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High dose vitamin D3 made a big difference in my trauma patients' quality of life, especially those with severe traumatic brain injuries. A concussion is a mild traumatic brain injury. See "Figure 1 and arrow" on the PDF image below.
This is a 29 year old female who was assaulted by her boyfriend. He stabbed her in the abdomen first ( see Figure 2), and then in the top of the head (see Figure1). The force broke the handle of the knife blade and left 6 inches of the knife blade in the patients brain.
She arrived in the emergency room with altered mental status, paralysis of her right arm from the knife in her skull, a very low blood pressure (shock), and blood in her abdomen. This patient had two life threatening injuries that needed to be operated on immediately by my trauma team and the neurosurgeons simultaneously!
In surgery, patient had a right collapsed lung, a severely damaged gall bladder which we removed, a large laceration (hole) in the liver from the knife stab to the abdomen which was repaired, while the neurosurgeons above us removed the knife and damaged brain tissue.
Patient was started on our high dose vitamin D3 protocol immediately after surgery. Patient was discharged 6 days later. She was continued on vitamin D3 after discharge. Her right arm paralysis and altered mental status was completely resolved at 6 weeks. We have used high dose vitamin D3 successfully in gunshot wounds to the head, concussions, strokes, severe traumatic brain injuries, heart attacks, congestive heart failure, pneumonia, colds, flu, wound infections, and chronic pain.
Remember that vitamin D3 is a "true hormone" that becomes even more important any time the human body is under emotional or physical stress from any illness or injury. I call vitamin D3 "God's miracle vitamin" and the most important hormone during any stressful human events. Now, I hope that using vitamin D3 to treat concussions makes more sense. As you can see, I have been very successful treating gunshot and knife stab wounds to the head, severe traumatic brain injuries, and most neurological disorders using high dose vitamin D3.
The above is a narative description of Case Report: Traumatic Injuries Requiring Simultaneous Emergent Operative Procedures, Knife Wounds to the Top of the Skull and the Abdomen – Nov 2017
Download the PDF from VitaminDWiki
Note: The word VITAMIN does not occur once in the PDF
See also VitaminDWiki
A few entries concerning Dr. Matthews
- Vitamin D could knock out COVID-19 in 3 months – Dr. Matthews interview Oct 2020
- Critically Ill or injured patients need 30-50 ng of Vitamin D – Matthews March 2020 in PubMed
- Vitamin D, glutathione, and heat shock protein to treat concussions, etc. – US Patent Dec 2019
- Vitamin D, trauma, and blacks - Dr. Matthews interview with transcript - Jan 2019
- Low Vitamin D symptoms, need 50-80 ng, he takes 5,000 IU – Matthews interview Dec 2019
- Traumatic Brain Injuries routinely treated by Vitamin D, Omega-3, Progesterone and Gluatmine May 2019
- Vitamin D and Glutamine reduced Trauma Center deaths by half – Matthews March 2017
- ICU cost reduced by at least 27,000 dollars if get high dose vitamin D in first week - April 2017
- Result of 5 years of Vitamin D given to athletes in a high school: $60 million in scholarships, almost zero concussions, etc. - June 2016
- 50,000 IU Vitamin D daily for 5 days (7 days if use NASOGASTRIC tube)
Loading Dose of Vitamin D category has the following
see also Overview Loading of vitamin D Overview Toxicity of vitamin D
Better than Daily 1: Fewer chances to forget, 2) Gets past receptor barrier
Injection category has
It appears that over 1 million Vitamin D loading doses have been taken
Doses ranged from 100,000 to 600,000 IU over a period of a day to a month
No reports of serious adverse reactions
Many studies report on the benefits resulting from loading doses
TOP articles in Loading Dose of Vitamin D
- Vitamin D loading dose of 30,000 IU twice a week is safe and effective – RCT July 2023
- Large dose Vitamin D before surgery was found to help by 35 studies
- Vitamin D is needed before most surgeries – many studies and RCTs
- 400,000 IU of vitamin D 3 days after COVID symptoms reduced 14 day mortality by 3X – Annweiler RCT May 2022
- High-dose Vitamin D safe for children (10,000 IU daily, 600,000 IU bolus) – meta-analysis April 2022
- Take lots of Vitamin D at first signs of COVID
- Rapid Vitamin D Delivery May Result in Better COVID Outcomes - Dec 9, 2021
- Vitamin D loading doses quickly and safely raise levels – meta-analysis Dec 2021
