Proof that Vitamin D Works has the following summary
+Vitamin D prevents or treats 93 health problemsSurf to is.gd/proofvitd for updates or details
Select pink box in the upper right to select a language
Click on underlined items for details
Health Problem | Treat Prevent | Reduction by Vit D | RCT = Randomized Controlled Trial * = link to additional RCT CT = Clinical Trial | ||
Hypertension | T P | 149 to 142 mm Hg HT risk reduced 10X | RCT* *, 2400 IU. 100,000 IU* When Vitamin D > 40 ng | ||
Cardiovascular after attack | T | 32 % fewer deaths | CT 1000 IU | ||
Diabetes Type 1 | P | 85 % | 12,000 kids, 2000 IU | ||
Diabetes Type 2 | T | 62 % | RCT* CRP reduction, 4000 IU Injection is far better - RCT * RCT 50,000 IU/2weeks + probiotics RCT 5,000 IU daily 6 months | ||
Back Pain | T | 95 % reduced 50% | 5000/10000 IU 60,000 IU weekly | ||
Influenza | P | 90 % | RCT *, 2000 IU | ||
Falls | P | 50% | RCT, 100,000 IU monthly RCT with Meals on Wheels 2016 | ||
Hip Fractures | P | 30 % | RCT * 800 IU | ||
Rickets | P | 98 % | Turkey, 400 IU NOT RCT, given to all children | ||
Raynaud's Syndrome | T | 40 % | RCT, visual scale, 20000 IU Avg | ||
Menstrual pain | P | 76 % | RCT, 7000 IU Avg, 70% reduction 2018 PMS reduced by half | ||
Pregnancy risks | P | 50 % | RCT, 4000 IU | ||
C-section, unplanned | P | 50 % | RCT, 4000 IU, small study | ||
Low birth weight | P | 60 % | RCT * 1000 IU of D2 | ||
TB | P | 60 % | RCT, 800 IU | ||
Breast Cancer | P | 60 % | RCT, 1100 IU (2007) | ||
Rheumatoid Arthritis pain | T | 40 % | RCT, 500 IU, added to prescription | ||
Cystic Fibrosis | T | 75 % 2nd study improved | RCT, pilot 4X fewer deaths 250,000 IU RCT, pilot 8,200 IU | ||
Chronic Kidney | T | 90 to 70 PTH | RCT, 3500 IU, | ||
Respiratory Tract Infection | P | 63 % | 3 RCT, 4000 IU 1 year 2nd 2000/800 IU 20,000 IU weekly | ||
Lupus | T T | zero flares Pain reduced | Loading then 100,000 IU monthly, RCT too RCT 4,000 IU | ||
Sickle Cell | T | Less pain | RCT, up to 100,000 IU/week | ||
Leg ulcer healing | T | 4X faster | RCT, 50,0000 IU/week, small study | ||
Traumatic Brain Injury | T | 2X | RCT, 20,0000 IU/day with progesterone | ||
Parkinson's Disease | T | Stabilized | RCT, 1200 IU/day | ||
Multiple Sclerosis | P T | 68% 95% were CURED | RCT, 7100 IU prevent pre-MS ==> MS 20,000 to 140,000 IU/day | ||
Congestive Heart Failure | T | 90 % | RCT, 1000 IU infants (also: Adults, not RCT) | ||
Middle Ear Infection | P | 30 % | RCT, 1000 IU infants | ||
Gingivitis | T | 88 % | RCT, 2000 IU | ||
Muscle in seniors | T | 17 % more muscle | RCT, 4000 IU | ||
Antibiotic use when >70y | T | 47 % | RCT, 60,000 IU monthly | ||
Infants taller | Benefit | 1 cm tall | RCT, 50,000 IU weekly, for 8 weeks while pregnant | ||
Gestational Diabetes | T | Reduced 3X | RCT, 2 doses of 50,000 IU | ||
After Heart Attack | T | +6% ejection fraction | RCT, 800,000 IU one time | ||
Prostate Cancer | T | Fewer +cores | RCT, 4000 IU (2012) | ||
Asthma | P T | Reduced symptoms | RCT, 60K IU/month; RCT 50K IU/week Need good D at 4 weeks into preg. | ||
