Toggle Health Problems and D

Respiratory tract microbiome and breathing problems

PubMed – 238 studies of Lung Microbiome in 2017


See also VitaminDWiki

Inhaled Vitamin D

Breathing category starts with the following

438 items in Breathing category

Breathing-related Overviews at VitaminDWiki:
Allergy   Lung Cancer   TB   Asthma  Influenza  Colds and flu
Pneumonia   Respiratory infections   COPD   Air Polution   Smoking   Cystic Fibrosis

See also web

Bacteria in Your Lungs? New Microbiome Study Shows How They Get There - Feb 2017


  • “Bacteria in the lungs may play a major role in disease — and health. Researchers have just mapped where the bacteria are and how they arrived, paving the way for more discoveries about the lung microbiome.”
  • “… evidence that most of the bacteria in the lungs of healthy people got there by way of microaspiration. In other words, they ride in on tiny droplets of saliva that made it from the microbe-filled mouth to the lungs”
  • “Unlike the gut, healthy lungs are an inhospitable environment for bacteria, with little nutrition and constant surveillance by the immune system.”
  • “We are probably all aspirating small amounts of bacteria constantly, and so long as our immune system is intact, they rarely make us sick.”
  • “He and colleagues have already found evidence that the lungs are filled with gut microbes in critically ill patients.”

Discovery of Gut Bacteria in Critically Ill Lungs May Change ICU Care= July 2016


Enrichment of the lung microbiome with gut bacteria in sepsis and the acute respiratory distress syndrome - July 2016

link  PDF $9 Readcube

The Role of the Bacterial Microbiome in Lung Disease – June 2013


Understanding Microbiome Effect on Immune Checkpoint Inhibition in Lung Cancer: Placing the Puzzle Pieces Together – May 2018

Over the past couple of years, human microbiome has received increasing attention as a regulator and predictor of response to the therapies of various diseases. It is speculated that manipulating gut microbiome can modify response to cancer immunotherapies as well. Through this review, we have critically analyzed our current understanding of gut microbiome as a modulator of immunotherapies in lung cancer, explained conflicting data, evaluated current gaps and extrapolated our present knowledge to generate directions for future investigations.

PMID: 29781826 DOI: 10.1097/CJI.0000000000000232

The microbiome and the lung.– Aug 2014

Ann Am Thorac Soc. 2014 Aug;11 Suppl 4:S227-32. doi: 10.1513/AnnalsATS.201402-052PL.
Cui L1, Morris A, Huang L, Beck JM, Twigg HL 3rd, von Mutius E, Ghedin E.

Investigation of the human microbiome has become an important field of research facilitated by advances in sequencing technologies. The lung, which is one of the latest body sites being explored for the characterization of human-associated microbial communities, has a microbiome that is suspected to play a substantial role in health and disease. In this review, we provide an overview of the basics of microbiome studies. Challenges in the study of the lung microbiome are highlighted, and further attention is called to the optimization and standardization of methodologies to explore the role of the lung microbiome in health and disease. We also provide examples of lung microbial communities associated with disease or infection status and discuss the role of fungal species in the lung. Finally, we review studies demonstrating that the environmental microbiome can influence lung health and disease, such as the finding that the diversity of microbial exposure correlates inversely with the development of childhood asthma.
 Download the PDF from VitaminDWiki

Lung microbiome in healthy and diseased individuals – July 2017

 Download the PDF from VitaminDWiki

Bacterial Topography of the Healthy Human Lower Respiratory Tract – Jan 2017

 Download the PDF from VitaminDWiki

The cystic fibrosis lung microbiome - Jan 2014

Link doi: 10.1513/AnnalsATS.201306-159MG.

Lung microbiota – Wikipedia May 2018


  • “The microbial communities are highly variable in particular individuals and compose of about 140 distinct families. The bronchial tree for instance contains a mean of 2000 bacterial genomes per cm2 surface”
  • “Changes in microbial community composition seem to play a role in progression of such pulmonary disorders as chronic obstructive pulmonary disease (COPD), asthma, and cystic fibrosis”

List of human microbiota – Wikipedia – May 2018

1 Whole-body distributed
2 Natural cavities
3 Skin
3.1 Hair follicles
4 External ear
5 Mucous membranes
6 Eye
7 Gastrointestinal tract
8 Respiratory tract
9 Urogenital tract
10 Vagina
11 Placenta
12 Uterus
13 Ovarian follicle
14 Male reproductive tract

Created by admin. Last Modification: Thursday June 21, 2018 00:18:02 GMT-0000 by admin. (Version 14)

Attached files

ID Name Comment Uploaded Size Downloads
9970 probiotic allergicrhinitis.pdf admin 18 Jun, 2018 15:27 300.63 Kb 557
9968 Bacterial Topography of the Healthy Human Lower Respiratory Tract.pdf admin 18 Jun, 2018 09:20 2.70 Mb 630
9967 Lung microbiome in healthy and diseased individuals.pdf admin 18 Jun, 2018 09:19 3.71 Mb 680
9966 The microbiome and the lung.pdf admin 18 Jun, 2018 09:19 949.04 Kb 731
9965 PubMed.jpg admin 18 Jun, 2018 09:12 1.76 Kb 469