| Root Cause | Examples |
| 🔪 Environmental toxins | Asbestos, heavy metals, pesticides, glyphosate, EMFs, nanomaterials |
| 🥛 Dietary toxins | Ultra-processed foods (UPFs), high-carb diets, seed oils, refined sugars |
| 🧬 Genetic susceptibility | Inherited detox enzyme polymorphisms, mitochondrial DNA instability |
| 🦠 Chronic infections | HPV, EBV, H. pylori, CMV, mycoplasma |
| 🪡 Micronutrient deficiencies | Low zinc, selenium, magnesium, folate, B12, vitamin C, vitamin D Ames, 2004 |
| 🧠 Developmental insults & stress | Prenatal toxin exposure, trauma, neuroendocrine-immune dysregulation |
| 💉 Medical iatrogenesis | Chemotherapy, radiation, immunosuppressants, unnecessary antibiotics |
clipped from Rethinking Cancer from the Roots: A Root Cause Analysis Orthomolecular Medicine News Service July 2025
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