- Conception is much more successful if BOTH female and male
have adequate amount of vitamin D (> 30 ng) - Testosterone levels are proportional to vitamin D levels - up to about 50 ng
- Birth rates doubled with Vitamin D - 300,000 for infertile men – RCT Nov 2017
- Infertility is higher in groups with low vitamin D - such as people with dark skins
(More Fertility/Sperm info below)
Learn how Vitamin D is essential for good health
Watch a 5 minute video "Does Less Sun Mean more Disease?"
Browse for other Health Problems and D in left column or here
see also Supplementing and More in the menu at the top of every page
If you have a disease associated with low Vit D take Vit D
Raising your Vit D levels will substantially prevent other low-Vit D health problems
Proof that Vitamin D Works Getting Vitamin D into your body
Books and Videos
Reasons for low response to vitamin D Why are doctors reluctant
Cancer studies include: Breast
Colds and flu Dark Skin
COVID-19 treated by Vitamin D - studies, reports, videos
See also:
Overview Women and Vitamin D
Overview Pregnancy and vitamin D Fertility and Vitamin D – several articles
Endometriosis
Ensure a healthy pregnancy and baby - take Vitamin D before conception
IVF OR "IN VITRO FERTILIZATION" etc. in 18 VitaminDWiki titles
- Vitamin D greatly improves Fertility
- 18+ VitaminDWiki pages have IVF or IN VITRO FERTILIZATION etc. in the title
-
7 Items in both of the categories Intervention AND Fertility/Sperm 142 Fertility items - 17+ VitaminDWiki Fertility pages have MALE or MEN or BOYS in the title
- Infertility is decreased by Vitamin D supplementation – meta-analysis Feb 2023
- Improved male fertility if increased Vitamin D and/or Calcium - Dec 2023
- Vitamin D is significantly associated with male fertility and sperm quality - meta-analyses 2019 and 2023
- 600,000 IU of vitamin D a few weeks for women before IVF did not help - RCT April 2021
- Clinical trial of 50,000 IU vitamin D weekly to improve IVF success - Phase 4 trial announced July 2017
- 59% reduction in sperm count around the world in just 40 years - Mercola Aug 2017. May 2022
- Eating more fish (probably Omega-3 and Vitamin D) resulted in a 16% increase in babies - May 2018
- Men Are Freaking Out About Their Sperm NYT July 2018
- Vitamin D: Study Finds Impaired Fertility - May 2016
- Why Are Young People Having So Little Sex? Nov 2018
- The Disappearing Y Chromosome Atlantic Mag Dec 2019
- 5X longer to induce pregnancy if male is >45
- Vitamin D in human reproduction: some answers and many more questions - Jan 2021
- Less fertile mice if low Vitamin D (fully-activated Vitamin D) - Feb 2021
- Email from a woman who read this page, tested and then took vitamin D - Dec 15. 2022
Vitamin D greatly improves Fertility
- Vitamin D is needed for human fertility – goal is 50 ng – Sept 2018
- In-vitro Fertilization costs at least 10,000 dollars, Vitamin D costs 5 dollars
- Women were 50X more likely to be fertile if just 1 ng higher level of vitamin D – Nov 2024
- Infertile patients 1.7X more-likely to become pregnant if take Vitamin D – meta-analysis Feb 2023
- Live birth 1.7 X more likely after IVF if good level of vitamin D – meta-analysis Aug 2020
- If diagnosed infertile, more likely to have live birth if Vitamin D fortification – Feb 2020
- Preconception vitamin D is great - every extra 10 ng associated with 10 percent more likely to have live birth – Aug 2018
- Women with more than minimum vitamin D were 3.4 X more likely to achieve pregnancy and 1.6 X more likely to have live births – June 2017
- Assisted Reproduction – 5 studies concluded vitamin D repletion helps – Review March 2015
- Pregnancy success increased 30 percent if sunny (or vitamin D) one month earlier – June 2015
- IVF 4X more successful for white women with lots of vitamin D – many studies
Increased male Vitamin D increases fertility
- Birth rates doubled with Vitamin D - 300,000 for infertile men – RCT Nov 2017
