Postgrad Med J. 2011 Aug;87(1030):514-8. Epub 2011 Apr 20.
Shivane VK, Sarathi V, Bandgar T, Menon P, Shah NS.
Department of Endocrinology, Seth G S Medical College, Parel, Mumbai, Maharashtra, India. drvijayasarathi at gmail.com
OBJECTIVE: Data on the prevalence of hypovitaminosis D in Indians living in the western part of the country are limited. The authors aimed to study the vitamin D status and dietary intake of calcium and phytates in healthy adult volunteers from a city in the western part of India.
METHODS: This cross-sectional study was conducted at a tertiary care centre in western India. A total of 1137 young (age: 25-35 years), healthy volunteers of both sexes were included in the study. All subjects were assessed for sun exposure, dietary intake of energy, protein, fat, calcium and phytates. Biochemical investigations included calcium, inorganic phosphorus, alkaline phosphatase, 25-hydroxyvitamin D (25(OH)D), intact parathyroid hormone (iPTH), total proteins, albumin and creatinine in serum and spot urinary calcium to creatinine ratio.
RESULTS: The serum 25(OH)D concentration for the whole study population was low (17.4±9.1 ng/ml), and that for men and women were 18.9±8.9 ng/ml and 15.8±9.1 ng/ml, respectively. Seventy per cent of the study population had hypovitaminosis D (25(OH)D <20 ng/ml) with a slightly higher prevalence in women (76%). Mean dietary calcium intake of the study population was 322.92±135.17 mg/day and was very low when compared with the recommended dietary allowance (400 mg/day for adults of both sexes) issued by the Indian Council of Medical Research. Dietary phytate was much higher than calcium intake with a dietary phytate to calcium ratio of 2.25±0.76. Serum iPTH had significant negative correlation with 25(OH)D (r=-0.23, p<0.001).
CONCLUSION: Hypovitaminosis D, low dietary calcium and high phytate consumption are highly prevalent among young healthy adults in the western part of India.
- Teens increasingly indoors - especially if dark skin - July 2010
- Rickets in 30 percent of infants in India who had low vitamin D – March 2011
- Low D in developing countries – less than 5 ng in some children in China – Oct 2010
- 70 percent of Koreans in their twenties had less than 20ng of vitamin D – Dec 2010
- Overview Deficiency of vitamin D
- All items: Deficiency of Vitamin D
- Red Alert – 30% of pre-teens in Tehran had less than 5 ng of vitamin D – Feb 2011
- Every hour of TV watched reduces your lifespan by 22 minutes – Aug 2011 probably the same for multi-media
- Teens increasingly indoors - especially if have dark skin
- 90 % of young health care professionals had less than 30 ng of vitamin D – Nov 2011 probably indoors too much latitude 47 degrees