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Hypertension risk reduced 4X if adequate level of Vitamin D – July 2024


Vitamin D and the Risk of Developing Hypertension in the SUN Project: A Prospective Cohort Study

Nutrients 2024, 16(14), 2351; https://doi.org/10.3390/nu16142351
by Ana Valer-Martinez 1,2ORCID,Maira Bes-Rastrollo 1,3,4,*ORCID,Jose Alfredo Martinez 3,5,6ORCID,Miguel Angel Martinez-Gonzalez 1,3,4,7ORCID and Carmen Sayon-Orea 1,3,4,8

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Vitamin D deficiency has been associated with a higher risk of multiple diseases, including cardiovascular disorders. The purpose of this study was to examine the potential association between predicted levels of serum 25(OH)D and the risk of new-onset hypertension in a large Mediterranean cohort. A validated 136-item food frequency questionnaire was used as the dietary assessment tool. 25(OH)D serum levels were predicted using a previously validated equation. We performed Cox regression models to analyze the association between predicted serum 25(OH)D and the risk of hypertension, according to quartiles of forecasted vitamin D at baseline, after adjusting for multiple potential confounders. Over a median follow-up of 12.3 years, 2338 new cases of hypertension were identified.
The analyses revealed a significant inverse association between predicted serum levels of 25(OH)D at baseline and the risk of hypertension. Individuals in the highest quartile showed a 30% relatively lower risk of hypertension compared to the lowest quartile (hazard ratio (HR): 0.70; 95% confidence interval (CI): 0.60–0.80, p-trend < 0.001). The outcomes remained significant after performing sensitivity analyses. The findings suggested that higher levels of forecasted vitamin D are inversely and independently associated with the risk of incident hypertension, implying that vitamin D may offer protective benefits against the disease.
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VitaminDWiki – Hypertension category contains:

166 items in the category HYPERTENSION

see also
Overview Overview Hypertension and Vitamin D
Overview Cardiovascular and vitamin D
Overview Stroke and vitamin D
Incidence of 22 health problems related to vitamin D have doubled in a decade
Some interesting Hypertension studies

Attached files

ID Name Comment Uploaded Size Downloads
21445 Risk of hypertension.webp admin 21 Jul, 2024 15.19 Kb 87
21444 Hypertension 12 year_CompressPdf.pdf admin 21 Jul, 2024 341.81 Kb 48