- Higher vitamin D results in 22% fewer abnormal sperm (Mendelian analysis) – May 2024
- Conception was 3.7X more likely if the male had a good level of Vitamin D – July 2022
- Far better sperm in fertility clinic if more than 30 ng of Vitamin D - June 2022
- Fertility (sperm) associated with vitamin D – meta-analysis Sept 2019
- Infertility - 71 percent of the time of BOTH partners had less than 20 ng of Vitamin D – Aug 2017
- Male fertility 4 X higher if high Vitamin D – Nov 2015
- Vitamin D somewhat assists reproduction – both the mother and the father – May 2014
Decreased Fertility if decreased Vitamin D Receptor
- Unexplained infertility 4X more likely if poor vitamin D receptor – Dec 2020
- Male Infertility is associated with poor Vitamin D Receptor – July 2021
18+ VitaminDWiki pages have IVF or IN VITRO FERTILIZATION etc. in the title
This list is automatcially updated
Items found: 20
7 Items in both of the categories Intervention AND Fertility/Sperm - In Vitro Fertilization clinical trial using 50,000 IU of Vitamin D bi-weekly – Dec 2024
- Sperm not improved enough by Vitamin D - 50,000 IU weekly for 8 weeks - RCT Aug 2020
- Women had better sexual desire, orgasm and satisfaction after Vitamin D supplementation – Feb 2018
- Testosterone and erectile function increased after vitamin D supplementation – Jan 2018
- Birth rates doubled with Vitamin D - 300,000 for infertile men – RCT Nov 2017
- Increased Testosterone and Erectile function, decreased weight with Vitamin D – March 2017
- Assisted Reproduction – 5 studies concluded vitamin D repletion helps – Review March 2015
142 Fertility items - wiki page:
- Women were 50X more likely to be fertile if just 1 ng higher level of vitamin D – Nov 2024
- Total Testosterone increased if take more than 4,000 IU vitamin D daily – meta-analysis Sept 2024
- In vitro Fertilization not helped if Vitamin D is slightly above 30 ng (need 50 ng) – July 2024
- Embryo implantation for mice helped by Vitamin D, should help women – July 2024
- Women have conception problems when vitamin D levels are less than 24 ng – meta-analysis May 2024
- Weight loss drugs increase unplanned pregnancies (perhaps due to Vitamin D) - May 2024
- Higher vitamin D results in 22% fewer abnormal sperm (Mendelian analysis) – May 2024
- In vitro fertilization and Vitamin D – many studies
- 90% in US have chlormequat chloride (pesticide) in urine – reduces fertility – Feb 2024
- More fertility associated with higher vitamin D - Dec 2023
- Infertility not associated with vitamin D (virtually none had more than 30 ng) - Dec 2023
- Infertile women have low vitamin D – Sept 2023
- Infertility risk increased 2.5 X by poor Vitamin D Receptor – July 2023
- Infertile women had less Vitamin D (Baghdad in this case) – June 2023
- Vitamin D improves Infertility in 9 ways (50 references, PDF behind paywall) – May 2023
- Infertile patients 1.7X more-likely to become pregnant if take Vitamin D – meta-analysis Feb 2023
- Unknown cause (idopathic) for male Infertility appears to be low vitamin D (9 X) – Sept 2022
- PCOS also fought by Magnesium combinations – review Aug 2022
- Conception was 3.7X more likely if the male had a good level of Vitamin D – July 2022
- Better sperm associated with higher vitamin D (again) – April 2022
- Fertility is a function of vitamin D around each egg (follicular fluid) – many studies
- Far better sperm in fertility clinic if more than 30 ng of Vitamin D - June 2022
- In vitro fertilization is more successful when vitamin D in ovaries, not just blood, is increased – April 2022
- Conception 1.5 X more likely if taking any amount of Omega-3 – Feb 2022
- In vitro fertilization NOT helped by 600,000 IU of vitamin D – RCT Sept 2021
- 3X more pregnancies when Vitamin D levels are high (assisted reproduction, women only) – Oct 2021
- Vitamin D levels in cells, not blood, is important (IVF follicular fluid in this case) – Aug 2021
