- Swiss in Spring 2020 with high zinc were 5X less likely to have COVID antibodies – April 2023
- COVID ICU half as likely if take 2 Zinc pills daily after enter Hospital - Nov 2022
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33 studies in both categories Virus and Zinc - VitaminDWiki -
6 studies in both categories Breathing and Zinc - Note: Zinc is required to get Vitamin D into cells (Via the Vitamin D Receptor)
- 4 additional studies of Zinc and COVID - with video talking about each of them
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26 studies in both categories Virus and Magnesium - VitaminDWiki – Zinc and Vitamin D category has
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Swiss in Spring 2020 with high zinc were 5X less likely to have COVID antibodies – April 2023
Association of plasma zinc levels with anti-SARS-CoV-2 IgG and IgA seropositivity in the general population: A case-control study
Clin Nutr . 2023 Apr 18;42(6):972-986. doi: 10.1016/j.clnu.2023.04.007
Antoine Equey 1, Mette M Berger 2, Semira Gonseth-Nusslé 1, Marc Augsburger 3, Serge Rezzi 4, Andrew C C Hodgson 4, Sandrine Estoppey 1, Giuseppe Pantaleo 5, Céline Pellaton 5, Maïwenn Perrais 3, Sébastien Lenglet 3, Valentin Rousson 1, Valérie D'Acremont 1, Murielle Bochud 1Introduction: Some micronutrients have key roles in immune defence, including mucosal defence mechanisms and immunoglobulin production. Altered micronutrient status has been linked with COVID-19 infection and disease severity. We assessed the associations of selected circulating micronutrients with anti-SARS-CoV-2 IgG and IgA seropositivity in the Swiss community using early pandemic data.
Methods: Case-control study comparing the first PCR-confirmed COVID-19 symptomatic cases in the Vaud Canton (May to June 2020, n = 199) and controls (random population sample, n = 447), seronegative for IgG and IgA. The replication analysis included seropositive (n = 134) and seronegative (n = 152) close contacts from confirmed COVID-19 cases. Anti-SARS-CoV-2 IgG and IgA levels against the native trimeric spike protein were measured using the Luminex immunoassay. We measured plasma Zn, Se and Cu concentrations by ICP-MS, and 25-hydroxy-vitamin D3 (25(OH)D3) with LC-MS/MS and explored associations using multiple logistic regression.
Results: The 932 participants (54.1% women) were aged 48.6 ± 20.2 years (±SD), BMI 25.0 ± 4.7 kg/m2 with median C-Reactive Protein 1 mg/l.
In logistic regressions, log2(Zn) plasma levels were negatively associated with IgG seropositivity (OR [95% CI]: 0.196 [0.0831; 0.465], P < 0.001; replication analyses: 0.294 [0.0893; 0.968], P < 0.05). Results were similar for IgA. We found no association of Cu, Se, and 25(OH)D3 with anti-SARS-CoV-2 IgG or IgA seropositivity.Conclusion: Low plasma Zn levels were associated with higher anti-SARS-CoV-2 IgG and IgA seropositivity in a Swiss population when the initial viral variant was circulating, and no vaccination available. These results suggest that adequate Zn status may play an important role in protecting the general population against SARS-CoV-2 infection.
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COVID ICU half as likely if take 2 Zinc pills daily after enter Hospital - Nov 2022
Twice daily oral zinc in the treatment of patients with Coronavirus Disease-19 A randomized double-blind controlled trial - Nov 2022
Clinical Infectious Diseases, ciac807, https://doi.org/10.1093/cid/ciac807
Saoussen Ben Abdallah, MD, Yosra Mhalla, MD, Imen Trabelsi, PhD, Adel Sekma, MD, Rim Youssef, MD, Khaoula Bel Haj Ali, MD, Houda Ben Soltane, MD, Hajer Yacoubi, MD, Mohamed Amine Msolli, MD, Nejla Stambouli, PhD ... Show more
BACKGROUND
Zinc supplementation has been considered one of the potential therapies for coronavirus disease-19 (COVID-19). We aimed to examine zinc efficacy in adult patients with COVID-19 infection.
METHODS
We conducted a prospective, randomized, double-blind, placebo-controlled, multicenter trial. Patients tested positive for COVID-19 without end organ failure were randomized to oral zinc (n = 231) or matching placebo (n = 239) for 15 days. The primary combined outcome was death due to COVID-19 or ICU admission within 30 days after randomization. Secondary outcomes included length of hospital stay for inpatients and duration of COVID-19 symptoms with COVID-19 related hospitalization for outpatients.
