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Vitamin D and the Liver – Is it Correlation or Cause – April 2018

Nutrients 2018, 10(4), 496; doi:10.3390/nu10040496
(This article belongs to the Special Issue Changing Times for Vitamin D and Health)


Items in both categories Liver and Intervention are listed here: give vitamin D and see what happens

Items in both categories Liver and Meta-analysis are listed here: summary of trials

 Download the PDF from VitaminDWiki

Table 1. Potential direct and indirect mechanisms of effect of vitamin D in liver diseases.


Table 2. Selected intervention studies in liver disease and study parameters


Jeremy T. Keane 1, Harendran Elangovan 2, Rebecca A. Stokes 1,2 and Jenny E. Gunton 1,2,3,

  • 1 Centre for Diabetes, Obesity & Endocrinology, The Westmead Institute for Medical Research (WIMR), Westmead, Sydney, NSW 2145, Australia
  • 2 The Garvan Institute of Medical Research, The University of New South Wales (UNSW), Darlinghurst, Sydney, NSW 2010, Australia
  • 3 Faculty of Medicine and Health, The University of Sydney, Westmead Hospital, Westmead, Sydney, NSW 2145, Australia

Vitamin D is becoming increasingly accepted as an important physiological regulator outside of its classical role in skeletal homeostasis. A growing body of evidence connects vitamin D with hepatic disease. This review summarises the role of vitamin D in liver homeostasis and disease and discusses the therapeutic potential of vitamin D-based treatments to protect against hepatic disease progression and to improve response to treatment. While pre-clinical experimental data is promising, clinical trials around liver diseases have mostly been under-powered, and further studies will be required to clarify whether vitamin D or vitamin D analogues have beneficial effects on liver disease.

Created by admin. Last Modification: Wednesday August 1, 2018 19:26:32 GMT-0000 by admin. (Version 4)

Attached files

ID Name Comment Uploaded Size Downloads
9753 Vitamin D and the Liver—Correlation or Cause.pdf PDF 2018 admin 21 Apr, 2018 21:13 338.02 Kb 476
9752 Liver T2.jpg admin 21 Apr, 2018 21:11 114.44 Kb 391
9751 Liver T1.jpg admin 21 Apr, 2018 21:10 124.75 Kb 386
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