memorial Health Institute, 04-730 Warsaw, Poland


Table of Contents
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Recommendations
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Introduction: Studies indicate a high prevalence of vitamin D deficiency in both the general population and at-risk groups. Given the association between vitamin D deficiency and various diseases, addressing this concern becomes crucial, especially in situations where routine monitoring is challenging.

Materials and methods: A systematic literature review of the current knowledge on vitamin D dosing in diverse at-risk populations and the application of the findings to a broader clinical perspective.

Results: The reviewed studies revealed a high prevalence of vitamin D deficiency among patients with musculoskeletal disorders, systemic connective tissue diseases, corticosteroid use, endocrine and metabolic conditions, malabsorption syndromes, obesity, chronic kidney disease, cancer, and central nervous system diseases. Vitamin D deficiency was often more severe compared to the general population. Higher dosages of vitamin D beyond the recommended levels for the general population were shown to be effective in improving vitamin D status in these at-risk individuals. Additionally, some studies suggested a potential link between intermittent vitamin D administration and improved adherence.

Conclusion: Simplified dosing could empower clinicians to address vitamin D deficiency, particularly in high-risk populations, even without routine monitoring. Further research is needed to establish the optimal dosing regimens for specific at-risk populations.
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Study does not mention that obese need far more Vitamin D

VitaminDWiki – Overview Obesity and Vitamin D contains:

See also: Weight loss and Vitamin D - many studies   Child Obesity and Vitamin D - many studies   Obesity, Virus, and Vitamin D - many studies
Obese need more Vitamin D
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  • Normal weight     Obese     (50 ng = 125 nanomole)

Click here for 2014 study

Obese need 2X to 3X more vitamin D - Nov 2014 has the following
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  • Normal weight     Obese     (50 ng = 125 nanomole)


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