Association of Vitamin D3 Level with Breast Cancer Risk and Prognosis in African-American and Hispanic Women
Cancers 2017, 9(10), 144; doi:10.3390/cancers9100144
Yanyuan Wu 1,2, Marianna Sarkissyan 1, Sheilah Clayton 1, Rowan Chlebowski 2,3 and Jaydutt V. Vadgama 1,2,*
Items in both categories Breast Cancer and Dark Skin are listed here:
- Cancer of breast is highest in dark-skinned women (low Vitamin D: dark skin and obese) - Feb 2022
- Breast cancer in blacks – 5X increased risk of triple negative if low vitamin D – Oct 2017
- Hypothesis: Vitamin D is related to breast cancer racial disparities in the US - Sept 2012
- Genes may account for some of AA Breast Cancer – April 2012
- Breast cancer worse for black women – Sept 2011
- Breast cancer more deadly for blacks than whites
Overview Breast Cancer and Vitamin D contains the following:
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25 Meta-analyses of Vitamin D and Breast Cancer
example: 2X reduction of deaths from Breast Cancer if have enough Vitamin D.- Appears that having lots of Vitamin D will reduce by 3 X the chance of Breast Cancer
wonder just how much more proof is needed- Breast Cancer 4X more likely if have poor genes
- Cancer - Breast category listing has
259 items along with related searches - Breast Cancer treatment – Vitamin D was the most-popular supplement – Jan 2023
- Breast Cancer again associated with low vitamin D – 15th meta-analysis Sept 2020
- Vitamin D reduced Breast Cancer mortality in 9 out of 9 studies, yet still no consensus – April 2019
- Vitamin D both prevents and treats Breast Cancer – 2019
- Genes may account for some of AA Breast Cancer – April 2012
- More US deaths due to cancer than heart if dark skinned – Sept 2012
- Triple-negative breast cancer is 3X more frequent if less than 32 ng of vitamin D – March 2012
- Blacks may not need as much Vitamin D (for their bones)
Download the PDF from VitaminDWikiBackground: This study investigated the association of vitamin D3 levels with breast cancer risk and progression in African-Americans and Hispanics. Methods: A total of 237 African-American (Cases = 119, Control = 118) and 423 Hispanic women (Cases = 124, Control = 299) were recruited in the study. Blood samples were collected at the time of breast cancer screening and prior to cancer treatment for 4 weeks on average for the cases. The serum 25-hydroxyvitamin D (25(OH)D3) was measured at a Quest-Diagnostics facility.
Results: The results showed that 69.2% of African-Americans and 37.8% of Hispanics had 25(OH)D3 levels below 20 ng/mL. The 25(OH)D3 level below 20 ng/mL was significantly associated with breast cancer in both African-Americans (OR = 2.5, 95% CI = 1.3–4.8) and Hispanics (OR = 1.9, 95% CI = 1.1–3.0). However, the predicted probabilities of breast cancer in African-Americans were significantly higher than in Hispanics (p < 0.001).
The 25(OH)D3 below 20 ng/mL was significantly associated with triple negative breast cancer (TNBC) in African-Americans (OR = 5.4, p = 0.02, 95% CI = 1.4–15), but not in Hispanics in our cohort of participants. Levels of 25(OH)D3 below 26 ng/mL predicts a decrease in disease-free survival, but it was not an independent predictor.
Conclusions: Our data shows an association between 25(OH)D3 levels and the risk of breast cancer. Further studies on the relationship between 25(OH)D3 level and breast cancer risk are warranted.
Breast cancer in blacks – 5X increased risk of triple negative if low vitamin D – Oct 2017Printer Friendly Follow this page for updates5128 visitors, last modified 11 Jun, 2022, This page is in the following categories (# of items in each category) - Appears that having lots of Vitamin D will reduce by 3 X the chance of Breast Cancer