Table of contents
- Prevalence of vitamin D deficiency among patients attending Post COVID-19 follow-up clinic: a cross-sectional study
- Opinion: Long-Haul needs both high dose vitamin D and re-activation of the Vitamin D Receptor
- Females in Egypt were more likely to get Long-Haul
- Vitamin D: A Role Also in Long COVID-19? - April 2022
Prevalence of vitamin D deficiency among patients attending Post COVID-19 follow-up clinic: a cross-sectional study
Eur Rev Med Pharmacol Sci . 2022 Apr;26(8):3038-3045. doi: 10.26355/eurrev_202204_28635.
A A R Mohamed Hussein 1, I Galal, M T Amin, A A Moshnib, N A Makhlouf, H A Makhlouf, H K Abd-Elaal, K M S Kholief, D A Abdel Tawab, K A Kamal Eldin, A M Attia, A E A Othman, J Shah, H Aiash
Objective: Post-COVID-19 syndrome appears to be a multi-organ illness with a broad spectrum of manifestations, occurring after even mild acute illness. Limited data currently available has suggested that vitamin D deficiency may play a role in COVID-19 cases. However, to our knowledge, no study has examined the frequency of vitamin D deficiency in post-COVID-19 cases and its effect on the symptom severity. The aim of this study is to both screen the frequency of vitamin D deficiency in post-COVID-19 syndrome patients and to study its relation to persistent symptoms.
Patients and methods: A cross-sectional, single-center study was conducted involving all cases attending post-COVID-19 follow-up clinic from November 2020 to May 2021. Complete history, clinical examination, and laboratory analysis [kidney functions, serum calcium, C-reactive protein, serum ferritin, Serum 25-(OH) vitamin D] was done as well as HRCT chest.
Results: The study included 219 post-COVID-19 cases, 84% had deficient vitamin D levels (< 20 ng/dL); 11.4% had insufficient level (20-30 ng/dL) and only 4.9 % reported normal level. There was no link between levels of vitamin D with either the acute or post-COVID-19 symptoms in the studied groups.
Conclusions: Despite the prevalence of vitamin D deficiency among the study population, no association was observed between the levels of vitamin D and post-COVID-19 symptoms. It appears that post-COVID-19 syndrome pathophysiology involves a more complex interaction with the immune system. Dedicated clinical trials are advised to better study vitamin D levels and the related disease severity in COVID-19 patients.
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Opinion: Long-Haul needs both high dose vitamin D and re-activation of the Vitamin D Receptor
- SARS-COV2 protects itself from Vitamin D by switching off the the Vitamin D Receptor
- When SARS-COV2 goes away, it fails to turn the Vitamin D Receptor back on
- A deactivated VDR leaves the cells with extremely low levels of vitamin D - which allows Epstein-Barr virus, etc to come out of hiding.
- Vitamin D Receptor activation can be increased by any of: Resveratrol, Omega-3, Magnesium, Zinc, Quercetin, non-daily Vit D, Curcumin, intense exercise, Ginger, Essential oils, etc Note: The founder of VitaminDWiki uses 10 of the 13 known VDR activators
Females in Egypt were more likely to get Long-Haul
perhaps due to excessive clothing