Depression | T | Reduced | RCT 300,000 IU injection RCT 1500 IU helped Prozac RCT 50,000 IU weekly, elderly | ||
Low vitamin D while breastfed | P | All infants > 20 mg | RCT, 5,000 IU | ||
Fibromyalgia | T | Half of many still has Fibro | RCT, 30-48 ng RCT 50K IU/week | ||
Hives, Chronic | T | Reduced 40% | RCT, 4000 IU added | ||
Cholesterol | T | Reduced 4 mg | RCT, 400 IU + Ca | ||
Weight Loss | T | lost 5 more lbs | RCT, 2000 IU +diet +exercise | ||
Gestational Diabetes | P | 40% | RCT * , 5,000 IU | ||
Chronic Obstructive Pulmonary Disease | T | 17X improvement | CT, 50,000 IU weekly RCT 100,000 IU monthly | ||
Asthma | T | 1/2 Asthma attacks | RCT >42 mg of vitamin D | ||
Quality of Life (QoL) | T | Nursing Home QoL | CT, 4,000 IU in daily bread | ||
Death of Critically Ill Patients | T | 20% increase in survivability | RCT 540 K IU loading than 90K monthly | ||
Restless Leg Syndrome | T | Score 26 ==> 10 | CT, Vitamin D dose size not stated in abstract | ||
Hepatitis-C | T | Aided normal drugs | RCT 2.000 IU | ||
Crohn's disease | T | improved when > 30 ng 2nd study fewer relapses | RCT 2,000 IU 10,000 IU RCT | ||
Pre-term birth | P | 2.5X decrease, also: fewer c-section & better Apgar | RCT 2,000 IU India | ||
Cluster headaches | T | CH eliminated in 60% | 10,000 IU, Mg, Omega-3, etc | ||
Autism | T | 80% improved | CT 300 IU/kg/day for 3 months | ||
PreDiabetes | T | ~20% reduced | RCT 60,000 IU/month | ||
Weight loss: Overweight and Obese | T | 12 lbs in 6 months | RCT 100,000 IU/month | ||
Sarcopenia = muscle loss | T | 27% increase | RCT 1,000 IU | ||
Growing Pains | T | 60% decrease | ~100,000 IU/month -NOT RCT 2nd study, similar results | ||
Osteoarthritis pain | T | 60% decrease | 50,000 IU/weekly - NOT RCT | ||
ALS | T | helped | 2,000 IU - NOT RCT, given to all | ||
Vertigo | T | 3X reduction if raised > 10ng | 600,000 IU load, then maint. NOT RCT, given to all | ||
Warts | T | 80% eliminated injection | NOT RCT 60,000 IU/injection | ||
Metabolic Syndrome | P | reduced 44% when VitD increased by 30 ng | NOT RCT, given to all | ||
Hay fever | P | reduced 48% | RCT 1,000 IU for 30 days | ||
Preeclampsia | P | Recurrance cut in half 3 RCT 3.6 X less likely if > 30 ng | 50,000 IU every 2 weeks 4,000 IU daily | ||
Blood cell cancer Multiple Myeloma | T | Survival 90% vs 50% | 10,000 IU/week NOT RCT, given to all | ||
Irritable Bowel Syndrome | T | Reduced | 3,000 IU spray RCT | ||
Urinary Tract Infection | P | 50% reduction | RCT 20,000 IU weekly | ||
Mite Allergy | P | 5X reduction | RCT 2,000 IU preg, 800 IU child | ||
Perinatal depression (depression near birth) | T | 50% reduction | RCT 2,000 IU for just a few weeks | ||
Vaginosis | T | 10X reduction | RCT 2,000 IU | ||
Eczema | T | Reduced | 2 RCT 1,600 IU | ||
Non-Alcoholic Fatty Liver Disease | T | Reduced | RCT 20,000 IU weekly | ||
Knee Osteoartiritis | T | Pain Reduced | RCT 60,000 IU monthly after loading dose | ||
Tuberculosis | T | Faster Recovery | RCT single 450,000 IU dose | ||
