Retinopathy Linked to Vitamin D Deficiency MedPageToday – with CME
- “In a meta-analysis that included 11 publications and involved studies that included about 6,000 individuals, diabetic patients with vitamin D deficiency were 26.7% more likely to have diabetic retinopathy than patients who were not deficient in the so-called sunshine vitamin (OR 1.267 [95% CI 1.168-1.373, P<0.001]), said Anawin Sanguankeo, MD, a resident in medicine at Bassett Medical Center, Cooperstown, N.Y.”
- . . “annual meeting of the American Association of Clinical Endocrinologists”
- “. . .mean difference of -2.25 ng/mL (95% CI: -3.64 to -0.87, P=0.001),”
- . . “vitamin D deficiency was defined as a serum level less than 20 ng/mL; optimal vitamin D level was defined as a serum level greater than 30 ng/mL.”
 Download the Abstract from VitaminDWiki Publisher wants $36 for the PDF http://dx.doi.org/10.1016/j.jcjo.2016.10.004
Meta-analysis published in 2017 - same 27%, probably the same meta-analysis
__Relationship between vitamin D deficiency and diabetic retinopathy: a meta-analysis
Jason Zhang, MD, Sikarin Upala, MD, MS'Correspondence information about the author MD, MS Sikarin UpalaEmail the author MD, MS Sikarin Upala, Anawin Sanguankeo, MD
DOI: http://dx.doi.org/10.1016/j.jcjo.2016.10.004 |
The purpose of this study was to evaluate the evidence for an association between diabetic retinopathy (DR) and vitamin D deficiency.
Design: Meta-analysis.
Methods: We included 14 observational studies with 10 007 participants who had undergone assessment for both DR and vitamin D deficiency. Pooled odds ratios (ORs) and 95% CIs were calculated using a random-effect, Mantel–Haenszel analysis.
Results: There was a statistically significant association between DR and vitamin D deficiency with an overall pooled OR of 1.27 (95% CI, 1.17–1.37; P = 0.001; I2 = 80%; Pheterogeneity = 0.01). There was also a statistically significant lower serum vitamin D level in patient subgroups with DR versus control groups, with an overall mean difference of –1.32 ng/mL (95% CI, –2.50 to –0.15; P = 0.001; I2 = 89%; Pheterogeneity = 0.01).
Conclusion: There is a statistically significant association between vitamin D deficiency and DR.
Publisher wants $36 for the PDF
See also VitaminDWiki
Diabetic Retinopathy associated with low Vitamin D - many studies
Overview Diabetes and vitamin D contains the following summary
- Diabetes is 5X more frequent far from the equator
- Children getting 2,000 IU of vitamin D are 8X less likely to get Type 1 diabetes
- Obese people get less sun / Vitamin D - and also vitamin D gets lost in fat
- Sedentary people get less sun / Vitamin D
- Worldwide Diabetes increase has been concurrent with vitamin D decrease and air conditioning
- Elderly get 4X less vitamin D from the same amount of sun
Elderly also spend less time outdoors and have more clothes on - All items in category Diabetes and Vitamin D
544 items: both Type 1 and Type 2 Vitamin D appears to both prevent and treat diabetes
- Appears that >2,000 IU will Prevent
- Appears that >4,000 IU will Treat , but not cure
- 90% less T2 Diabetes in the group having lots of Vitamin D
- Appears that Magnesium helps both Prevention and Treatment
- Many diabetics would be better treated if Gut-Friendly Vitamin D were used
Number of articles in both categories of Diabetes and:
'This list is automatically updated''- Dark Skin
24 ; Intervention 56 ; Meta-analysis 38 ; Obesity 35 ; Pregnancy 44 ; T1 (child) 39 ; Omega-3 11 ; Vitamin D Receptor 24 ; Genetics 13 ; Magnesium 29 Click here to see details Some Diabetes studies
- Type 2 Diabetes treated by Vitamin D (often 50,000 IU weekly) – meta-analysis July 2023
- Diabetic inflammation synergistically decreased by Vitamin D and exercise – RCT June 2022
- Incidence of Type-2 Diabetes increased 3X in 30 years (by the way, Vitamin D helps) – July 2022
- Vitamin d treats Type II Diabetes in many ways (14 article review) - Sept 2021
- T2 Diabetes 30 percent more likely if poor Vitamin D Receptor – meta-analysis of 47 studies – July 2021
- Diabetes helped somewhat by weekly 50,000 IU of vitamin D (5 ways to improve) – RCT Aug 2021
50 ng of Vitamin D fights Diabetes
- Saudi study defines normal Vitamin D level to be 50 to 70 ng (diabetes, etc.) - June 2020
- Diabetes 5X less likely if more than 50 ng of Vitamin D – April 2018
T1 Diabetes
- T1 Diabetes 3X lower risk if high vitamin D (over 40 ng) – Meta-analysis Nov 2020
- Type 1 Diabetes is prevented and treated by Vitamin D – review of 16 studies – Sept 2019
- Type 1 Diabetes prevention with Vitamin D and Omega-3 – Symposium April 2019
Pre-Diabetes
- 4X reduction in prediabetes progressing to T2D if more than 50 ng of vitamin D – RCT March 2023
- Prediabetes reduced by weekly 60,000 IU of Vitamin D – RCT Jan 2021
- Prediabetes 1.5 X more likely to go away if take Vitamin D – meta-analysis July 2020
Diabetes, Metabolic Syndrome and Magnesium - many studies
- All items in category Diabetes and Vitamin D
544 items - All items in category Vision and Vitamin D
109 items The items in both Diabetes and Vision are listed here:
- Retinopathy in males 6.9 X more likely if low vitamin D and low Magnesium - June 2024
- Diabetic Retinopathy associated with low Vitamin D - many studies
- Diabetic Retinopathy twice as likely if a T2 Diabetic has low level of vitamin D – meta-analysis March 2017
- Diabetic Retinopathy 2 X more likely if poor Vitamin D Receptor – meta-analysis Nov 2016
- Diabetic Retinopathy 27 percent more likely if low vitamin D – meta-analysis May 2016
- Diabetic Neuropathy sometimes can be reversed by vitamin D
- Worse diabetic vision is associated with low vitamin D or high PTH - Nov 2012
- Diabetics have more retina problems as they have less vitamin D – Sept 2011
Diabetic Retinopathy 27 percent more likely if low vitamin D – meta-analysis May 20165984 visitors, last modified 26 May, 2022, This page is in the following categories (# of items in each category) - All items in category Vision and Vitamin D