The Impact of UV-dose, Body Surface Area Exposed and Other Factors on Cutaneous Vitamin D Synthesis Measured as Serum 25(OH)D Concentration: Systematic Review and Meta-analysis.
Anticancer Res. 2018 Feb;38(2):1165-1171, 10.21873/anticanres.12336
The face and hands produced 8X more vitamin D than other parts of the body
They are much more likely to have access to the sun than other parts of the body
It appears that there is a limit as to how much vitamin D can be produced at a time
per hour? per portion or day?, per day?
Study does not appear to discuss questions
1) Does increase UVA decrease the amount of Vitamin D generated?
2) Does UVA actually decrease existing levels of Vitamin D?
3) Is more Vitamin D generated when starting at a low vitamin D level (Spring)?
4) Is the amount of vitamin D generated a function of amount of body cholesterol?
5) Is the amount of Vitamin D generated a function of skin temperature?
6) Why is there a range of 5X in the amount of vitamin D generated between people?
even after accounting for skin color, obesity, and initial Vitamin D levels
See also VitaminDWiki
- Overview UV and vitamin D
- 3.3 X more likely to be Vitamin D deficient if wear long-sleeves – Oct 2022
- UVA causes skin cancer, perhaps UVB (Vitamin D) prevents skin cancer – Jan 2017
- More UV and vitamin D, less infectious disease – Jan 2017
- Vitamin D production after UVB exposure – A comparison of exposed skin regions – Feb 2015
- Sumilar conclusion was reached by the later study on this page
Noontime sun and D category starts with
Noontime sun and D hassee also
No – 10 minutes per day of sun-UVB is NOT enough
Vitamin D Myths - SUN
Optimize vitamin D from the sun
Overview Suntan, melanoma and vitamin D
Overview UV and vitamin D
50 ng of Vitamin D - 100 hours of noon sunbathing OR 3 dollars of Vit D
3.3 X more likely to be Vitamin D deficient if wear long-sleeves – Oct 2022
Sun and UV
Avoiding the sun may be as bad as smoking - many studies
Vitamin D from the sun without the heat (silver-coated plexiglass)
Opinion: sun better than UV better than vitamin D
Fewer cognitive problems if more sun or Vitamin D
Which Is Worse - Avoiding Sunlight or Vitamin D Deficiency – April 2019
Have We Gotten Sunscreen Totally Wrong - Jan 2019
People who get little noon-day sun must supplement with Vitamin D – systematic review June 2017
The Greatest Public Health Mistake of the 20th Century (sunscreen block Vitamin D) - 2017
Does Less Sun mean More Disease 5 minute video
340,000 US deaths annually due to insufficient sun (some due to low vitamin D) – July 2020
Health benefit of Sunlight is more than Vitamin D in the blood - many studies
5 Amazing Properties of Sunlight You've Never Heard About
Vitamin D and Sun conference – Germany June 2017
Cited by 27 studies as of Oct 2022
Download the PDF from VitaminDWiki
Jager N1,2, Schöpe J1,3, Wagenpfeil S1,3, Bocionek P4, Saternus R1,2, Vogt T1,2, Reichrath J5,2.
1 Center for Clinical and Experimental Photodermatology, The Saarland University Hospital, Homburg, Germany.
2 Department of Dermatology, The Saarland University Hospital, Homburg, Germany.
3 Institute for Medical Biometry, Epidemiology and Medical Informatics, Saarland University, Homburg, Germany.
4 Jörg Wolff Foundation, Stuttgart, Germany.
5 Center for Clinical and Experimental Photodermatology, The Saarland University Hospital, Homburg, Germany Joerg.reichrath at uks.eu.
BACKGROUND/AIM:
To optimize public health campaigns concerning UV exposure, it is important to characterize factors that influence UV-induced cutaneous vitamin D production. This systematic review and meta-analysis investigated the impact of different individual and environmental factors including exposed body surface area (BSA), UVB dose and vitamin D status, on serum 25(OH)D concentration.
MATERIALS AND METHODS:
In accordance with Preferred Reporting Items for Systematic Reviews and Meta-analyses, and Meta-analysis of Observational Studies in Epidemiology guidelines, a systematic literature search was conducted (MEDLINE; 01/1960-07/2016) investigating the impact of these factors on vitamin D status after artificial UV exposure as main outcome measure. Summary mean differences [and 95% confidence interval (CI)] were derived from random-effects meta-analysis to account for possible heterogeneity across studies. Meta-regression was conducted to account for impact of UVB dose, baseline 25(OH)D level and BSA.
RESULTS:
We identified 15 studies, with an estimated mean 25(OH)D rise per standard erythema dose (SED) of 0.19 nmol/l (95% CI 0.11-0.26 nmol/l). Results from meta-regression suggest a significant impact of UV dose and baseline 25(OH)D concentration on serum 25(OH)D level (p<0.01). Single UVB doses between 0.75 and 3 SED resulted in the highest rise of serum 25(OH)D per dose unit. BSA exposed had a smaller, non-proportional, not significant impact. Partial BSA exposure resulted in relatively higher rise compared to whole-body exposure (e.g. exposure of face and hands caused an 8-fold higher rise of serum 25(OH)D concentration/SED/1% BSA compared to whole-body exposure). Our findings support previous reports, estimating that the half-life of serum 25(OH)D varies depending on different factors.
CONCLUSION:
Our results indicate that partial BSA exposure (e.g. 10%) with moderate UV doses (e.g. 1 SED) is effective in generating or maintaining a healthy vitamin D status. However, due to limitations that include possible confounding factors such as skin type, which could not be considered, these findings should be interpreted with caution.
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