- Pregnancy loss 9X more likely if male had less than 20 ng of Vitamin D – July 2021
- Pregnancy loss 9X more likely if male had less than 20 ng of Vitamin D – July 2021
- Male Infertility is associated with poor Vitamin D Receptor – July 2021
- Poor male fertility is association with poor Vitamin D Receptor (less D to the cells) – July 2021
- Vitamin D and Male Fertility Review – April 2020
- Low Vitamin D decreases fertility and increases subsequent autism, ADHD, etc – Feb 2018
- Unexplained infertility 4X more likely if poor vitamin D receptor – Dec 2020
- In Vitro Fertilization clinical trial using 50,000 IU of Vitamin D bi-weekly – Dec 2024
- Sperm not improved enough by Vitamin D - 50,000 IU weekly for 8 weeks - RCT Aug 2020
- Live birth 1.7 X more likely after IVF if good level of vitamin D – meta-analysis Aug 2020
- If diagnosed infertile, more likely to have live birth if Vitamin D fortification – Feb 2020
- Boys who were born Small for Gestational age are 1.9X more likely to be infertile – Dec 2019
- Conception within 6 months 3X more likely if high vitamin D – Oct 2019
- Fertility (sperm) associated with vitamin D – meta-analysis Sept 2019
- Poor ovarian response (poor IVF) associated with low vitamin D – Sept 2019
- Vitamin D associated with 60 percent better assisted reproduction success – Dec 2019
- In-vitro Fertilization costs at least 10,000 dollars, Vitamin D costs 5 dollars
- Fertility of men and women reduced by obesity and low vitamin D (perhaps synergistically) – June 2019
- Infertility treatment needs to achieve at least 30 ng of vitamin D – May 2019
- Natural pregnancy 4X more likely if sperm had a lot of CYP24A1 – April 2019
- Infertile women 10 percent more likely to die (perhaps due disease associated with low vitamin D – Nov 2017
- Perhaps vitamin D reduces DNA fragmentation of sperm – 2021
- Sexual disfunction treated by 300,000 IU of Vitamin D – RCT Nov 2018
- The role of vitamin D in male fertility, A focus on the testis – Sept 2017
- Premature ejaculation associated with low vitamin D – 2018, 2019
- Vitamin D is needed for human fertility – goal is 50 ng – Sept 2018
- Omega-3 helps conception as well as pregnancy – many studies
- Preconception vitamin D is great - every extra 10 ng associated with 10 percent more likely to have live birth – Aug 2018
- Ensure a healthy pregnancy and baby - take Vitamin D before conception
- Better erection associated with better Vitamin D – July 2018
- The earlier the better- preconception vitamin D - June 2018
- Infertility - 71 percent of the time of BOTH partners had less than 20 ng of Vitamin D – Aug 2017
- Many fertilization and pregnancy problems associated with low vitamin D in Saudi Arabia – April 2018
- Poor fertility in both women and men associated with low vitamin D – review Feb 2018
- Women had better sexual desire, orgasm and satisfaction after Vitamin D supplementation – Feb 2018
- Fertility of defrosted sperm better if had increased dietary Omega-3 – many studies
- Fertility improved with vitamin D supplement, unsure if low D causes low fertility – Jan 2018
- Testosterone and erectile function increased after vitamin D supplementation – Jan 2018
- Vitamin D - Effects on Human Reproduction, Pregnancy, and Fetal Well-being – Dec 2017
- IVF 60 percent more successful if woman had sufficient vitamin D – Dec 2017
- IVF 50 percent more likely to result in pregnancy if high vitamin D – meta-analysis Nov 2017
- Birth rates doubled with Vitamin D - 300,000 for infertile men – RCT Nov 2017
- Infertility is also associated with poor Vitamin D Binding Protein – Oct 2017
- Women with PCOS 4 X more likely to develop T2 Diabetes (no surprise, both associated with low vitamin D) - Aug 2017
- Global sperm count dropped by 59 percent in 40 years – meta-analysis Aug 2017
- Testosterone 14% higher in those with high vitamin D – Aug 2016
- Fertility marker (Anti-Müllerian Hormone) improved in a week by a single dose to 50,000 IU of vitamin D – RCT July 2017