Stroke - Ischemic | T | Faster Recovery | RCT single 600,000 IU injection RCT single 300,000 IU injection | ||
Sepsis | T | Reduce ICU and Hospital length of stay by 7 days each | RCT 400,000 IU | ||
Trauma deaths | T | 50% fewer deaths | Vitamin D & Glutamine NOT RCT, given to all | ||
Hemodialysis patients | T | helped | 50,000 IU weekly NOT RCT, given to all | ||
Fatty liver - child | T | 2 X reduction | RCT Vitamin D & DHA | ||
Fatigue | T | Reduced | 100,000 IU single dose NOT RCT, given to all | ||
Sleep Disorders | T | Nicely treated | RCT 50.000 IU bi-weekly | ||
Pneumonia (Ventilator-associated) | T | RCT Death rate cut in half | 300,000 IU injection | ||
Infertile males | T | birth rate doubled | RCT 300,000 IU + maint | ||
Waist size | T | Waist size reduced 3 cm | 100,000 IU loading + maint for 6 months for those with Metabolic Syndrome NOT RCT, given to all | ||
Attention Deficient Hyperactivity Disorder | T | Reduced Reduced | RCT 3,000 IU for 12 weeks RCT 50,000 IU weekly | ||
Alcoholic liver cirrhosis | T | improved survival | 1,000 IU of vitamin D NOT RCT | ||
Diabetic nephropathy | T | Reduced HOMA-IR, FRS | RCT 50,000 IU weekly | ||
Ulcerative Colitis | T | Reduced 60% | RCT 50,000 IU nano daily for a week | ||
Obese weight loss | T | Lost 3X more pounds | $10 of Vitamin D added to calorie restriction & walking | ||
Endometriosis | T | Nicely treated | RCT 50.000 IU bi-weekly | ||
Diabetic Wounds | T | 4X more likely to heal | RCT 6,400 daily | ||
Alzheimer's | T | Often reverse | Each person gets a different amount of Vit D, Omega-3, B12, Iron, etc | ||
Autoimmune | P | Decrease 30% | RCT Vit D + Omega-3 | ||
Smoking | T | reduce problems | RCT 50,000 bi-weekly |
+
Diseases which are related due to vitamin D deficiency which contains the following list
+Some of the disease associations: Disease 1 ==> Disease 2 (both associated with low vitamin D- Statins ==> many diseases associated with low vitamin D update Jan 2012
- Parkinson, Alzheimer, Stroke ==>Hip fracture
- Parkinson's ==> Osteoporosis
- Low Grip Strength ==> Osteoporosis
- Immune System disease (CVID) ==> Osteoporosis
- COPD ==> Osteoporosis
- COPD ==> Bone Fracture 4.7 X
- COPD ==> osteoporosis, cardio., skeletal muscle, anemia, metabolic synd.
- HIV ==> Osteoporosis
- Prostate Cancer ==> Osteoporosis
- Atopic Dermatitis ==> Osteopenia 1.8 X
- Prostate Cancer ==> Melanoma
- Skin wrinkles ==> Fragile bones
- Depression ==> Fragile bones
- Depressed ==> 2x more Stroke
- Depression ==> Heart Disease 40% increase,, Forbes
- Depression + Stroke ==> death (3x)
- Depression ==> premature birth
96% increase in premature birth if anti-depressants in late pregnancy - Depression ==> Cognitive Decline
- Acne ==> Depression
- Depression <==> Diabetes
- Diabetes ==> Cognitive impairment
- Diabetes ==> Vertebral fracture in men only
- Diabetes ==> Rheumatoid Arthritis
- Diabetes ==> PCOS women
- PCOS ==> Diabetes
- Periodontitis + Low Vit D ==>Diabetes 2.8X
- Diabetes ==> Pancreatic Cancer
- Diabetes ==> Cancers
- Diabetes ==> Alzheimer's
- Diabetes ==> TB?
