It appears that ~10% of people will benefit from Topical more than the Oral form of Vitamin D
It appears that ~20% of people having specific health problems will get more benefit from Topical than Oral
- Preeclampsia. Food Allergy, PTSD, Ear infection, Infertility, MS, Colon Cancer, TB, Asthma, COPD, Epilepsy, Atrial Fibrillation. Liver
- Also suspect for those people with poor guts: Cystic Fibrosis, Diabetes
However, Topical forms of Vitamin D are:
- 10X-100X more expensive
- Harder to use than oral for most people
- Do not easily allow high doses - for loading doses or non daily dosing (biweekly etc)
- Vitamin D cream might be OK - 5 squirts of cream = 50,000 IU
Most body tissues can fully activate Vitamin D locally (without the Liver and Kidneys)
Tissues such as the skin, the inside of the cheeks, the lungs, and the nose
Some people have a poor vitamin D binding gene
- Limits the amount of semi-activated Vitamin D from the liver
- The vitamin D binding gene does not appear to limit vitamin D that is activated by tissue
An increasing number of people have poor Vitamin D genes
- Starting in the 1930's people with poor immune systems have been surviving due to better hygiene, antibiotics, vaccines, etc.
- Since then, poor immune system genes have more frequently been passed on to future generations
- Before there was "Survival of the Fittest", but there is "Survival of the Survivors"
Table of contents
- Many reasons why vitamin D deficiency has become epidemic includes the following chart
- VitaminDWiki – Topical Vitamin D category contains
- Vitamin D Binding Protein category in VitaminDWiki has
177 items and starts with: - Getting Vitamin D into your body shows all of the sources
- TOP articles in Forms of Vitamin D:
- 4 Reasons why you have not heard that Vitamin D is good for the skin:
- There have been
13654 visits to this page
Many reasons why vitamin D deficiency has become epidemic includes the following chart
VitaminDWiki – Topical Vitamin D category contains
Topical is one of the many ways of increasing the vitamin D in your body
Topical is 2X to 50X more expensive than oral form
Topical is great for those who not want to swallow pillls nor fortifiy their food/drink with Vitamin D
Topical is one of the many gut-friendly forms of vitamin D (good bioavailability for those with poor guts
Topical is especially good form to apply directly to skin problems:
- i.e. Psoriasis Warts Burns Acne Eczema Wounds (lasts about a day)
The skin, like most tissues of the body, can fully-activate Vitamin D locally - no liver nor kidney needed.
Provides perhaps 100X higher concentration of Vitamin D to that portion than if same dose were taken orally
There were > 700 topical Vitamin D products on Amazon Aug, 2019
Creams. oils, patches, nanoemulsions, etc.
Suspect that topical Vitamin D is best absorbed where the skin gets Vitamin D naturally
- - - face and hands vs the back or the inside of arms
Nanoemulsions can also be applied topically under the tongue and inhaled
Topical Vitamin D sources include:
- Sun
- UV - sunbed or make UV lamp at home
- Topical Vitamin D oil
- Topical Vitamin D cream Amazon 10.000 IU Amazon 15,000 IU
- Topical Vitamin D water (open up and dissolve 50,000 IU powder in 1/2 tsp of water)
- Keep Vitamin D water under tongue for a few minutes
- Apply Vitamin D water to skin
- Spray inside of the cheek or on the skin Amazon 100+ companies Oct 2019
- Vitamin D patches Amazon, 5,000 IU in 8 hours
- Inhaled Vitamin D - make at home
Note: Topical Vitamin D may also be BETTER than most oral forms if you:- Have Gut problems
- Dislike swallowing pills
- Have a low/poor blood level response to vitamin D supplementation- e.g., poor CYP27A1 gene (in your liver)
- Have poor Vitamin D Binding Protein (in your blood)
Vitamin D Binding Protein category in VitaminDWiki has
177 items and starts with: Vitamin D Binding Protein (GC) gene can decrease the bio-available Vitamin D that can get to cells,
- GC is not the only such gene - there are 3 others, all invisible to standard Vitamin D tests
- The bio-available calculation does not notice the effect of GC, CYP27B1, CYP24A1, and VDR
- The actual D getting to the cells is a function of measured D and all 4 genes
- There is >2X increase in 8+ health problems if have poor VDBP (GC)
- It appears that VDBP only blocks oral vitamin D,
- but NOT Vitamin D from sun, UV, topical or inhaled (tissue activated)
- A clue: - Vitamin D from UV is 2X better for MS than oral Vitamin D
Vitamin D Binding Protein list of health problems includes:
Preeclampsia, Food Allergy, PTSD, Poor Response to Oral Vitamin D, Ear infection, Multiple Sclerosis, Colorectal Cancer, Prostate Cancer - blacks,
Infertility. TB, Asthma, COPD, Epilepsy, Atrial Fibrilation, and ObesityGetting Vitamin D into your body shows all of the sources
Note: Vitamin D Binding protein does NOT restrict topical or sublinqual Vitamin D
Mystery of why UVB is better than oral supplementation resolved after 7 years
- A 2012 study found that:
Vitamin D blood levels produced by UV were 2X better for MS than those from supplements - For years people speculated that the Sun/UVB produced something in addition to Vitamin D
- But, studies have found many health problems, such as MS. to be assocated with poor genes:
MS studies and Vitamin D Binding Protein (7 ), Vitamin D Receptor ( 12 ), Genes ( 22 ) - Mystery solved: Oral and topical sources will produce same blood level, but topical will get more activated vitamin D to the tissues if poor VDBP
Remaining mystery: Why does Vitamin D from UV last 2X longer in the body than from oral sources
- Might there be a better storage location for UV or topical Vitamin D in tissue (muscle?)
