Microplastics change the gut microbiome - Jan 2025

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Association between microplastics and the functionalities of human gut microbiome

Ecotoxicology and Environmental Safety Volume 290, 15 Jan 2025 https://doi.org/10.1016/j.ecoenv.2024.117497
China

Highlights

• Microplastics were correlated with microbial invasion-related virulence factors.
• Microplastics were associated with microbial quorum sensing and transporter systems.
• Microplastics were correlated with microplastic biodegradation genes.

As an integral part of humans, the gut microbiome plays a significant role in the physiological and pathological processes of the host, and dysbiosis of the gut microbiome is linked to various diseases. The impact of microplastics on the diversity and composition of human gut microbiome has been reported previously. However, effects of microplastics on the functionality of the gut microbiome in humans have not been well studied. In the present study, concentrations of microplastics in human blood were detected through pyrolysis-gas chromatography/mass spectrometry in 39 adults. Five types of microplastics were found in human blood, including polyvinyl chloride, polyethylene, polypropylene, polystyrene, and polyamide 66. Shotgun metagenomic sequencing was further employed to analyze the metagenomes of the human stool samples and fecal samples from mice exposed to microplastics. Associations were found between microplastics and microbial species, as well as microbial genes encoding invasion-related virulence factors, quorum sensing, autoinducer and transporter system, and microplastic biodegradation enzymes. The findings are of significance to improve the understanding of functional changes in the gut microbiome associated with microplastic exposure, as well as raising awareness regarding the health risks of microplastics in the human population.
 Download the PDF from VitaminDWiki

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VitaminDwiki – Microbiome contains

Some of the 40 Microbiome articles

• Nutrients, Microbiome, and Chronic Diseases - April 2023
• Fecal transplants - many studies
• Healthy microbiota might reduce COVID-19 – several studies
• Poor absorption of Vitamin D is strongly related to type of gut bacteria – Dec 2020
• Vitamin D and the Host-Gut Microbiome: A Brief Overview– June 2020
• Parkinson's Disease and gut microbiome - several studies
• Vitamin D levels change Gut Microbiota – 25 study review Sept 2021
• Gut Microbiota: improved by Vitamin D – narrative review – July 2021
• Gut microbiome massively changed by weekly vitamin D – July 2015
• Also: Google Scholar on Microbiome includes:The cancer microbiome - June 2019, The Healthy Microbiome—What Is the Definition of a Healthy Gut Microbiome? - Jan 2021, The gut microbiome in neurological disorders - Feb 2020, Understanding the role of the gut microbiome in gastrointestinal cancer: A review -Jan 2023, The human microbiome and COVID-19: A systematic review - June 2021, *Interaction between drugs and the gut microbiome - July 2020

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VitaminDwiki – Microplastics now causing problems in most life forms - many studies