- Diabetes (T1) ==> Multiple Sclerosis
- Diabetes ==> Parkinson's
- Smoking ==> weak bones
- Dental problems==> depression (pregnancy)
- Endometriosis ==> Coronary Heast Disease 3X
- Pregnancy ==> dental problems
- Pregnancy ==>Restless Legs
- No molar ==> 12X increase in Breast Cancer
- Obesity ==> Diabetes
- Obesity <==> Multiple Sclerosis
- Obesity ==> Cognitive Decline
- Obesity ==> Psorasis
- Obesity ==> Cancer
- Obesity ==> Migraine Headache
- Aortic calcification==> Vertebral fracture
- Low vitamin D for various reasons ==> 9X Suicide
- Asthma ==> Heart Problems and death
- Kidney ==> Tooth loss (7x increase)
- Kidney Disease ==> Osteoporosis 2014 full text
- Multiple Sclerosis ==> Asthma 3X
- Multiple Sclerosis ==> 2.6X increased Migrane Headache, web, full text online
- Multiple Sclerosis ==> 2X more Fractures, web, full text online
- Multiple Sclerosis ==>>Fibromyalgia 2015
- Multiple Sclerosis ==> Diabetes (T1)
- Psoriasis ==> Metabolic Syndrome on the web
- Psoriasis ==> Metabolic Syndrome
- Psoriasis ==> Kidney Disease
- Psoriasis ==> Heart problems
- Psoriasis ==> Diabetes
- Psoriasis==> Osteoporosis
- Celiac Disease ==> Anemia, Psorasis
- Celiac Disease ==> poor bones Aug 2014
- Intestinal Failure (gut) ==> Low Bone Mineral Density
- Chronic Pancreatitis ==>Painful bones
- Rheumatoid Arthritis ==> Cardiovascular
- Rheumatoid Arthritis ==>Psorasis 3.6X
- IBD ==> Cancer
- Stroke ==> Hip Fracture
- Stroke ==> 2.4 X Parkinson's Disease
- Restless Legs <==> ADHD
- Schizophrenia ==> Depression
- Schizophrenia ==> Diabetes (3x increase)
- Sleep Apnea ==>Fatty Liver disease
- Sleep Apnea ==>Gout
- Gout ==> Depression 3.8 X
- Hepatitis-C ==> Cancers - liver, prostate, ?
- Hepatitis -C ==> peripheral arterial disease 12X increase if > 65 years old
- Vitiligo ==> thyroid problems 2013
- Rickets ==> Autism
- Autism ==> Poor Bones
- Epilepsy ==> Osteoporosis
- Rickets ==> Breathing
Overview Pregnancy and vitamin D has the following summary
IU | Cumulative Benefit | Blood level | Cofactors | Calcium | $*/month |
200 | Better bones for mom with 600 mg of Calcium | 6 ng/ml increase | Not needed | No effect | $0.10 |
400 | Less Rickets (but not zero with 400 IU) 3X less adolescent Schizophrenia Fewer child seizures | 20-30 ng/ml | Not needed | No effect | $0.20 |
2000 | 2X More likely to get pregnant naturally/IVF 2X Fewer dental problems with pregnancy 8X less diabetes 4X fewer C-sections (>37 ng) 4X less preeclampsia (40 ng vs 10 ng) 5X less child asthma 2X fewer language problems age 5 | 42 ng/ml | Desirable | < 750 mg | $1 |
4000 | 2X fewer pregnancy complications 2X fewer pre-term births | 49 ng/ml | Should have cofactors | < 750 mg | $3 |
6000 | Probable: larger benefits for above items Just enough D for breastfed infant More maternal and infant weight | Should have cofactors | < 750 mg | $4 |
Low cost cofactors for vitamin D has the following summary
Cofactor | How Much | Benefit Bone teeth, nails | Comments | Actual supplementation by admin of VitaminDWiki | Cents per day |
Calcium | <750mg | Yes | Is excess calcium harmful to health - 2010 | 0* = None: get from healthy food | 0 ¢ |
