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Children getting 60,000 IU monthly got to vitamin D level of 33 ng – Sept 2015

Efficacy and safety of a single monthly dose of cholecalciferol in healthy school children.

J Pediatr Endocrinol Metab. 2015 Sep 3. doi: 10.1515/jpem-2015-0187
Kuchay MS, Jevalikar GS, Mithal A, Mishra SK, Dang N.

This study aimed to evaluate the efficacy and safety of a single monthly dose of cholecalciferol in healthy school children.

A total of 118 children of class VI of a residential school were selected to receive vitamin D supplementation in the form of oral cholecalciferol 60,000 IU monthly. Serum calcium and 25-hydroxyvitamin D (25OHD) levels were estimated at 0 and 12 months. The proportion of subjects achieving vitamin D sufficiency was assessed.

The mean 25OHD levels increased significantly from 12.04±5.27 ng/mL at baseline to 32.6±7.05 ng/mL after 12 months of supplementation (p<0.001). None developed hypercalcemia.

Vitamin D supplementation in the doses of 60,000 IU monthly is a reasonable, safe and cost-effective regimen for children to attain and maintain vitamin D sufficiency.
 Download the PDF from Sci-Hub via VitaminDWiki

Note: Previous studies have found that the benefit decreases somewhat when dosing frequency is > 21 days.

50,000 every three weeks would probably be better, but not as easy to remember

Are these 6th grade children?
Dose is related to body weight.

See also VitaminDWiki

VitaminDWiki – Better than Daily contains
31 items in BETTER THAN DAILY category

Non-daily (Bolus) is better:

  1. Better compliance for everyone
    • Fewer opportunities to forget.
    • If happen to forget, just take the pill days or weeks later
    • Fewer times to have to take a pill - for those who dislike doing so
  2. Non-daily is better the ~20% who have a poor Vitamin D Receptor
    • A high concentration gradient is one of 14 ways to get past Vitamin D Receptor limitations
    • So, while 80% get no extra benefit from non-daily dosing, 20% will get an extra benefit

VitaminDWiki – Infant-Child category has 838 items and contains

Having a good level of vitamin D cuts in half the amount of:

Need even more IUs of vitamin D to get a good level if;

  • Have little vitamin D: premie, twin, mother did not get much sun access
  • Get little vitamin D: dark skin, little access to sun
  • Vitamin D is consumed faster than normal due to sickness
  • Older (need at least 100 IU/kilogram, far more if obese)
  • Not get any vitamin D from formula (breast fed) or (fortified) milk
    Note – formula does not even provide 400 IU of vitamin D daily

Infants-Children need Vitamin D

Attached files

ID Name Comment Uploaded Size Downloads
19682 Monthly school children.pdf admin 22 Jun, 2023 548.83 Kb 79