Poor sleep if low Vitamin D, Magnesium, or Vitamin B6 (NHANES) – June 2019

Analysis of NHANES 2005-2016 Data Showed Significant Association Between Micro and Macronutrient Intake and Various Sleep Variables

Curr Dev Nutr. 2019 Jun 13;3(Suppl 1). pii: nzz031.P06-103-19. doi: 10.1093/cdn/nzz031.P06-103-19. eCollection 2019 Jun.

Note: there appears to be no study for this abstract

Ikonte C1, Reider C2, Fulgoni V 3rd3, Mitmesser S1.
1 Pharmavite LLC.
2 Pharmavite.
3 Nutrition Impact LLC.

OBJECTIVES: To understand the association between micro and macronutrient intake and sleep variables from the National Health and Nutrition Evaluation Survey (NHANES, 2005-2016).

METHODS:
Data analysis was performed using SAS 9.4; regression analysis was used to assess the relationship (p < 0.05) of nutrient intake with sleep variables. All nutrients were individual usual intakes determined using the National Cancer Institute method from food plus supplements; covariates included age, gender, ethnicity, poverty income ration, current smoking status and physical activity level. Individuals 16+ years of age were included in the analysis; pregnant or lactating females and those with unreliable dietary recalls were excluded in the analysis. Seven (7) Sleep variables included in the analysis were short sleep hours (<7 hrs of sleep) and trouble sleeping (NHANES 2005-2016), sleep disorder (NHANES, 2005-2014) and poor sleep quality, insomnia, sleep latency, and use of sleeping pills >5 times in the last month (NHANES 2005-2008).

RESULTS:
In adults (males and females) 19+ years,

  • 32.7% experienced short sleep;
  • 47.3% poor sleep quality;
  • 8.94% a sleep disorder;
  • 37.9% sleep latency;
  • 9.30% used sleeping pills;
  • 15.1% exhibited insomnia; and
  • 27.7% experienced sleep trouble.

Within this population, short sleep was significantly (p < 0.05) associated with the greatest number of nutrients; showing an inverse association with

  • magnesium,
  • niacin,
  • vitamin D,
  • calcium, and
  • dietary fiber intake.

Across all seven sleep variables, however,

  • magnesium,
  • niacin and
  • vitamin D

demonstrated significant (p < 0.05) inverse association within this population.
Inverse associations were also found for

  • dietary fiber intake and short sleep and sleep disorder;
  • phosphorus intake and poor sleep quality,
  • sleep latency and sleep pill use; and
  • vitamin K intake and poor sleep quality, sleep disorder, sleep latency and sleep pill use in the gender combined adults 19+ years.

Within this population however, there were direct associations for the intakes of protein and vitamin B6 and short sleep, sleep disorder and sleep trouble; for the intakes of sodium and vitamin A and poor sleep quality, sleep latency and sleep pill use; for the intake of vitamin B12 and poor ADL and insomnia; and for the intake of zinc and sleep quality, sleep latency, sleep pill use, poor ADL and insomnia.
Among female adults 19+ years, dietary fiber was the only nutrient that showed an inverse association with all seven sleep variables.

CONCLUSIONS: These findings demonstrate the importance of micro and macronutrient intake on numerous sleep variables.

FUNDING SOURCES: This analysis was funded by Pharmavite, LLC.

PMID: 31223980 PMCID: PMC6574146 DOI: 10.1093/cdn/nzz031.P06-103-19

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