- Increased Testosterone and Erectile function, decreased weight with Vitamin D – March 2017
- Women with more than minimum vitamin D were 3.4 X more likely to achieve pregnancy and 1.6 X more likely to have live births – June 2017
- Vitamin D and aspects of female fertility (especially PCOS) – May 2017
- The Role of Vitamin D in Reproductive Health—A Trojan Horse or the Golden Fleece – 2015
- Vitamin D and Human Reproduction – 51 page chapter – April 2017
- Sexual frequency down 20 percent in 20 years (decreased vitamin D not mentioned) March 2017
- Vitamin D2 improved sexual hormones, erectile function etc – Jan 2017
- Association between vitamin D and sperm parameters: Clinical evidence – Dec 2016
- Many fertility disorders associated with low vitamin D, still unsure how much is needed – Dec 2016
- PCOS (polycystic ovary syndrome) 4 times more likely if poor Vitamin D Receptor – Dec 2015
- Poor female sexual function associated with low vitamin D in pilot study – Aug 2016
- Vitamin D, athletes, hormones – June 2016
- In vitro fertilization not helped by vitamin D if ignore high levels and male levels – meta Mar 2016
- More surviving offspring if mother had high vitamin D (sheep in this case) – Jan 2016
- Male fertility 4 X higher if high Vitamin D – Nov 2015
- Low fertility associated with low Calcium intake and low vitamin D – Nov 2015
- Increased fertility (ovarian reserve, FSH) associated with higher levels of vitamin D – March 2015
- Vitamin D and pregnancy – review Nov 2015
- Testosterone levels increased after vitamin D supplementation (342 from 320) – June 2015
- Pregnancy success increased 30 percent if sunny (or vitamin D) one month earlier – June 2015
- Assisted Reproduction – 5 studies concluded vitamin D repletion helps – Review March 2015
- Vitamin D and fertility – Lerchbaum 2012, 2014
- High Testosterone is associated with higher vitamin D in soldiers – April 2015
- Assisted Reproduction might be aided by Vitamin D – review Dec 2014
- Erectile Dysfunction and vitamin D - many studies
- In Vitro Fertilization (D5 SET ICSI) 40 percent more successful if high vitamin D – Sept 2014
- Low testosterone is associated with levels higher than 40 ng of vitamin D (U-shaped)– July 2014
- Feel sexier with vitamin D and-or sunshine
- Vitamin D somewhat assists reproduction – both the mother and the father – May 2014
- Fertility in both women and men improves with more vitamin D (but less than 50 ng for men) – Dec 2013
- Infertility rate is 2X higher for blacks than whites (no mention of vitamin D, nor the man) – April 2014
- Fertility and Vitamin D – several articles
- Male fertility is improved in many ways by vitamin D – Jan 2014
- Vitamin D protects against many types of health problems – review May 2013
- PCBs increased the chance of being Vitamin D deficient by 3 percent – May 2013
- Male infertility associated with low vitamin D levels – Dec 2012
- Testosterone, vitamin D and inflammation – March 2013
- Fertility and sperm
- 130% more piglets after giving gilt Calcidiol, a form of vitamin D – Nov 2012
- IVF 4X more successful for white women with lots of vitamin D – many studies
- Semen worse when vitamin D lower than 20 or higher than 50 ng – Oct 2012
- Testosterone levels related to vitamin D levels up to 30 ng – July 2012
- Reproduction function in males improved by vitamin D – review Aug 2012
- Fertility problem (PCOS) reduced by vitamin D, etc: many studies
- Gonad hormone is associated with vitamin D level in adults– July 2012
- Hypothesis: increased vitamin D will increase erections and decrease CVD – June 2012
- Swine with extra vitamin D more likely to get pregnant and have more and larger piglets – June 2012
- Vitamin D and fertility: a systematic review – May 2012
- How 60 ng of vitamin D enabled pregnancy - a personal story
- Vitamin D associations with erectile dysfunction - April 2012