Magnesium | 100mg (element) | Yes | May increase response to Vitamin D by 30% Many other health benefits as well | 1/2 teaspoon of Magnesium Chloride ever 3 days Make it by adding hot water to bulk MgCl (1 to 1) also use topically on both knees nightly | ~2 ¢ |
Vitamin K2 | >100 ug | Yes | perhaps 100 ug/1000 IU of vitamin D | Super K - all three forms in 1 capsule | 20 ¢ |
Vitamin A | ? | maybe | need some, but too much is bad | 0* | 0 |
Boron | 10 mg | Yes | may increase D3 in blood by 25% | Daily in granola in the morning | 1 ¢ |
Silica | ? | Yes | Daily - Horsetail - buy in bulk Include in morning cereal | 1 ¢ | |
Omega-3 | 1 g or 1 Vectomega tablet | By increasing Vitamin D | helps health A LOT May increase active D | 1 Vectomega daily - VERY bioavailable | 75 ¢ |
Zinc | ? | ? | Needed by Vitamin D Receptor Thus results not seen in Vitamin D tests | take 30 mg tablet or liquid weekly | 3 ¢ |
Following are NOT cofactors | |||||
Poly fats | Ratio of types of fat | no | Almonds have the best fat ratio and they have Magnesium | daily mixed nuts | 5 |
Water | 2.5 liters/quarts | No | Help flush kidneys of any excess Calcium Perhaps only need this much Water if >10,000 IU | >1 quart per day, filtered | 0 |
Iodine | ?? micrograms | No | many people are deficient recently I am currently researching the topic | ~600 micrograms once a week | ~1¢ |
Sun | How much time varies with skin type, age, latitude, clothing, stand/lie . . | Yes | Probably better than vitamin D supplements | 30 minutes sun-nap 80 days/year UVB lamp in the winter | 0 |
Vitamin D | 2,000-15,000 | Yes | Proven to prevent/treat 76+ diseases | 12,000 IU avg - Winter (50,000 every 4 days) 10,000 IU avg - Summer 50,000 every 5 days) | 6 5 |
Overview Sports and vitamin D has the following summary
Athletes are helped by vitamin D by:
- Faster reaction time
- Far fewer colds/flus during the winter
- Less sore/tired after a workout
- Fewer micro-cracks and broken bones
- Bones which do break heal much more quickly
- Increased VO2 and exercise endurance Feb 2011
- Indoor athletes especially need vitamin D
- Professional indoor athletes are starting to take vitamin D and/or use UV beds
- Olympic athletes have used UV/vitamin D since the 1930's
- The biggest gain from the use of vitamin D is by those who exercise less than 2 hours per day.
- Reduced muscle fatigue with 10,000 IU vitamin D daily
- Muscle strength improved when vitamin D added: 3 Meta-analysis
- Reduced Concussions
See also: Sports and Vitamin D category254 items Overview Alzheimer's-Cognition and Vitamin D has the following summary
- FACT: Cognitive decline is 19X more likely if low vitamin D
- FACT: Dementia is associated with low vitamin D levels.
- FACT: Alzheimer’s 21 % more likely if low vitamin D
- FACT: Alzheimer's Disease is 4X less likely if high vitamin D
- FACT: Every single risk factor listed for Alzheimer's Disease is also a risk factor for low vitamin D levels
- FACT: Elderly cognition gets worse as the elderly vitamin D levels get even lower (while in senior homes)
- OBSERVATION: Reports of increased vitamin D levels result in improved cognition
- OBSERVATION: Alzheimer’s patients 3X more likely to have a malfunctioning vitamin D receptor gene – 2012
- OBSERVATION: Alzheimer's Disease has been seen to halt when vitamin D was added.
