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Vitamin D is needed before, during and after Pregnancy – May 2022


Vitamin D: Before, during and after Pregnancy: Effect on Neonates and Children

Nutrients 2022, 14(9), 1900; https://doi.org/10.3390/nu14091900
by José Luis Mansur 1,*ORCID,Beatriz Oliveri 2,Evangelina Giacoia 3ORCID, David Fusaro 4 and Pablo René Costanzo 5,*ORCID

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A worldwide high prevalence of vitamin D (VD) deficiency has become of growing concern because of potential adverse effects on human health, including pregnant women and their offsprings. Beyond its classical function as a regulator of calcium and phosphate metabolism, together with its fundamental role in bone health in every stage of life, its deficiency has been associated to multiple adverse health effects. The classic effects of VD deficiency in pregnancy and neonates have been late hypocalcemia and nutritional rickets. Nevertheless, recent studies have linked VD to fertility and 25(OH)D with several clinical conditions in pregnancy: preeclampsia, gestational diabetes, higher incidence of cesarean section and preterm birth, while in infants, the clinical conditions are low birth weight, lower bone mass and possible relationship with the development of such diseases as bronchiolitis, asthma, type 1 diabetes, multiple sclerosis and autism included as VD non-classical actions. The supplementation with Vitamin D and achievement of optimal levels reduce maternal-fetal and newborn complications. Supplementation in children with VD deficiency reduces the risk of respiratory infections and possibly autoimmune diseases and autism. This review emphasizes the roles of Vitamin D deficiency and the consequences of intervention from preconception to infancy.
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  • 126. Belderbos, M.E.; Houben, M.L.; Wilbrink, B.; Lentjes, E.; Bloemen, E.M.; Kimpen, J.L.L.; Rovers, M.; Bont, L. Cord blood Vitamin D deficiency is associated with respiratory syncytial virus bronchiolitis. Pediatrics 2011,127,1513-1520. [CrossRef]
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  • 130. Golan-Tripto, I.; Loewenthal, N.; Asher, T.; Dizitzer, Y.; Baumfeld, Y.; Goldbart, A. Vitamin D deficiency in children with acute bronchiolitis: A prospective cross-sectional case- control study. BMC. Pediatr. 2021, 21, 211. [CrossRef]
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  • 133. Khaled, S.; Nafisa, H.R.; El-Houfey, A.A.; El-Asheer, O.; Mohamed, S.A.A.; Ahmed, E.A.; Abdel Baseer, K.A.; Darwish, M.M. Trial of Vitamin D Supplementation in Infants with Bronchiolitis: A Randomized, Double-Blind, Placebo-Controlled Study. Pediatr. Allergy Immunol. Pulmonol. 2015, 28,102-106.
  • 134. Camargo, C.A., Jr.; Rifas-Shiman, S.L.; Litonjua, A.A.; Rich-Edwuards, J.W.; Weiss, S.T.; Gold, D.R.; Kleinman, K.; Gillman, M.W. Maternal intake of Vitamin D during pregnancy and risk of recurrent wheeze in children at 3 years of age. Am. J. Clin. Nutr. 2007, 85, 788-795. [CrossRef] [PubMed]
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VitaminDWiki - Pregnancy category contains

821 items in Pregnancy category

 - see also

VitaminDWiki - Healthy pregnancies need lots of vitamin D contains

Problem
ReducesEvidence
0. Chance of not conceiving3.4 times Observe
1. Miscarriage 2.5 times Observe
2. Pre-eclampsia 3.6 timesRCT
3. Gestational Diabetes 3 times RCT
4. Good 2nd trimester sleep quality 3.5 times Observe
5. Premature birth 2 times RCT
6. C-section - unplanned 1.6 timesObserve
     Stillbirth - OMEGA-3 4 timesRCT - Omega-3
7. Depression AFTER pregnancy 1.4 times RCT
8. Small for Gestational Age 1.6 times meta-analysis
9. Infant height, weight, head size
     within normal limits
RCT
10. Childhood Wheezing 1.3 times RCT
11. Additional child is Autistic 4 times Intervention
12.Young adult Multiple Sclerosis 1.9 timesObserve
13. Preeclampsia in young adult 3.5 timesRCT
14. Good motor skills @ age 31.4 times Observe
15. Childhood Mite allergy 5 times RCT
16. Childhood Respiratory Tract visits 2.5 times RCT

RCT = Randomized Controlled Trial


"Vitamin D before, during, and after pregnancy" was the original name of Overview Pregnancy and vitamin D


How much Vitamin D for optimal health

Note: The study on this page say >30 ng is needed


VitaminDWiki - Optimal Vitamin D studies in Pregnancy category

This list is automatically updated


Created by admin. Last Modification: Friday June 10, 2022 23:54:09 GMT-0000 by admin. (Version 15)

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