- Childhood cancers – give Vitamin D loading dose if low – Oct 2021
- French recommended 200,000 IU of Vitamin D to stop COVID-19 - Jan 2021
- Vitamin D loading dose was as effective as daily dosing (rickets in this case) – RCT July 2021
- Stoss (loading) dose of vitamin D resulted in bigger response at 30 days (again) – RCT April 2021
- Vitamin D loading dose (stoss therapy) proven to improve health
- Low trauma bone fractures in seniors – considering Vitamin D loading dose for all, without testing – Nov 2019
- Intensive Care (ICU) helped by Vitamin D – review of past and on-going studies – Dec 2018
- Vitamin D restoration then monthly was the most popular dosing by trials – Nov 2018
- Rickets virtually cured by 90,000 IU of Vitamin D along with daily Calcium – RCT Nov 2018
- Rapidly restore Vitamin D levels with 10,000 IU per kg for children in ICU – RCT 2024
- Reasons for Low Vitamin D and what to do
- Healthy in Seven Days - Loading dose of Vitamin D – book 2014
- Can get 50,000 IU Vitamin D anywhere on the globe
Items in both categories Trauma and Loading Dose are listed here:
- Surgery complications cut in half by 300,000 IU of vitamin D 2 weeks before (hip and knee) – RCT May 2024
- Some ICU patients got 540,000 IU of Vitamin D: good responders lived longer than controls or poor responders – RCT June 2024
- Large dose Vitamin D before surgery was found to help by 35 studies
- Vitamin D is needed before most surgeries – many studies and RCTs
- Half as much AFIB after bypass if 600,000 IU of vitamin D before surgery – RCT April 2022
- ICU mortality reduced by non-oral vitamin D – meta-analysis May 2021
- Taking Vitamin D just before and after surgery helps (open-heart in this case) – RCT Feb 2021
- Half as many problems if take Vitamin D (300,000 IU) before thyroidectomy – RCT Jan 2021
- Fewer days in hospital if 300,000 IU of vitamin D before brain surgery - RCT Feb 2021
- ICU Vitamin D injection (300,000 IU) helped - RCT Feb 2021
- Those getting an injection of 300,000 IU Vitamin D got out of the ICU a week sooner – RCT Dec 2020
- ICU patients greatly helped by Vitamin D loading doses – if gut-friendly – Oct 2020
- Fewer days in ICU after 300,000 IU of vitamin D, but not 540,000 – meta-analysis Aug 2020
- 3X less Septic Shock in children with sepsis getting 150,000 IU of Vitamin D - RCT June 2020
- 100,000 IU daily of Vitamin D for 5 days increased Hemoglobin in Mechanically Ventilated adults – RCT Jan 2018
- Traumatic Brain Injury – 120,000 IU of Vitamin D resulted in 3 fewer days on ventilators – RCT March 2020
- Hip surgery with multiple doses of 50,000 IU of vitamin D weekly both before and after – RCT 2023
- Use of Vitamin D in a trauma surgery - Dr. Matthews on Facebook – Jan 2020
- Surgeries often deplete Vitamin D - 300,000 IU resulted in little response – Nov 2018
- 10 fewer days of ICU Mechanical Ventilation 300,000 IU injection of vitamin D – RCT March 2019
- Intensive Care (ICU) helped by Vitamin D – review of past and on-going studies – Dec 2018
- ICU adults getting 540,000 IU of Vitamin D were 2X more likely to be alive 30 days later – RCT June 2019
- Traumatic Brain Injury recovery helped by injection of 100,000 IU of Vitamin D – March 2019
- Rapidly restore Vitamin D levels with 10,000 IU per kg for children in ICU – RCT 2024
- Esophageal Cancer surgery helped by 300,000 IU of Vitamin D – RCT Sept 2018
- Severe sepsis may be prevented by 400,000 IU of vitamin D – RCT 2023
- Critically ill children – randomized clinical trial to give single doses of up to 400,000 IU of vitamin D – 2019
- Vitamin D loading doses reduce ICU mortality by 30 percent – meta-analysis April 2017
- Hospital ICU added high dose vitamin D - malpractice lawsuit costs dropped from 26 million dollars to ZERO - Oct 2016
- Children in Intensive Care need Vitamin D loading dose of 10000 IU per kg (nearing a consensus) - Oct 2016
- Vitamin D Loading dose - 20,000 IU daily is not enough if obese, etc. (Cancer) great table and chart – Oct 2016
- Rapid Normalization of Vitamin D in Critically Ill Children (10,000 IU per kg) – clinical trial
- VITdAL-ICU - AMA RCT Sept 2014
- Critically ill need vitamin D – how much and which test to use is TBD – Nov 2014
- ICU survival increased with vitamin D single 540K IU loading dose - JAMA Sept 2014
- 540000 IU before ICU raised vitamin D by 25 ng in 2 days – March 2011
- Hip surgery followed by 100000 IU then 1000 IU of vitamin D daily – June 2010
- 600,000 IU intramuscular D3 helped BMD after pancreatic surgery – June 2010
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