- Vitamin D - roles in women's reproductive health - Nov 2011
- Overview Women and Vitamin D
- Off topic - the cost of being female
- Hypothesis – Fatigue the day after sex is due to deficiency of Vitamin D, Magnesium, and Zinc
- More vitamin D associated with better sperm – May 2011
- Clinical Trial vitamin D levels and IVF success – May 2011
- Vitamin D and fertility and birth problems with dark skin – Jan 2011
- Testosterone increased 20 percent with daily 3332 IU vitamin D – RCT Dec 2010
- Epileptics have problems with conception - Oct 2010
- Higher vitamin D and 2X higher testosterone in summer than winter – Aug 2010
- Conception and vitamin D
- Vitamin D deficiency and pregnancy - from preconception to birth Aug 2010
- Overview Pregnancy and vitamin D
- Better sperm if have higher level of vitamin D
17+ VitaminDWiki Fertility pages have MALE or MEN or BOYS in the title
The list is automatically updated
Items found: 17
Infertility is decreased by Vitamin D supplementation – meta-analysis Feb 2023
__Influence of Vitamin D supplementation on reproductive outcomes of infertile patients: a systematic review and meta-analysis++
Reprod Biol Endocrinol. 2023; 21: 17doi: 10.1186/s12958-023-01068-8
Xiangqian Meng,1 Jiayao Zhang,2 Qi Wan,1 Jihua Huang,3 Tingting Han,3 Ting Qu,corresponding author#3 and Lin-lin Yucorresponding author#4Background
Low vitamin D status has been associated with an increased risk for infertility. Recent evidence regarding the efficacy of vitamin D supplementation in improving reproductive outcomes is inconsistent. Therefore, this systematic review was conducted to investigate whether vitamin D supplementation could improve the reproductive outcomes of infertile patients and evaluate how the parameters of vitamin D supplementation affected the clinical pregnancy rate.Methods
We searched seven electronic databases (CNKI, Cqvip, Wanfang, PubMed, Medline, Embase, and Cochrane Library) up to March 2022. Randomized and cohort studies were collected to assess the reproductive outcomes difference between the intervention (vitamin D) vs. the control (placebo or none). Mantel-Haenszel random effects models were used. Effects were reported as odds ratio (OR) and their 95% confidence interval (CI). PROSPERO database registration number: CRD42022304018.Results
Twelve eligible studies (n = 2352) were included: 9 randomized controlled trials (RCTs, n = 1677) and 3 cohort studies (n = 675). Pooled results indicated that infertile women treated with vitamin D had a significantly increased clinical pregnancy rate compared with the control group (OR: 1.70, 95% CI: 1.24–2.34; I2 = 63%, P = 0.001). However, the implantation, biochemical pregnancy, miscarriage, and multiple pregnancy rates had no significant difference (OR: 1.86, 95% CI: 1.00–3.47; I2 = 85%, P = 0.05; OR: 1.49; 0.98–2.26; I2 = 63%, P = 0.06; OR: 0.98, 95% CI: 0.63–1.53; I2 = 0%, P = 0.94 and OR: 3.64, 95% CI: 0.58–11.98; I2 = 68%, P = 0.21). The improvement of clinical pregnancy rate in the intervention group was influenced by the vitamin D level of patients, drug type, the total vitamin D dosage, the duration, administration frequency, and daily dosage of vitamin D supplementation. The infertile women (vitamin D level < 30 ng/mL) treated with the multicomponent drugs including vitamin D (10,000–50,000 IU or 50,000–500,000 IU), or got vitamin D 1000–10,000 IU daily, lasting for 30–60 days could achieve better pregnancy outcome.Conclusion
To the best of our knowledge, this is the first meta-analysis systematically investigated that moderate daily dosing of vitamin D supplementation could improve the clinical pregnancy rate of infertile women and reported the effects of vitamin D supplementation parameters on pregnancy outcomes. A larger sample size and high-quality RCTs are necessary to optimize the parameters of vitamin D supplementation to help more infertile patients benefit from this therapy.
