Vitamin D deficiency affects thyroid autoimmunity and dysfunction in iodine-replete area: Korea national health and nutrition examination survey
Endocrine, pp 1–8, Online: 21 September 2017
- 1.7 X more likely if just Vitamin D Deficient. Abstract does not indicate how much higher risk if person is also Iodine deficient
- Overview Thyroid and Vitamin D
- Vitamin D and Iodine are similar, and both are deficient and important to health
- Note: Many people in the US Mid-West had Goiter (enlarged Thyroid) before Iodine was added to US salt in the 1930’s
Note: Americans are now getting much less Iodine: salt is used less and salt in prepared foods is rarely iodized - All items in Thyroid and Parathroid category
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82 items in the category - See also Overview Hyperparathyroidism and vitamin D
- Overview Thyroid and Vitamin D
- PTH 4470 items as of Feb 2020
- "GRAVES DISEASE" 428 items as of Feb 2020
Mijin Kim, Eyun Song, Hye-Seon Oh, Suyeon Park, Hyemi Kwon, Min Ji Jeon, Won Gu Kim, Won Bae Kim, Young Kee Shong, Tae Yong KimPurpose
We evaluated the effects of vitamin D levels and iodine intake on thyroid autoimmunity and dysfunction in the Korean population.Methods
In this nationwide population-based study, data were obtained from the Korea National Health and Nutrition Examination Survey VI-1 and 2 (2013 and 2014), which was the first nationwide survey that measured both serum 25-hydroxy vitamin D [25(OH)D] levels and urinary iodine concentrations (UICs) in Korea. A total of 4181 participants who underwent laboratory tests for thyroid function, serum 25(OH)D levels, and UICs were included.Results
Anti-thyroid peroxidase antibody (TPOAb) positivity was more prevalent in the vitamin D deficient group (9.1%) than the vitamin D insufficient and sufficient groups (5.3% each; P = 0.016). The rate of TPOAb positivity was significantly higher in the iodine deficient group (P = 0.032). Thyroid dysfunction was significantly more prevalent in the iodine excessive group than in the other groups in total (P = 0.016) and TPOAb negative participants (P = 0.007). In the vitamin D deficient group, excessive iodine intake was significantly associated with high prevalence of thyroid dysfunction in total and TPOAb negative participants (P = 0.021 and P = 0.033, respectively). In the vitamin D insufficient and sufficient groups, association between thyroid dysfunction and iodine intake disappeared in total and TPOAb negative participants.Conclusions
This nationwide survey revealed a significant association between vitamin D deficiency and high prevalence of thyroid autoimmunity and dysfunction in participants with excessive iodine intake. Our findings might be helpful for elucidating the potential benefit of vitamin D supplements in TPOAb negative patients with excessive iodine intake.Publisher wants $40 for the PDF
Thyroid problems more than double when both Vitamin D and Iodine are low – Sept 2017(Cached) Printer Friendly Follow this page for updates4805 visitors, last modified 21 Sep, 2017, This page is in the following categories (# of items in each category)