FINDINGS
One hundred ninety patients (40.4%) were ambulatory and 280 patients (59.6%) were hospitalized. Mortality at 30-day was 6.5% in Zinc group and 9.2% in Placebo group [odds ratio (OR) 0.70 (0.37-1.32)];
ICU admission rate was respectively 5.2% and 11.3% [OR 0.46 (0.23-0.88)].
Combined outcome was lower in zinc group compared to placebo group [OR 0.62 (0.38-0.99)]. Consistent results were observed in prespecified subgroups of patients with age < 65 years, those with comorbidity, and those who needed oxygen therapy at baseline. Length of hospital stay was shorter in zinc group compared to placebo group [difference 3.5 days, 95% CI (2.76-4.23)] in inpatients group; duration of COVID-19 symptoms decreased with zinc treatment compared to placebo in outpatients [difference 1.9 days, 95% CI (0.62-2.6)]. No severe adverse events were observed during the study.
INTERPRETATION
Our results showed that in COVID-19 patients, oral zinc can decrease 30-day death and ICU admission rate and can shorten symptoms duration.
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25 minute review of this study by Dr. Been - Dec 2022
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33 studies in both categories Virus and Zinc This list is automatically updated
- COVID was associated with low Vitamin D or Zinc – umbrella review Feb 2023
- 23 COVID mitigation strategies: at least 6 of which increase Vitamin D in cells - Sept 2022
- COVID and Zinc - many studies
- Surviving COVID with vitamins and minerals is not a myth – June 2022
- Vitamin D, Zinc, Magnesium etc. are needed to fight COVID – April 2022
- How vitamins D, C, Zinc, and Selenium might fight COVID - Dec 2021
- Nutritional supplementation during COVID hospitalization helped - RCT - Jan 2022
- COVID-19 decreased risk if add Vitamin D, A, C, NAC, Se, Zn, or Omega-3 – Dec 2021
- COVID-19 patients had low levels of Zinc, Vitamin A, Vitamin D, and Vitamin C – Sept 2021
- COVID-19 risk reduced 4X by each of: Vitamin D, Omega-3, Curcumin, Zinc (each increases D in cells)
- Vitamin D, C, A, and E, as well as Iron, Se, and Zinc each augment vaccine response – July 2021
- How Vitamin D, Magnesium, Omega-3 and Zinc prevent and treat COVID-19 etc. – June 2021
- COVID-19 treatment outside of hospital – Vitamin D, zinc, etc. – May 2021
- Important Role of Micronutrients during COVID-19 (Zinc, Vitamin D, C, Folate) – May 5, 2021
- Many supplements appear to fight COVID-19 – vitamin D cited 52 times – May 2021
- Zinc therapy for COVID-19 – Feb 2021
- COVID-19 alternative treatments - real-time database
- Overview of reviews of COVID-19 and vitamin D, etc. – April 2021
- COVID-19 what it is, prevention by Functional Nutrition doctor - Feb 2021
- Vitamin D, Zinc, etc. look promising for COVID-19 (Holick) - Jan 25, 2021
- Less than 10 dollars of Vitamin D per COVID-19 life saved in Myanmar - Jan 2021
- Micronutrients for COVID-19: Vitamin D, Vitamin C, Melatonin, Zinc, Se, etc. - Dec 2020
- Zinc (which increases vitamin D in tissues) may both prevent and treat COVID-19
- COVID-19 possible therapies: Vitamin D, Selenium, Zinc, Vitamin C, Potassium, Resveratrol , etc.– Aug 5, 2020
- 7 reasons to think that Zinc should fight COVID-19 – July 2020
- Observations that Vitamin D, Zinc, and Selenium separately reduce COVID-19 – Aug 7, 2020
- Mild COVID-19 quickly treated by Zinc lozenges in 4 people – June 6, 2020
- Zinc, respiratory tract infections and COVID-19 – July 2020
- Fight COVID-19 with Vitamin D, Vitamin C, Zinc, Selenium, Resveratrol, etc. - Sardi May 12, 2020
- Common cold prevented and treated by Vitamin D, Vitamin C, Zinc, and Echinacea – review April 2018
- Loss of smell may be related to low Zinc or perhaps low vitamin D
- Dengue fever immune response and micronutrients (vitamins D, E, A, and Zinc, Iron, Chromium) – Nov 2015