 Download the PDF from VitaminDWiki
Improved male fertility if increased Vitamin D and/or Calcium - Dec 2023
Calcium and vitamin D homoeostasis in male fertility
Proceedings of the Nutrition Society, Page 1 of 14 doi:10.1017/S002966512300486X
Sam Kafai Yahyavi1,2, Ida Marie Boisen1,2, Zhihui Cui1,2, Mads Joon Jorsal1,2, Ireen Kooij1,2,
Rune Holt1,2, Anders Juul3,4,5 and Martin Blomberg Jensen1,2Calcium and vitamin D have well-established roles in maintaining calcium balance and bone health. Decades of research in human subjects and animals have revealed that calcium and vitamin D also have effects on many other organs including male reproductive organs. The presence of calcium-sensing receptor, vitamin D receptor, vitamin D activating and inactivating enzymes and calcium channels in the testes, male reproductive tract and human spermatozoa suggests that vitamin D and calcium may modify male reproductive function. Functional animal models have shown that vitamin D deficiency in male rodents leads to a decrease in successful mating and fewer pregnancies, often caused by impaired sperm motility and poor sperm morphology. Human studies have to a lesser extent validated these findings; however, newer studies suggest a positive effect of vitamin D supplementation on semen quality in cases with vitamin D deficiency, which highlights the need for initiatives to prevent vitamin D deficiency. Calcium channels in male reproductive organs and spermatozoa contribute to the regulation of sperm motility and capacitation, both essential for successful fertilisation, which supports a need to avoid calcium deficiency. Studies have demonstrated that vitamin D, as a regulator of calcium homoeostasis, influences calcium influx in the testis and spermatozoa. Emerging evidence suggests a potential link between vitamin D deficiency and male infertility, although further investigation is needed to establish a definitive causal relationship. Understanding the interplay between vitamin D, calcium and male reproductive health may open new avenues for improving fertility outcomes in men.
 Download the PDF from VitaminDWiki
Vitamin D is significantly associated with male fertility and sperm quality - meta-analyses 2019 and 2023
The association between serum vitamin D, fertility and semen quality: A systematic review and meta-analysis - Nov 2019
International Journal of Surgery Vol 71, Nov 2019, Pages 101-109https://doi.org/10.1016/j.ijsu.2019.09.025 FREE PDF
The Association between Serum Vitamin D Levels and Male Fertility: A Systematic Review and Meta-Analysis - Aug 2023
Andrologia Vol 2023 | Article ID 9002938 | https://doi.org/10.1155/2023/9002938 FREE PDF
600,000 IU of vitamin D a few weeks for women before IVF did not help - RCT April 2021
Single oral dose of vitamin D3 supplementation prior to in vitro fertilization and embryo transfer in normal weight women: the SUNDRO randomized controlled trial
American Journal of Obstetrics and Gynecology, https://doi.org/10.1016/j.ajog.2021.04.234Background: Improving in vitro fertilization (IVF) success is an unmet need. Observational studies suggested that women with deficient or insufficient vitamin D have lower chances of success, but whether supplementation improves clinical pregnancy rate is unclear.
