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Folate in VitaminDWiki - many studies


31+ VitaminDWiki pages with FOLATE or FOLIC in the title

This list is automatically updated

Items found: 33
Title Modified
Vitamin D can be inside of a “trojan horse” nanoball made of folate, Cancer cells attrack folate – April 2024 20 Apr, 2024
Dementia (vascular) risk increase 60% if take Folate with other B vitamins - Dec 2023 16 Dec, 2023
Folate in VitaminDWiki - many studies 08 Jul, 2023
High dose vitamin D fights Folate gene changes by COVID, autoimmune, CVD, ALZ – Oct 2022 06 Oct, 2022
Folate and Vitamin B6 decrease mortality – May 2022 27 May, 2022
Important Role of Micronutrients during COVID-19 (Zinc, Vitamin D, C, Folate) – May 5, 2021 06 May, 2021
Higher vitamin D is associated with higher Folate or higher Vitamin B-12 – June 2020 13 Jul, 2020
Sweat types, folate, binding protein, lighter skin in females and Vitamin D – Jan 2020 19 Jan, 2020
Glyphosate (Roundup) kills both weeds and the microbes in your gut that produce Folate – July 2019 11 Jul, 2019
Autism risk reduced 2X by prenatal vitamins (Vitamin D or Folic) – Feb 2019 28 Feb, 2019
Dr. Coimbra discusses Vitamin D, Magnesium, Folic Acid, B12, Autism, Depression, etc – Sept 2018 24 Nov, 2018
Dr. Coimbra interview covering Vitamin D, Magnesium, Folate, Vaccines - Oct 2018 24 Nov, 2018
Neural tube defects more likely due to low vitamin D than low Folate – April 2017 15 Sep, 2018
Vitamin D is at least 100 X better than Folic Acid 01 Sep, 2018
Vitamin D is 100X better than folic acid during pregnancy 31 Aug, 2018
Autism 17 times more likely with excessive Folic Acid and B-12 (now added to bread) – May 2016 02 Aug, 2018
Off topic – Folate can be produced by micro-organisms, can avoid synthetic Folic Acid – Aug 2018 02 Aug, 2018
Off topic: Folic Acid - the horror story (for a small percentage of people) - Sept 2013 19 Apr, 2018
Omega-3, Vitamin D, Folic acid etc. during pregnancy and subsequent mental illness of child – March 2018 29 Mar, 2018
First-Episode Psychosis associated with low Vitamin D, Vitamin C and Folate – meta-analysis Nov 2017 22 Dec, 2017
Increased cows milk allergy if Folic acid or Folate added to vitamin D during pregnancy – June 2016 05 Apr, 2017
Folic acid reduces both premature births and neural tube defects – March 2017 05 Apr, 2017
Autism 17 times more likely with excessive Folate and B-12 (now added to bread) – May 2016 09 Jun, 2016
Autism 17X more likely when have excessive levels of Folate and B-12 – May 2016 12 May, 2016
Schizophrenia might be treated by folic acid, vitamin B12 and vitamin D – May 2014 02 Dec, 2015
Vitamin D, DHA, Folic, Iodine benefits during pregnancy – July 2012 14 Oct, 2015
Vitamin D and Folate fortification of foods - April 2012 25 Apr, 2015
Neural tube defects of pregnant mice reduced by Vitamin D (perhaps less Folate needed) – April 2015 25 Apr, 2015
Health professionals: about 10X more were using Vitamin D, fish oil, folic acid by 2006 – March 2014 13 Jun, 2014
Off topic – Making birth defects ‘preventable’ Folic acid and the politics of risk reduction - Nov 2013 21 Dec, 2013
Vitamin D is not a cardiovascular fad like Vitamins C, E, Folic Acid, selenium, beta-caroteen, etc. – Circulation Nov 2013 26 Nov, 2013
Hypothesis – Increasing Folate or vitamin D decreases probability of skin cancer – July 2012 02 Aug, 2012
Birth control pills could contain Folic acid and vitamin D - Sept 2010 13 Nov, 2010

The evolution of folate supplementation - from one size for all to personalized, precision, poly-paths - July 2023

J Transl Int Med . 2023 Jul 5;11(2):128-137. doi: 10.2478/jtim-2023-0087
Qiangqiang He 1 2, Jianping Li 3

Image
Folate is a crucial nutrient that supports physiological functions. Low folate levels is a risk factor for several diseases, including cardiovascular diseases and neural tube defects. The most used folate supplement is folic acid, a synthetic oxidative form, and folic acid grain fortification is a success story of public health. However, the metabolic conversion of folic acid to bioactive tetrahydrofolate requires several enzymes and cofactors. Therefore, these factors influence its bioavailability and efficacy. In contrast, 5-methyltetrahydrofolate is used directly and participates in one-carbon metabolism, and the use of 5-methyltetrahydrofolate as an alternative folate supplement has increased. The metabolism of 5-methyltetrahydrofolate is primarily dependent on the transmembrane transporter, reduced folate carrier (RFC), and the RFC gene SLC19A1 variant is a functional polymorphism that affects folate status indexes. Recent studies demonstrated that the expression of RFC and cystathionine β-synthase, another enzyme required for homocysteine clearance, increases significantly by supplementation with calcitriol (vitamin D3), suggesting that calcitriol intake promotes the bioavailability of folate and has synergistic effects in homocysteine clearance. The advancements in biomedical and cohort studies and clinical trials have enhanced our understanding of the critical roles of folate and the regulation of one-carbon metabolism. We anticipate that the field of folate supplementation is poised to evolve from one size for all to personalized, precision, poly-paths (3Ps), which is a critical measure to meet individual needs, maximize health benefits, and minimize side effects.
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VitaminDwiki - Vitamin D Cofactors in a nutshell table show the importance of each

Supplement  # of
studies
Increase D
to tissue
How
Often
Vitamin D 986+Most people do not
have enough anymore
N.A.daily to
2 weeks
Magnesium 365
Many people need Mg
Vit D consumes Mg
Muscle pain, Afib
30%Several
times
a day
Vitamin K 156
Hard bones, soft arteries115% 2 day
Omega-3 407
Synergistic with Vit D
Independent of Vit D
30? % 2 day
Calcium 226
Reduce or add Vit K 2 day
Zinc 90
immunity20 ?% if poor VDR 7 day
Boron 37
plants and animals need B+20% 7 day
Resveratrol 48
antioxidant >100% if poor VDRDaily
Glutathione10+master antioxidantImproves activation
of 5 Vit D genes
Daily?
Also    Vitamin C 55
  Iodine 32
  Iron 68
  Vitamin B12 59
 
Selenium 25   Folate 31

Attached files

ID Name Comment Uploaded Size Downloads
19769 Folate F1.jpg admin 08 Jul, 2023 100.90 Kb 199
19768 evolution of folate.pdf admin 08 Jul, 2023 801.07 Kb 125