- Overview Colds and flu and Vitamin D
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6 studies in both categories Breathing and Zinc This list is automatically updated
- Zinc, respiratory tract infections and COVID-19 – July 2020
- Review of common cold (42 billion dollars) prevention and treatment - Zinc works – Feb 2014
- Common cold prevented and treated by Vitamin D, Vitamin C, Zinc, and Echinacea – review April 2018
- Loss of smell may be related to low Zinc or perhaps low vitamin D
- Infant wheezing 40 percent less likely if mother supplemented with vitamin D, vitamin E, or Zinc – meta-analysis Aug 2015
- Overview Colds and flu and Vitamin D
Note: Zinc is required to get Vitamin D into cells (Via the Vitamin D Receptor)
4 additional studies of Zinc and COVID - with video talking about each of them
- 1 - Zinc supplementation and COVID-19 mortality: a meta-analysis - 2022 PDF
- 5 studies: Reduction by 0.43
- 2 Zinc for Patients with COVID-19? Dec 2, 2022 PDF
- 3 _main article on this page
- 4 A Case-Control Study for the Effectiveness of Oral Zinc in the Prevention and Mitigation of COVID-19 - Sept 2021 PDF
- 5 How zinc can save 400,000 lives annually Sept, 2009 PDF
- Note: NOT COVID
VitaminDWiki - Vitamin D Receptor activation can be increased in 14 ways
Resveratrol, Omega-3, Magnesium, Zinc, Quercetin, non-daily Vit D, Curcumin, intense exercise, Butyrate Ginger, Essential oils, etc Note: The founder of VitaminDWiki uses 10 of the 14 known VDR activators
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26 studies in both categories Virus and Magnesium This list is automatically updated
- Long-COVID 3.1 X more likely if insufficient amounts of Magnesium and Vitamin D – March 2024
- COVID appears to be treated by many antioxidants (Vitamins D, C, E, K, and Quercetin, Curcumin, etc) – Jan 2023
- Fatigue and other long-haul problems appear to be associated with low Magnesium - Chambers Oct 2022
- Low Magnesium associated with severe COVID – many studies
- COVID and Magnesium - hypothesis, clinical trials, Long-Haul - Oct 2021
- COVID treatment patent applied for - using Rutin, Vitamin D, Vitamin C, Magnesium, etc. – April 2022
- COVID death 6.9X less likely if high Magnesium to Calcium ratio – April 2022
- Hypothesis: 2 long-haul COVIDs: had mild symptoms and had needed ICU - April 2022
- Excess Magnesium is bad for health (COVID hospital days in this case) – April 2022
- Vitamin D, Zinc, Magnesium etc. are needed to fight COVID – April 2022
- Long Covid, Short Magnesium - Chambers April 2022
- Lower Magnesium, 6 percent more COVID - Feb 2022
- Nutritional supplementation during COVID hospitalization helped - RCT - Jan 2022
- How Vitamin D, Magnesium, Omega-3 and Zinc prevent and treat COVID-19 etc. – June 2021
- Elderly nutrition and COVID-19 – systematic review July 2021
- Magnesium in Infectious Diseases in Older People - Jan 2021
- COVID-19 Cytokine storms attenuated by Vitamin D, Omega-3, Mg, Resveratrol, etc – April 2021
- 6X less risk of COVID-19 ICU if Vitamin D and Vit B12 and Mg – Jan 2021
- Cytokine storms (COVID-19, etc.) eliminated by Vitamin D (Magnesium helps)
- Magnesium and Vitamin D deficiencies associated with worse COVID-19 – Jan, 2021
- Excessive insulin decreases vitamin D in 4 ways – problems for diabetic COVID-19 – Dec 2020
- Magnesium (which increases vitamin D) may fight COVID-19 - Oct 2020
- COVID-19 1.8 X more likely if proton pump inhibitor (decreases Mg and Vitamin D) – Aug 2020
- COVID-19 might be treated with Mg IV and Potassium – July 2020
- COVID-19 prompts awareness of deficiencies of Vitamin D, C and Magnesium - April 6 2020
- Obesity pandemic since 1975 - is it due to Vitamin D, Magnesium, Iodine, adenovirus, or what
VitaminDWiki – Zinc and Vitamin D category has
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