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Traumatic Brain Injury recovery helped by injection of 100,000 IU of Vitamin D – March 2019

The Effect of Vitamin D Supplementation in Patients with Acute Traumatic Brain Injury

World Neurosurgery, online 20 March 2019, https://doi.org/10.1016/j.wneu.2019.02.244


This study used just a small injection of Vitamin D
Suspect they injected regular vitamin D into muscle or fat tissue
Expect faster response from injecting semiactivated or fully activated Vitamin D into the blood
100,000 IU of Vitamin D will raise the blood level a little bit
Loading doses of 400,000 and 600,000 IU of Vitamin D have been used >1 million times
   By the way - I take 100,000 IU of vitamin D every 4 days (founder of VitaminDWiki May 2019)

TBI appears to be prevented and/or treated by getting more vitamin D in the brain

Each of the following help, some combination should be really good

  1. Progesterone (VDR)
  2. Omega-3 (VDR)
  3. Resveratrol (VDR)
  4. Magnesium (VDR and blood)
  5. Vitamin D

Wonder which additonal VDR activators might also prevent/treat TBI

Vitamin D Receptor table shows what compensates for low VDR activation

Compensate for poor VDR by increasing one or more:

1) Vitamin D supplement  Sun
Ultraviolet -B
Vitamin D in the blood
and thus in the cells
2) MagnesiumVitamin D in the blood
 AND in the cells
3) Omega-3 Vitamin D in the cells
4) Resveratrol Vitamin D Receptor
5) Intense exercise Vitamin D Receptor
6) Get prescription for VDR activator
   paricalcitol, maxacalcitol?
Vitamin D Receptor
7) Quercetin (flavonoid) Vitamin D Receptor
8) Zinc is in the VDRVitamin D Receptor
9) BoronVitamin D Receptor ?,
10) Essential oils e.g. ginger, curcuminVitamin D Receptor
11) ProgesteroneVitamin D Receptor
12) Infrequent high concentration Vitamin D
Increases the concentration gradient
Vitamin D Receptor
13) Sulfroaphane and perhaps sulfurVitamin D Receptor
14) Butyrate especially gutVitamin D Receptor
15) BerberineVitamin D Receptor

Note: If you are not feeling enough benefit from Vitamin D, you might try increasing VDR activation. You might feel the benefit within days of adding one or more of the above
The risk of 40 diseases at least double with poor Vitamin D Receptor as of July 2019

Trauma and surgery category starts with the following

Trauma and Surgery category has 334 articles

Large dose Vitamin D before surgery was found to help by 35 studies
Vitamin D is needed before most surgeries – many studies and RCTs
4.8 X more likely to die within 28 days of ICU if low Vitamin D - Jan 2024
Sepsis is both prevented and treated by Vitamin D - many studies
Thyroidectomy and Vitamin D - many studies
Orthopaedic surgeries need Vitamin D – many studies
Cancer - After diagnosis   chemotherapy
TBI OR "Traumatic Brain Injury - 21 in title as of Sept 2022
Superbug (Clostridium difficile) Infections strongly associated with low vitamin D - many studies
Glutamine and Omega-3 have also been proven to help several traumas/surgeries
   Note: Vitamin D also prevents the need for various surgeries and Omega-3 prevents many concussions/TBI
Trauma and Surgery is associated with 22 other VitaminDWiki categories
  Such as loading dose 33, Mortality 23, Infant-Child 21 Intervention 19 Cardiovascular 13, Injection 13 in Sept 2022

 Download the PDF Sci-Hub via VitaminDWiki

Objective: To investigate the acute and long-term effects of vitamin D supplementation on the recovery of patients with traumatic brain injury (TBI).

A retrospective study was conducted involving 345 patients with TBI who visited a single trauma center. Vitamin D serum levels were measured without supplementation at admission, 1 month, and 3 months post-TBI (control group) from August to December 2016. From January 2017, vitamin D supplementation was provided to patients with TBI with low vitamin D serum levels at admission (supplement group). The outcomes were investigated by assessing performance function (Extended Glasgow Outcome Scale) and cognitive function (Mini-Mental Status Examination, and Clinical Dementia Rating) at 1 week and 3 months post-TBI.

The mean vitamin D serum level in patients with TBI at admission was 13.62 ± 9.01 ng/mL. The level significantly increased from 14.03 ± 8.68 ng/mL at admission to 37.42 ± 12.57 ng/mL at 3 months post TBI in the supplement group (P < 0.001). The cognitive outcomes (Mini-Mental Status Examination/Clinical Dementia Rating, P = 0.042/P = 0.044) and GOS-E score (total TBI, P = 0.003; mild-to-moderate TBI, P = 0.002) significantly improved from the first week to 3 months post TBI in the patients with vitamin D supplementation.

Administration of vitamin D supplements in mild-to-moderate TBI patients with significant vitamin D deficiency during the acute phase of the injury may improve long-term performance and cognitive outcomes. Therefore, the treatment strategies should be individually planned for the patients with TBI based on their baseline vitamin D level.

Created by admin. Last Modification: Tuesday February 23, 2021 16:10:59 GMT-0000 by admin. (Version 10)

Attached files

ID Name Comment Uploaded Size Downloads
11947 TBI.pdf admin 13 May, 2019 196.01 Kb 1118