- OBSERVATION: Alzheimer’s is associated with all 7 of the genes which restrict vitamin D
- OBSERVATION: 39 vitamin D and Alz. or Cognition intervention trials as of Sept 2018
- OBSERVATION: 2 Meta-analysis in 2012 agreed that Alzheimer's Disease. associated with low vitamin D
- OBSERVATION: 50X increase in Alzheimer's while decrease in vitamin D
- OBSERVATION: Vitamin D reduces Alzheimer’s disease in 11 ways
- OBSERVATION: Alzheimer’s cognition improved by 4,000 IU of vitamin D
- OBSERVATION: Plaque removed in mice by equiv. of 14,000 IU daily
- OBSERVATION: DDT (which decreases Vit D) increases risk of Alzheimer's by up to 3.8X
- FACT: Vitamin D is extremely low cost and has very very few side effects
- CONCLUSION: Everyone concerned about cognitive decline or Alzheimer's Disease should take vitamin D
- PREDICTION: By 2024 Omega-3 and high dose Vitamin D will be found to reverse Alzheimer's in humans
- As of 2018 that combination has worked well with
- Other studies concerning Omega-3 include
- All items in category Cognition and vitamin D
324 - The End of Alzheimer's - if custom adjust Vitamin D, B-12, Iron, Omega-3, etc.
- Customizing the types of treatment to the individual results in reversing Alzheimer's
Autism treated by Vitamin D: Dr. Cannell - video June 2013 which includes reasons why Dr. Cannell believes Autism is related to Vitamin D (summarized by VitaminDWiki)
- Both have strong inheritance features – Vitamin D about 60%
- Both have gotten substantially worse in last 30 years
- Vitamin D is known to be involved in brain development
- All autistic children are VitD deficient, but not all children who are deficient are autistic: genes are involved
- When giving vitamin D to cure children of rickets “mental dullness” decreases as well
- Children with genes which give them too much (Williams Syndrome) have to reverse of autism – too sociable
- Mothers having lots of fish (and thus more vitamin D) give birth to kids with less autistic symptoms
- Both associated with weak bones
- Both worse around the age of weaning
- Autism is more common in rich families – more likely to apply sun screen and stay indoors
- Autism increases with drugs which lower levels of vitamin D
- Seizures are common with Autism - Vitamin D has been shown to reduce seizures
- Fewer autistic symptoms (such as sleep problems) during summer: when child gets more vitamin D from the sun
- Both worse with latitude
- Both vary with Ultraviolet light
- Both vary with time of year (more birth of autistics in March in Northern hemisphere)
- 2X more urban autism – less UVB in urban environments
- Both worse with pollution
- Both worse with increased clouds and rain
- Both worse with closely spaced pregnancies
- Autistics have abnormal immune response – similar to that of vitamin D deficiency
- Low levels of vitamin D in mother animals reduces brain function in offspring
- Vitamin deficient rat pups have similar brain abnormalities to that of human autistic children
- Autistic children get less vitamin D in their blood for the same amount of sun exposure
- The 4 males/1 female ratio - Note estrogen increases vitamin D in the brain (testosterone does not)
- Both worse in African Americans (A-A 2-3 increased autism rate)
- Both worse in Dark-skinned immigrants in Europe
- Note: All articles in Autism category
138 items Multiple Sclerosis and Vitamin D updates from Brazil
- Treatment with daily high doses of vitamin D Overcoming MS May 2013
Of course, this is not a cure it's a life-long treatment.. but at least it stops the progression and in many cases even revert back some (sometimes all) of the brain lesions. - Huge page - all in Portuguese about Coimbra's work
- Web site of patients who have been cured by Dr. Coimbra Australia 150 ng is the target
Great sequential posts, over a year. by an Australian patient whose MS was reversed by Dr. Coimbra - I Have Multiple Sclerosis: I Am Treating My MS With High Doses Vitamin D experienceproject. May 2013
Gives a fair amount of details, such as taking lots of water and monitoriing for excess Calcium.
Note A home test kit for excess Calcium in the urine is available $10 for 10 tests - Dr. Holick visited with the patients in Brazil Sept 2013
How often might 50,000 IU vitamin D be taken - results of clinical trials
Chart of Vitamin D levels vs disease - Grassroots Health June 2013 has the following chart
A few Vitamin D Overviews summaries11788 visitors, last modified 16 Dec, 2013, This page is in the following categories (# of items in each category) - Treatment with daily high doses of vitamin D Overcoming MS May 2013
- The End of Alzheimer's - if custom adjust Vitamin D, B-12, Iron, Omega-3, etc.