Objective: To determine whether oral vitamin D3 supplementation may improve clinical pregnancy in women undergoing an IVF cycle
Study design: The SUNDRO trial is a two-centers randomized superiority double-blind placebo controlled trial. Subjects were recruited between October 2016 and January 2019. Participants were women aged 18-39 years with low vitamin D (peripheral 25-hydroxyvitamin D < 30 ng/ml), serum calcium ≥ 10.6 mg/dl, body-mass index (BMI) 18-25 Kg/m2, anti-mullerian hormone (AMH) levels > 0.5 ng/ml, starting their first, second, or third treatment cycle of conventional IVF or intracytoplasmic sperm injection (ICSI). The primary outcome was the cumulative clinical pregnancy rate per cycle. Pregnancies obtained with both fresh or frozen embryo transfers were included. Clinical pregnancy was defined as intrauterine gestational sac with viable fetus. The primary analysis was performed according to the intention to treat principle and could also include natural conceptions. Secondary outcomes included total dose of gonadotropins used, embryological variables (number of oocytes retrieved, number of suitable oocytes retrieved, fertilization rate and rate of top quality embryos) and clinical outcomes (miscarriage rate and live birth rate).
Results
630 women were randomized 2-12 weeks prior to initiate the IVF cycle to receive either a single dose of 600,000 IU of vitamin D3 (n=308) or placebo (n=322). One hundred thirteen (37%) and 130 (40%) women achieved a clinical pregnancy in the treatment and placebo groups, respectively (p=0.37). The risk ratio (RR) of clinical pregnancy in women receiving vitamin D3 was 0.91 (95% confidence interval-CI: 0.75 – 1.11). Compared to placebo, vitamin D3 supplementation did not significantly improve the secondary outcomes. Exploratory subgroup analyses for BMI, age, indication to IVF, ovarian reserve, interval between drug administration and initiation of the cycle and basal levels of 25-hydroxyvitamin D failed to highlight any clinical situation that could benefit from the supplementation.Conclusions: In normal weight women with preserved ovarian reserve and low vitamin D levels undergoing IVF cycles, a single oral dose of 600,000 IU of vitamin D3 does not improve the chances of clinical pregnancy. Although the findings do not support the use of vitamin D3 supplementation to ameliorate IVF success, further studies are required to rule out milder but potentially still interesting benefits as well as exploring the effectiveness of alternative modalities of supplementation.
Clinical trial of 50,000 IU vitamin D weekly to improve IVF success - Phase 4 trial announced July 2017
Vitamin D Supplementation in Vitamin Deficient Women Undergoing IVF Cycles: Does it Affect the Fertility Outcome?
Unfortunately trial is only giving vitamin D to the women, and for only 2 months
They will be measuring results over the next 12 months
Doubt that this clinical trial will be successful
50,000 IU bi-weekly to both man and woman during an entire year would have had far better success.
59% reduction in sperm count around the world in just 40 years - Mercola Aug 2017. May 2022
Skyrocketing Male Infertility May Threaten Mankind’s Survival - Mercola
- "According to the largest meta-analysis of its kind, sperm counts around the world declined by more than 50 percent, to 47 million sperm per mL, between 1973 and 2013, and continue to dwindle"
- "The most significant declines were found in samples from men in North America, Europe, Australia and New Zealand, where many had sperm concentrations below 40 million/mL — a level at which a man will have trouble fertilizing an egg"
Vitamin D was barely mentioned- Full study is on VitaminDWiki Global sperm count dropped by 59 percent in 40 years – meta-analysis Aug 2017
-  Mercola Update May 2022
- ‘Countdown to zero’: Endocrine disruptors and worldwide sperm counts MDEdge Aug 2021]
- "At the current rate of decline, the average sperm count will be zero in 2045"
- speculates on plastics, etc as endorine disrupters (no mention of Vitamin D crashing)
Eating more fish (probably Omega-3 and Vitamin D) resulted in a 16% increase in babies - May 2018
Survey of 501 couples, New York Times
Reportingo n study in Journal of Clinical Endocrinology and Metabolism https://doi.org/10.1210/jc.2018-00385- "By 12 months, 92 percent of couples who ate fish twice a week or more were pregnant, compared with 79 percent among those who ate less."