- Might non-UV, topical sources also have a 2X longer half-life in the body?
TOP articles in Forms of Vitamin D:
- Fat-soluble Vitamins go thru the slow lymph system
- Olive oil problem with Vitamin D (again) - Nov 2023
- Vitamin D which dissolves in mouth for those having poor response due to poor guts, HSCT etc.- June 2023
- Vitamin D: not one size, type, form, route for all - Jan 2022
- Nanoemulsion Vitamin D faster and better (paywall) – RCT Dec 2021
- Psoriasis paradigm shift – use topicals, like Vitamin D – Aug 2021
- Nanoemulsion Vitamin D is faster and better - many studies
- Vitamin D – food fortification around the world, types of microencapsulation – Feb 2020
- Nanoemulsion vitamin D is again found to be the best liquid form (for rats in this case) – June 2019
- Bioavailability of nanoemulsion formulations of Vitamin D3 – Nov 2019
- Topical Vitamin D provides more benefits than oral sometimes - many studies
- Vitamin D nanoemulsion etc. for fortification, pills, injections, topical and cancer – July 2019
- Vitamin D nanoemulsion corrected deficiency and improved bones in 1 week (high dose in rats) – Jan 2019
- Nanoemulsion Vitamin D may be a substantially better form
- The lungs can activate vitamin D locally – a Vitamin D inhaler may help lungs – Aug 2016
- Vitamin D sprayed inside cheeks (buccal spray) - several studies
- Getting Vitamin D into your body
- Topical vitamin D raised blood level to 38 ng (used Aloe Vera gel) – RCT March 2014
- Spray vitamin D inside cheek in case of emergency - Nov 2012
4 Reasons why you have not heard that Vitamin D is good for the skin:
1) Vitamin D has been patented to help the skin - and companies do not want to pay royalties
- WO/2006/133829 USE OF 25-HYDROXY-VITAMIN D3 - cream for many skin problems
- (WO/2006/094064) Sept 2006 METHOD OF REDUCING SCARS WITH VITAMIN D
- WO/2011/019617 VITAMIN D3 AND ANALOGS THEREOF FOR TREATING ALOPECIA - delivered to the skin March 2011
- Who said vitamin D could not be patented - VitaminDWiki
- A patent is one of the 22 Criteria to associate a health problem with low vitamin D in VitaminDWiki
2) FDA requires a LOT of data to allow a claim that a supplement can improve health
It appears to cost >$30,000 to prepare, present, and defend a single health claim for a supplement- FDA allows the claim that Vitamin D “supports healthy pregnancies and promotes full-term births” – Oct 2019
- FDA allows 2 specific Vitamin D and 2 Omega-3 health claims - 2019
3) Only recently have Vitamin D doses been large enough to really help (200X)
< year 2000 2019 increase Drops 10 IU/drop 2,000 IU 200X Capsule 200 IU 50,000 IU 250X 4) Doctors rarely suggest applying the Vitamin D directly to the skin
They often incorrectly believe that the Vitamin D must be first processed by the liver and the kidneys
There have been
13654 visits to this page Topical Vitamin D provides more benefits than oral sometimes - many studies7456 visitors, last modified 26 Jan, 2024, This page is in the following categories (# of items in each category)