Association of vitamin D intake during pregnancy with small vulnerable newborns: a population-based cohort study
Food Funct. 2024 Jul 8. doi: 10.1039/d4fo01110d PDF behind paywall
Shanshan Wang 1, Gabriela Maria Villagrán Escobar 1, Ziyu Chen 1, Xiu Li 2, Guoping Xiong 3, Xuefeng Yang 1, Jian Shen 3, Liping Hao 1
Maternal vitamin D deficiency is common worldwide and has a significant impact on newborns. However, whether vitamin D intake during pregnancy is related to small vulnerable newborns (SVN) has not been confirmed. Thus, we sought to examine the relationship between maternal vitamin D intake, including vitamin D supplementation and dietary intake, and the risk of SVN. A total of 2980 Chinese mother-infant pairs were included in this study. Information on vitamin D supplementation and dietary intake was prospectively collected through face-to-face interviews. The outcomes assessed included low birth weight (LBW), preterm birth (PTB), small for gestational age (SGA), and SVN (having LBW, PTB, or SGA). Logistic regression models were used to evaluate the association of vitamin D intake with different types of SVN, and a restricted cubic spline function was modeled to explore their dose-response associations.
Compared to the lowest total vitamin D intake in the first trimester, the highest total vitamin D intake was associated with a 50.0% decrease in the SGA risk (OR: 0.50, 95% CI: 0.26, 0.96) and a 41.0% decrease in the SVN risk (OR: 0.59, 95% CI: 0.36, 0.95). Similar protective results were observed between vitamin D supplementation in the first trimester and SGA and SVN risks. Moreover, a significant L-shaped relationship was identified for total vitamin D intake, vitamin D supplementation, and dietary intake with the risk of different types of SVN. In conclusion, higher total vitamin D intake and supplementation in the first trimester were associated with a reduced risk of SGA and SVN.
23+ VitaminDWiki Pregnancy pages have BIRTH WEIGHT in the title
The list is automatically updated
Items found: 23
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Risk of low birth weight cut in half after taking lots of vitamin D while pregnant – July 2024 |
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08 Jul, 2024 |
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Diabetes 30% more likely in those with low birth weight - June 2023 |
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18 Jun, 2023 |
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Pregnancy problems (LBW, PTB, SGA) associated with low vitamin D, 42nd meta-analysis – March 2022 |
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24 Mar, 2022 |
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Pregnancies helped by Vitamin D (insulin and birth weight in this case) – meta-analysis Oct 2019 |
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05 Dec, 2021 |
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3.7X decrease in Very Low Weight Births (following huge increase in Vitamin D sales) - June 2020 |
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14 Aug, 2021 |
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Higher birth weight resulted in more fit adults (Vitamin D not mentioned) – Jan 2020 |
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04 Feb, 2020 |
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Low birth weight associated low Vitamin D (little sunshine in China in this case) - Dec 2019 |
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20 Jan, 2020 |
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Vitamin D cuts pregnancy risks in half – low birth weight, preeclampsia, gestational diabetes – Cochrane July 2019 |
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12 Sep, 2019 |
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Birth size and weight increased by Vitamin D – meta-analysis Feb 2019 |
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20 Feb, 2019 |
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Premature or low birth weight resulted in children 3X more likely to be anxious – meta-analysis May 2011 |
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25 Jan, 2019 |
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7X more likely to have low birth weight babies when mother very low on vitamin D – March 2010 |
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26 Nov, 2018 |
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Birth weight more than 9.9 lbs increases risk of breast cancer by 1.5 (wonder about Vitamin D) – Oct 2018 |
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13 Oct, 2018 |
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Vitamin D intervention reduces preterm births and low birth weight by 60 percent – Cochrane Reviews – Nov 2017 |
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07 Dec, 2017 |
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Strong decrease in both birth weights and pregnancy duration (concurrent with decrease in vitamin D) - Feb 2010 |
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20 Feb, 2017 |
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Birth weight and length increased with high levels of vitamin D – meta-analysis March 2015 |
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15 Dec, 2016 |
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Low vitamin D increased probability of low birth weight by 60 percent – meta-analysis June 2012 |
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13 Dec, 2016 |
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Less vitamin D makes for low birth weight for white babies - May 2010 |
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08 Dec, 2016 |
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Opening windows while pregnant cut the number of low birth weight infants by half – Feb 2013 |
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26 Dec, 2015 |
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Low birth weight associated with vitamin D levels less than 11 ng – Nov 2012 |
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26 Dec, 2015 |
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Low vitamin D pregnancy associated with both low birth weight and more weight in child later – July 2012 |
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18 Feb, 2015 |
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Low birth weight 3X more likely if mother had less than 25 nanograms of vitamin D – May 2012 |
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20 Sep, 2012 |
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Vitamin D given after low weight birth did not decrease death rate – May 2011 |
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23 Jun, 2012 |
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Low vitamin D results in severe preeclampsia and low birth weight – Mar 2011 |
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27 Nov, 2011 |