Maturitas: November 27, 2014, DOI: http://dx.doi.org/10.1016/j.maturitas.2014.11.018
R.M. Francisemail, T.J. Aspray, C.E. Bowring, W.D. Fraser, N.J. Gittoes, M.K. Javaid, H.M. Macdonald, S. Patel, P.L. Selby, N. Tanna
Download the PDF from VitaminDWiki.
There is growing interest in the importance of vitamin D in the maintenance of bone health and the prevention of falls and fractures. Although there is no universal consensus on the criteria for vitamin D deficiency, this is common in the UK, particularly in frail older people . This has resulted in a marked increase in requests for serum 25 hydroxyvitamin D (25OHD) estimation, but there has been confusion about the indications for these measurements, interpretation of the results and the management of vitamin D deficiency.
- For average adult
They do not mention dark skin, obese, pregnant, child, or senior
- “Serum 25OHD measurements are not recommended in asymptomatic healthy individuals with no evidence of bone disease.”
- >20 ng is sufficient for almost the whole population
- “Patients with a serum 25OHD above 50 nmol/L should be reassured and given advice on maintaining adequate vitamin D levels through safe sunlight exposure and diet. “
No suggestion about supplementing: just sunlight and diet
No comment about the cofactors REQUIRED for bone health
- “Vitamin D2 may be preferred by vegetarians and patients who wish to avoid vitamin D of animal origin because of religious or cultural beliefs”
They appear to be unaware of the availability of vitamin D3 made from plants
- “ Oral administration of vitamin D is recommended, because of unpredictable bioavailability and slower correction of vitamin D deficiency with intramuscular preparations (7,8).”
Appear to be unaware of topical, vaginal, sublingual, etc
- “Loading doses should provide a total of approximately 300,000 IU (7,500 µg) vitamin D, given either as weekly or daily doses.
Overview Loading of vitamin D has many other opinions on loading doses around the world
- “Maintenance treatment should be considered one month after loading, with doses equivalent to 800 to 2,000 IU”
half of seniors got ZERO improvement from 1600 IU
- The only references in the PDF after 2010 were to Vitamin D2 studies
- Overview Osteoporosis and vitamin D
- Vitamin D and Bone Health – UK National Osteoporosis Society – April 2013
- National Osteoporosis Society of UK declares that 12 ng of vitamin D is enough – June 2013 same group!
- European Osteo group recommends 20-50 ng of vitamin D – Jan 2013
- Is 50 ng of vitamin D too high, just right, or not enough
- Korea proposes vitamin D of 20 ng, but notes 20ng increases osteo by 50 percent – Oct 2012
- Vitamin D, K2, Magnesium, etc increase bone density when taking together– Jan 2012
- 30 to 50 ng of vitamin D is optimal – Central Europe consensus Sept 2013
- Dark Skinned adults need more than 45 minutes of UK summer sun daily – June 2013
- 8X higher Osteoporosis risk if high level of vitamin A, vitamin D important too – Feb 2013
- Overview - Bone Fractures
- Overview: Vitamin D and falling
- Hypothesis: increased bone mineral density needs protein, Ca, Mg, Vitamin D and K