Table of Contents as of Dec 2024

• What changes can I make to avoid microplastics (from water, air, food, etc) - Perplexity AI July 2024
• Perplexity AI summary of this page as of Sept 22, 2024
• Microplastics and Human Health: Unveiling the Gut Microbiome Disruption and Chronic Disease Risks - Dec 2024?
• Fate of Microplastics in Wastewater Treatment Plants - book Nov 2024
• Polystyrene microplastics found in Prostate cancers, but not elsewhere in Prostate (small study) - Oct 2024
• Microplastics in the Olfactory Bulb of the brain in 8 out of 15 people - Sept 2024
• Microplastics in ecological system: Their prevalence, health effects, and remediation - Sept 2024
• What Microplastics Are Doing to the Brain, Body, and Reproductive Systems - Dr. Patrick Sept 2024
• A sea fugus has learned how to slowly eat polyethylene that has been exposed to UV (at the surface) - July 2024
• Microplastics found in 8 human organ systems - scoping review Aug 2024
• Increased vascular blockage associated with increased microplastics – Aug 2024
• Microplastics especially found in pancreatic, lung, gastric and colorectal tumors – Sept 2024
• Breastmilk proteins altered by microplastics - July 2024
• Surprise: Biodegradable microplastics may actually be worse for soil and plants - July 2024
• Microplastics in many people with calcified blood vessels (24% of adults have vascular calcification) - Dec 2023
• Microplastics found in ALL 16 patients with bone marrow diseases (leukaemia, etc.) - July 2024
• Microplastics in milk for infants (both breast and formula) change proteins that may affect health - July 2024
• Women with Cervical Cancers have high levels of microplastics in both cervix and blood - June 2024
• How microplastics and nanoplastics affect systems of the human body - review June 2024
• Human Toxicity of Nano- and Microplastics - book chapter behind paywall - June 2024
• Microplastics and Fertility
• Plastic takeaway food containers may cause human intestinal damage (200,000 particles per cm2 when heated) – June 2024
• Good news: clear, black, shiny plastics degrade into microplastics far more slowly (not adsorb UV) - May 2024
• Microplastics and Their Implications for Human Health: A Scientific Exploration – May 2024
• Micro and nanoplastics in plaque: 4.5 X higher risk of cardiovascular events and death - May 2024
• Fish ingesting microplastics have gut, reproduction, brain injury etc, problems – May 2024
• Probiotics should fight microplastics problems in the gut: A Comprehensive Review - May 2024
• Impact of microplastics on human health and aquatic species - May 2024
• 150 plastic plants and chemical industries = Cancer Alley: cancer rates 50 X higher - May 2024
• Chart of studies of microplastics in humans - 2020
• Review of many microplastic medical studies - substack March 2024
• Health risk of human exposure to microplastics: a review - March 2024
• Microplastics appear to impact human organs ($65 paywall) - March 2024
• Microplastics Linked to Heart Attack, Stroke and Death - Scientific American March 2024
• Plaques were removed: those having microplastics had a 4.5 X increased risk of stroke, heart attack, etc. - March 2024
• Study was described in a 8 minute video March 2024 - 2 charts from PDF
• Effects of Microplastics and Nanoplastics in Agro-ecosystems and Human Health: A review - Jan 2024
• Detection of Various Microplastics in Patients Undergoing Cardiac Surgery - July 2023
• Microplastics reduced bio-avalability of Zinc and Magnesium essential for vitamin D metabolism (in mice) - July 2023
• Microplastics and human health: Integrating pharmacokinetics - April 2023
• Microplastics as an Emerging Threat to the Global Environment and Human Health - July 2023
• Microplastics and human health: Integrating pharmacokinetics - April 2023
• The Plastic Within: Microplastics Invading Human Organs and Bodily Fluids Systems - Nov 2023
• Microplastics contamination in food products: Occurrence, analytical techniques and potential impacts on human health - Feb 2024
• The potential impacts of micro-and-nano plastics on various organ systems in humans - Lancet Jan 2024
• VitaminDWiki - Autism risk if toxins, heavy metals, microplastics, etc during pregnancy (unless add Vitamin D) – Feb 2024
• Microplastics might be a cause of Parkinson's - Nov 2023
• Microplastics causing problems in Zebra fish - reduced by 40% if Vitamin D was added - Nov 2023
• People are now INHALING a credit card's worth of plastics each week - Sept 2023
• Study: people could be EATING a credit card's worth of microplastics per week- 2019
• Microplastics may increase snow melt, and thus increase climate warming
• 8 Types of Plastic Discovered in People Who Had Heart Surgery - Sept 2023
• Microplastics in fruit and vegetables
• 100K-400K NANOplastic particles in a liter of bottled water - Jan 2024
• Microplastics perturb macrophages in the lab - May 2023
• 94% of US water contains microplastics
• 500 tons of RF chaff into the US annually, vs 878 tons of microplastics into the ocean from all washing machines US and Canada - Feb 2024
• Web- seabirds, humans, baby formula, breast cancer
• Rainfall in the Rocky Mountains contains microplastics - 2019
• Microplastics in Mosquitoes - Sept 2018
• Zero Water countertop filter eliminates microplastic (nanoplastic too?)
• Chart of the size of nano and microplastics removed by type of water filter - Jan 2024?
• Visualizing the amount of microplastic we eat - Dec 2019
• 5+ VitaminDWiki pages with BPA in title
• Your clothes can shed 700,000 microplastic fibers in a single wash - Feb 2023
• A Detailed Review Study on Potential Effects of Microplastics and Additives of Concern on Human Health - Feb 2020
• Microplastics Pollution as an Invisible Potential Threat to Food Safety and Security, Policy Challenges and the Way Forward - Dec 2020
• VitaminDWiki – VitaminDWiki – PFAS (forever chemicals) reduce Vitamin D and VDR, cause health problems - many studies
• VitaminDWiki – Interactions with Vitamin D contains