Men Are Freaking Out About Their Sperm NYT July 2018
- includes highlights of 185 studies Temporal trends in sperm count: a systematic review and meta-regression analysis 2017
52.4% between 1973 and 2011, https://doi.org/10.1093/humupd/dmx022 avaiable at DeepDyve
The word Vitamin does not occur once in the New York Times article nor the study
Vitamin D: Study Finds Impaired Fertility - May 2016
URL
RCT of Vitamin D and Fertility - daily for a year - to 16 weeks after birth
This data disagrees with a majority of studies on this pageBecame pregnant Complications Placebo 38% 52% 1400 IU 33% 23% for 1400 and 2800 IU 2800 IU 39% Statistical certainty of the percentages was not given in the abstract
- "Complications during labor, including preeclampsia and postpartum bleeding, were significantly more frequent in the placebo group compared with the combined treatment groups (52% versus 23%, P=0.005)."
- "The study found no difference in other complications including pre-term birth, miscarriage, gestational diabetes, and infections"
- No comment on any differences in Still Births, Death during first year, etc.
- Wonder if mothers getting lots of vitamin D had more alive and healthy children at the one year mark compared to placebo
Why Are Young People Having So Little Sex? Nov 2018
The Atlantic Vitamin D is not mentioned
- "...Americans are in the midst of a sex recession"
- "...crushing economic pressures, of surging anxiety rates, of psychological frailty, of widespread antidepressant use, of streaming television, of environmental estrogens leaked by plastics, of dropping testosterone levels, of digital porn, of the vibrator’s golden age, of dating apps, of option paralysis, of helicopter parents, of careerism, of smartphones, of the news cycle, of information overload generally, of sleep deprivation, of obesity. Name a modern blight, and someone, somewhere, is ready to blame it for messing with the modern libido?
The Disappearing Y Chromosome Atlantic Mag Dec 2019
It’s surprisingly common for men to start losing entire chromosomes from blood cells as they age
- "Now a new study—the largest yet of this phenomenon—estimates that 20 percent of 205,011 men in a large genetic database called the UK Biobank have lost Y chromosomes from some detectable proportion of their blood. By age 70, 43.6 percent of men had the same issue."1
No mention of Vitamin D
5X longer to induce pregnancy if male is >45
The male biological clock – How to tell the time MDEdge Oct 2021
Vitamin D in human reproduction: some answers and many more questions - Jan 2021
 Download the PDF from VitaminDWiki
Less fertile mice if low Vitamin D (fully-activated Vitamin D) - Feb 2021
- 1,25-Dihydroxyvitamin D deficiency accelerates male reproductive senescence in aging mice
- doi: 10.1152/ajpendo.00531.2020, free abstract, study is behind $25 paywall
Email from a woman who read this page, tested and then took vitamin D - Dec 15. 2022
Hello
I want to thank you for providing the information on your website. I was able to give birth to a healthy baby after 4 miscarriages.
I read many of the articles and saw the testimony a man had wrote about his wife having a baby. I had been tested for many things but my vitamin D level wasn't checked.
I ordered a test on my own and I was at a 13. I got it up to a 94 and was pregnant the next month. Taking high dose vitamin D is the only change I made and I hope I can share this knowledge with others struggling with fertility problems.
CandiceFertility and sperm73491 visitors, last modified 18 Nov, 2024, This page is in the following categories (# of items in each category)Attached files
ID Name Uploaded Size Downloads 21405 D decrease infertility - meta-analysis_CompressPdf.pdf admin 06 Jul, 2024 758.33 Kb 54 20560 Calcium_and_Vitamin_D_Homeostasis_in_Male_Fertilit_CompressPdf.pdf admin 30 Dec, 2023 230.45 Kb 148 17594 endocrine-disrupting-chemicals- Mercola May 2022.pdf admin 14 May, 2022 194.96 Kb 433 14941 Human fertility some answers, more questions.pdf admin 28 Jan, 2021 68.97 Kb 1457 10244 Fertile meta 3.jpg admin 25 Jul, 2018 35.77 Kb 5013 10243 Fertile meta.jpg admin 25 Jul, 2018 19.10 Kb 5873