- Response by Perplexity AI - Feb 2024
- Note: Probably little reduced response in seniors with Topical Vitamin D
- 13 reasons why many seniors need more vitamin D (both dose and level) - July 2023 has:
- VitaminDWiki -
4 studies in both categories Seniors and Noontime Sun - VitaminDWiki -
5 studies in both categories Seniors and UV - There have been
2351 visits to this page
Response by Perplexity AI - Feb 2024
Includes references, graphics, videos, etc.
Seniors synthesize less vitamin D from sun exposure due to several physiological and lifestyle factors. The primary reasons include:
- Decreased Skin Efficiency: As people age, the levels of the substance in the skin (7-dehydrocholesterol) that UVB light converts into the vitamin D precursor decrease. This results in a 50% reduction in the formation of previtamin D3 in older individuals compared to younger ones 2 3
- Renal Function Decline: Aging affects the formation of 1,25-dihydroxyvitamin D (calcitriol), the active form of vitamin D. There is a 50% reduction in the production of 1,25(OH)2D due to an age-related decline in renal function. Although serum 1,25(OH)2D levels are maintained in part by secondary hyperparathyroidism, the overall capacity to produce the active form of vitamin D diminishes with age 2
- Lifestyle Factors: Older adults may engage in less outdoor physical activity, reducing their exposure to sunlight, which is necessary for the skin to produce vitamin D 4
- Additionally, seniors might have dietary patterns that do not provide sufficient vitamin D 2
- Obesity: Fat tissue absorbs vitamin D, and studies have shown that being obese is correlated with low vitamin D levels. Since the prevalence of obesity can increase with age, this can further contribute to lower vitamin D synthesis in seniors 3
- Vitamin D Absorption and Metabolism: Conditions that affect the gut and digestion, such as celiac disease, chronic pancreatitis, Crohn's disease, and cystic fibrosis, can reduce vitamin D absorption. Moreover, some types of liver disease can reduce the absorption of vitamin D because the liver isn't producing normal amounts of bile, or essential steps in vitamin D metabolism can't occur or occur incompletely 3
- Sunscreen and Clothing: While sunscreen use and clothing are important for preventing skin cancer, they can also reduce the skin's ability to produce vitamin D from sunlight. Although the impact of sunscreen on vitamin D levels might not be significant due to irregular use, it's a factor worth considering, especially for seniors who might be more cautious about sun exposure 3
- In summary, seniors synthesize less vitamin D from sun exposure due to a combination of physiological changes, such as decreased skin efficiency and renal function decline, as well as lifestyle factors like reduced outdoor activity and dietary intake. These challenges highlight the importance of monitoring vitamin D levels in the elderly and considering supplementation or dietary adjustments as necessary.
Note: Probably little reduced response in seniors with Topical Vitamin D
Topical Vitamin D category contains;
Topical is one of the many ways of increasing the vitamin D in your body
Topical is 2X to 50X more expensive than oral form
Topical is great for those who not want to swallow pillls nor fortifiy their food/drink with Vitamin D
Topical is one of the many gut-friendly forms of vitamin D (good bioavailability for those with poor guts
Topical is especially good form to apply directly to skin problems:
- i.e. Psoriasis Warts Burns Acne Eczema Wounds (lasts about a day)
The skin, like most tissues of the body, can fully-activate Vitamin D locally - no liver nor kidney needed.
Provides perhaps 100X higher concentration of Vitamin D to that portion than if same dose were taken orally
There were 98 topical Vitamin D products on Amazon Sept 2024 Creams, oils, patches, nanoemulsions, etc.
I prefer Nutrasal nanoemulsion form
Suspect that topical Vitamin D is best absorbed where the skin gets Vitamin D naturally
- - - face and hands vs the back or the inside of arms
Nanoemulsions can also be applied topically under the tongue and inhaledAnd, some topical Vitamin D does not use the Kidneys
Getting Vitamin D into your body has a chart:
13 reasons why many seniors need more vitamin D (both dose and level) - July 2023 has:
- Senior skin produces 4X less Vitamin D for the same sun intensity
- Seniors have fewer vitamin D receptor genes as they age
Receptors are needed to get Vitamin D in blood actually into the cells - Many other Vitamin D genes decrease with age
- Since many gene activations are not detected by a blood test,
more Vitamin D is often needed, especially by seniors - Seniors are indoors more than when they were younger
not as agile, weaker muscles; frail, no longer enjoy hot temperatures - Seniors wear more clothing outdoors than when younger
Seniors also are told to fear skin cancer & wrinkles - Seniors often take various drugs which end up reducing vitamin D
Some reductions are not detected by a vitamin D test of the blood
statins, chemotherapy, anti-depressants, blood pressure, beta-blockers, etc - Seniors often have one or more diseases that consume vitamin D
osteoporosis, diabetes, Multiple Sclerosis, Cancer, ... - Seniors generally put on weight as they age - and a heavier body requires more vitamin D
- Seniors often (40%) have fatty livers – which do not process vitamin D as well
- Reduced stomach acid means less Magnesium is available to get vitamin D into the cells
- Vitamin D is not as bioavailable in senior intestines
- Seniors with poorly functioning kidneys do not process vitamin D as well
- Glutathione (which increases Vitamin D getting to cells) decreases with age
Seniors category has431 items
VitaminDWiki -
4 studies in both categories Seniors and Noontime Sun This list is automatically updated
VitaminDWiki -
5 studies in both categories Seniors and UV This list is automatically updated
- Seniors get about 4X less vitamin D from the sun or UVB
- Response to UV varies more with pigment genes and age than skin color – Jan 2019
- Risks and benefits of UV radiation in older people: More of a friend than a foe - May 2015
- Weekly UV almost doubled elderly Vitamin D levels – Dec 2010
- Recommendations to elderly- avoid UV but take vitamin D – May 2010
There have been
2351 visits to this page Seniors get about 4X less vitamin D from the sun or UVB1995 visitors, last modified 19 Apr, 2024, This page is in the following categories (# of items in each category)
- VitaminDWiki -